Çetinarslan T.Fölster-Holst R.Van Gysel D.Buchner M.Happle R.2024-07-222024-07-22202407368046http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11576Incontinentia pigmenti (IP) is a rare X-linked dominant, male-lethal disorder characterized by pathognomic skin lesions. As described in the literature the typical cutaneous changes follow the pattern of Blaschko's lines and develop in four stages that usually start at birth. Stage 1 is called vesicular, bullous or inflammatory. The vesicles are rapidly filled with eosinophils and thus turn into pustules. Thus, the term “pustular” is relevant to the first phase of IP, and the stage can be considered as “vesiculopustular/inflammatory” to be more precise than “vesicular” or “bullous.”. © 2023 Wiley Periodicals LLC.EnglishBlisterEosinophilsHumansIncontinentia PigmentiInfant, NewbornMaleRare DiseasesSkinacneacrodermatitis continuaArticlebullous skin diseasecandidiasiscentral nervous systemcongenital syphilisdisease exacerbationeosinophilepidermolysis bullosaeyegenegene mutationgenodermatosisherpes simplexhistopathologyhumanIKBKG geneimpetigoincontinentia pigmentiinflammationLangerhans cell histiocytosisnailnewbornpustulescabiesskinskin defectstagingStaphylococcus infectiontoothvesiculopustuleX chromosome linked disorderblisterincontinentia pigmentimalepathologyrare diseaseArticle10.1111/pde.15465