Engin C.D.Ekinci U.B.Selver A.Saatçi A.O.2024-07-222024-07-22202021498709http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/14264The aim of this study was to report the outcome of topical brinzolamide 1% treatment on macular cystoid lesions resembling retinoschisis in 4 patients diagnosed with posterior microphthalmia. The medical records of 4 patients with a clinical diagnosis of posterior microphthalmia who had started topical brinzolamide 1% treatment were reviewed. Visual acuity, central foveal thickness, and cystoid lesion area percentage were used to evaluate treatment response. In the follow-up, there was a decrease in central foveal thicknesses and cystoid lesion area percentages in both eyes of 3 of the patients. However, 1 patient showed increases in both parameters. Visual acuity remained stable in 5 eyes and increased in 3 eyes. Topical brinzolamide treatment may have some positive effects on macular cystoid lesions in selected cases. © 2020 by Turkish Ophthalmological Association Turkish Journal of Ophthalmology, published by Galenos Publishing House.EnglishAll Open Access; Gold Open Access; Green Open AccessAdministration, TopicalAdolescentAdultCarbonic Anhydrase InhibitorsChildChild, PreschoolFemaleHumansMacular EdemaMaleMicrophthalmosSulfonamidesThiazinesTomography, Optical CoherenceVisual Acuitybrinzolamidebrinzolamidecarbonate dehydratase inhibitorsulfonamidethiazine derivativeadolescentadultanterior eye chamber depthArticleB scancase reportcentral foveal thicknesscentral retinal thicknesschildclinical articledrug efficacyeye axis lengthfemalefluorescence angiographyfollow upfundus flourescein angiographyhumanintraocular pressuremalemicrophthalmiaretina examinationretina macula cystoid edemaretrospective studyspectral domain optical coherence tomographytreatment responsevisual acuitycomplicationmacular edemamicrophthalmiaoptical coherence tomographypreschool childprocedurestopical drug administrationvisual acuityArticle10.4274/tjo.galenos.2019.40504