Alkan F.Dogan G.Kaslrga E.Coskun S.2024-07-222024-07-22202110479511http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13449We aimed to investigate the effect of Celiac disease on myocardial functions and aortic elasticity parameters. Materials and Methods: Thirty children with Celiac disease and 30 healthy children were enrolled in the study. Both the groups were similar in terms of age and gender. Cardiac functions of all children in the patients and control group were evaluated using conventional transthoracic echocardiography and tissue Doppler imaging. Aortic strain, distensibility, and stiffness index were calculated by M-mode echocardiography. Results: The demographic findings, height, weight, and body mass index of cases were similar among two groups. No statistical difference was found between E wave velocity for conventional transthoracic echocardiography and tissue Doppler imaging measurements of the mitral valve; early diastolic flow peak velocity, A wave velocity; late diastolic flow peak velocity; and E/A ratio. Isovolumetric relaxation time and isovolumetric contraction time ratios were statistically different between the groups (p = 0.000, p = 0.000, p = 0.000). The myocardial performance index calculated according to the pulse Doppler measurement results was found to be statistically different between the groups (p = 0.000). There was no statistical difference between the groups in terms of aortic strain, distensibility, and stiffness index. Conclusion: In this study, both conventional transthoracic echocardiography and tissue Doppler imaging revealed the affection of the myocardial functions during systole and diastole in children with Celiac disease. Therefore, early follow-up and routine cardiac evaluation of celiac patients may be appropriate due to the increased risk of cardiac affection. © 2021 Cambridge University Press. All rights reserved.EnglishA wave velocityadolescentadultage distributionaortaaortic distensibilityaortic strainarterial stiffnessArticlebody heightbody massbody weightcardiovascular parametersceliac diseasechildclinical articlecontrolled studydemographyE wave velocityearly diastolic flow peak velocityelasticityfemaleheart contractionheart functionheart muscle relaxationhumanlate diastolic flow peak velocityM mode echocardiographymalemitral valverelaxation timesex differencetissue Doppler imagingtransthoracic echocardiographyArticle10.1017/S1047951120004461