Ozer, EA2024-07-182024-07-182249-48471658-6093http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/4404Despite the technological advances in the mechanical ventilation in neonatal intensive care units (NICUs), the lungs of preterm infants are still susceptible particularly to ventilator-induced lung injury. The purposes of lung-protective strategy in preterm infants are to prevent atelectrauma, limit tidal volume to avoid overdistension, and minimize oxygen toxicity. Available data suggest that these goals can be successfully achieved by different modes of respiratory support including ideal ventilation. It is important that ventilation with large tidal volumes should be avoided. Lung-protective ventilation in the newborn infants has been a recent trend as a primary mode of ventilation support for early management of respiratory distress syndrome. To reduce the risk of ventilator-induced oxygen toxicity, supplemental oxygen should be guided by pulse oximetry. In this study, current lung-protective ventilation methods in NICU are reviewed.EnglishINTERMITTENT POSITIVE-PRESSURERESPIRATORY-DISTRESS-SYNDROMEFREQUENCY OSCILLATORY VENTILATIONTARGETED-VOLUME VENTILATIONAIRWAY PRESSUREPRETERM INFANTSMANDATORY VENTILATIONMECHANICAL VENTILATIONSURFACTANT REPLACEMENTGAS-EXCHANGEReview