Gündüz R.Yıldız B.S.Çetin N.Özgür S.Çizgici A.Y.Tülüce K.Tülüce S.Y.Özen M.B.Duman S.Bayturan Ö.2024-07-222024-07-22202221492263http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/12646Background: Coronary artery perforations are one of the most feared, rare, and catastrophic complication of percutaneous coronary intervention. Despite the remarkable increase in coronary angiography and percutaneous coronary intervention, there is no large database that collects coronary artery perforation for the Turkish population. Our study aimed to report our experience over a 10-year period for clinical and angiographic characteristics, management strategies, and outcomes of coronary artery perforation during the percutaneous coronary intervention at different cardiology departments in Turkey. Methods: The study data came from a retrospective analysis of 48 360 percutaneous coronary intervention procedures between January 2010 and June 2020. A total of 110 cases who had coronary artery perforation during the percutaneous coronary intervention were found by angiographic review. Analysis has been performed for the basic clinical, angiographic, procedural characteristics, the management of coronary artery perforation, and outcome of all patients. Results: The coronary artery perforation rate was 0.22%. Out of 110 patients with coronary artery perforation, 66 patients showed indications for percutaneous coronary intervention with acute coronary syndrome and 44 patients with stable angina pectoris. The most common lesion type and perforated artery were type C (34.5%) and left anterior descending (41.8%), respectively. The most observed coronary artery perforation according to Ellis classification was type III (37.2%). Almost 52.7% of patients have a covered stent implanted in the perforated artery. The all-cause mortality rate of coronary artery perforation patients in the hospital was 18.1%. Conclusion: The observed rate of coronary artery perforation in our study is consistent with the studies in this literature. However, the mortality rates related to coronary artery perforation are higher than in other studies in this literature. Especially, the in-hospital mortality rate was higher in type II and type III groups due to perforation and its complications. Nevertheless, percutaneous coronary intervention should be done in selected patients despite catastrophic complications. Copyright@Author(s) - Available online at anatoljcardiol.com.EnglishAll Open Access; Gold Open Access; Green Open AccessCoronary AngiographyCoronary Artery DiseaseCoronary VesselsHeart InjuriesHumansPercutaneous Coronary InterventionRetrospective StudiesStentsTreatment OutcomeVascular System Injuriesacetylsalicylic acidangiotensin receptor antagonistbeta adrenergic receptor blocking agentbiochemical markercalcium channel blocking agentclopidogrelcreatine kinasedipeptidyl carboxypeptidase inhibitorhydroxymethylglutaryl coenzyme A reductase inhibitorivabradinenitrateprasugrelprotamine sulfatetrimetazidinetroponin Iacute coronary syndromeagedangina pectorisangiographyartery lesionArticlebody masscalcificationchronic total occlusionclassificationclinical outcomecontrolled studycoronary angiographycoronary arterycoronary artery bypass graftcoronary artery perforationdiabetes mellitusdisease severity assessmentechocardiographyelectrocardiogramelectronic medical recordEllis classificationevidence based practiceextravasationheart infarctionheart tamponadehumanhypertensionInternational Classification of Diseasesmajor clinical studymanagementmedical recordmortality ratemulticenter studynon ST segment elevation myocardial infarctionparadoxical pulsepercutaneous coronary interventionpericardial effusionphysicianrandomized controlled trialrisk factorST segment elevation myocardial infarctionsystolic blood pressureadverse device effectadverse eventblood vessel injurycoronary artery diseasecoronary blood vesseldiagnostic imagingheart injuryretrospective studystenttreatment outcomeArticle10.5152/AnatolJCardiol.2022.1337