Demet YALDIZArkın ACARŞeyda ÖRS KAYAZekiye AYDOĞDUSoner GÜRSOYSadık YALDIZ2024-07-242024-07-2420191301-5680http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/22468Background: This study aims to investigate whether papillarypredominant histological subtype can predict poor survival inlung adenocarcinoma.Methods: Between January 2005 and December 2016,a total of 80 patients with papillary predominant subtype lungadenocarcinoma (70 males, 10 females; mean age 60.7 years;range, 42 to 79 years) operated in our clinic were included in thestudy. These patients were compared with those having lepidic,acinar, and mucinous subtypes. Overall and five-year survivalrates were evaluated.Results: Five-year survival was 40.5% in papillary predominanthistological subtype, while this rate was 70.9%, 59.0%, and66.6% in lepidic, acinar, and mucinous subtypes, respectively.Papillary subtype showed significantly poor survival comparedto lepidic (p=0.002), acinar (p=0.008), and mucinous subtypes(p=0.048). In Stage 1 disease, it was more evident (papillary,47.5%, lepidic 86.9% [p=0.001], acinar 69.3% [p=0.040], andmucinous 90.0% [p=0.050]).Conclusion: Our study results suggest that papillary predominantsubtype predicts poor survival in lung adenocarcinoma and thesecases may be candidates for adjuvant treatment modalities evenin the earlier stages of disease.eng[Fen > Tıp > Kalp ve Kalp Damar Sistemi, Fen > Tıp > Cerrahi]Araştırma Makalesi10.5606/tgkdc.dergisi.2019.17284