Batum M.Kısabay Ak A.Çetin G.Çelebi H.B.G.Çam S.Mavioğlu H.2024-07-222024-07-22202200207454http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13082Introduction: Episodic ataxia is a clinical condition characterized by episodes of balance and coordination problems that last minutes to hours. It can be inherited or sporadic, and it can be seen sporadically in epilepsy, basilar migraine, multiple sclerosis, vertebrobasilar ischaemia, and labyrinth diseases. Methods: In this article, we present a case of a patient who had a coincidental occurrence of episodic ataxia type 2 (EA2) and multiple sclerosis (MS) Results: The patient who had a previously unidentified heterozygous mutation in the calcium voltage-gated channel subunit alpha 1 A gene (CACNA1A). Conclusion: There is no publication in the literature reporting the co-occurrence of MS and EA2. This combination may be coincidental in this patient, or it may be a relationship that has not yet been scientifically revealed. © 2020 Informa UK Limited, trading as Taylor & Francis Group.EnglishAtaxiaCalcium ChannelsHumansMigraine with AuraMultiple Sclerosisacetazolamidecalcium voltage gated channel subunit alpha 1acarbamazepineglatiramerimmunoglobulin Gmethylprednisoloneoligoclonal bandunclassified drugvalproic acidvoltage gated calcium channelcalcium channelabdominal painArticleataxiaataxic gaitblurred visioncase reportcaudate nucleuscerebrospinal fluid analysiscervical spinal cordclinical articlecorticosteroid therapydiplopiadizzinessdrug dose reductiondrug pulse therapydrug withdrawaldysarthriaelectroencephalogramelectroencephalographyepilepsyepileptic dischargeepisodic ataxia type 2exonfaintnessfamily historyfebrile convulsionfemalefeverfocal epilepsyfollow upframeshift mutationgaze paralysisgene sequencehead movementhematuriahemiparesisheterozygoteHoffmann reflexhot flushhumanhyporeflexiaintroniron deficiency anemialearning disorderlimb weaknessmesencephalonmetabolic acidosismultiple sclerosisnauseanuclear magnetic resonance imagingnystagmuspaternal inheritanceperception disorderseizureslurred speechspastic gaitspasticityspeech disorderstop codonthoracic spinal cordvertigovisual acuityvisual evoked potentialvomitingwhite matterataxiacomplicationgeneticsmigraine with auramultiple sclerosisArticle10.1080/00207454.2020.1835896