The Knoevenagel-Doebner Reaction on 1,2-O-(2,2,2-Trichloroethylidene) Derivatives of D-Gluco- and D-Manno-furanose

Kök, GKarayildirim, TAy, KAy, E2025-04-102025-04-10http://hdl.handle.net/20.500.14701/40471The synthesis of new alpha,beta-unsaturated furanuronic acid derivatives of alpha-gluco-(3), beta-gluco-(6) and beta-manno-chloraloses (9) via a convenient one pot procedure using the Knoevenagel-Doebner reaction approach are described. The dialdofuranose derivatives were reacted with malonic acid under Knoevenagel-Doebner reaction conditions and (E)-alpha,beta-unsaturated furanuronic acid derivatives were obtained.EnglishThe Knoevenagel-Doebner Reaction on 1,2-O-(2,2,2-Trichloroethylidene) Derivatives of D-Gluco- and D-Manno-furanoseArticle1420-3049