Mitochondrial dysfunction particularly in adipocytes may be an important triggering factor for type 2 diabetes

Erol A.2024-07-222024-07-22200603069877http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19500[No abstract available]EnglishAdipocytesDiabetes Mellitus, Type 2HumansLipid MetabolismMitochondriaMitochondrial DiseasesModels, Biologicaladenosine triphosphateDNAglucose transporterperoxisome proliferator activated receptor gamma coactivator 1alphareactive oxygen metabolitesuperoxideuncoupling protein 2adipocytecell metabolismdiabetic patientdisease coursedisorders of mitochondrial functionsenergy metabolismexercisefatty acid oxidationgene expressiongene mutationgene overexpressionglucose homeostasisglucose tolerancehyperglycemiaimpaired glucose toleranceinsulin releaseletterlipid metabolismmitochondrial DNA depletionmitochondrial respirationnon insulin dependent diabetes mellitusnonhumanobesityoxidative phosphorylationoxidative stresspancreas islet beta cellpathophysiologypriority journalMitochondrial dysfunction particularly in adipocytes may be an important triggering factor for type 2 diabetesLetter10.1016/j.mehy.2006.05.007