Gencoglan G.Inanir I.Gunduz K.2024-07-222024-07-22201015298019http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18438Psychocutaneous conditions are frequently encountered in dermatology practice. Prurigo nodularis and lichen simplex chronicus are two frustrating conditions that are classified in this category. They are often refractory to classical treatment with topical corticosteroids and antihistamines. Severe, generalized exacerbations require systemic therapy. Phototherapy, erythromycine, retinoids, cyclosporine, azathiopurine, naltrexone, and psychopharmacologic agents (pimozide, selective serotonin reuptake inhibitor antidepressants) were tried with some success. Here five cases with lichen simplex chronicus and four cases with prurigo nodularis, who responded well to gabapentin, are presented. © 2010 Wiley Periodicals, Inc.EnglishAdolescentAdultAgedAminesAnalgesicsAnticonvulsantsCyclohexanecarboxylic AcidsFemalegamma-Aminobutyric AcidHumansMaleMiddle AgedNeurodermatitisPrurigoTreatment OutcomeYoung Adultantidepressant agentantihistaminic agentcorticosteroidgabapentinadultagedarticleclinical articleclinical observationcontrolled studydisease durationdrug dose increasedrug dose reductiondrug effectfemalefollow uphumanmalemedical historyneurodermatitisphototherapyprurigo nodularispruritussedationside effectskin diseasetreatment durationunspecified side effectArticle10.1111/j.1529-8019.2010.01314.x