Altinisik M.Delibay Y.Erdogan M.2024-07-222024-07-22202409273948http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11693Purpose: To describe an atypical presentation of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) in a patient with ankylosing spondylitis (AS) receiving secukinumab. Methods: Retrospective chart review. Results: A 48-year-old female patient with AS receiving secukinumab complained of impaired vision in her left eye. Left eye examination revealed multiple yellow-white lesions at the posterior pole and central subfoveal fluid.The lesions regressed without scarring. The case was diagnosed with clinically APMPPE. Conclusion: In AS patients, posterior uveitis can manifest as APMPPE. It should be recorded as an entity to be considered in the differential diagnosis. © 2023 Taylor & Francis Group, LLC.EnglishAcute DiseaseAntibodies, Monoclonal, HumanizedFemaleFluorescein AngiographyHumansMiddle AgedPigment Epithelium of EyeRetrospective StudiesSpondylitisSpondylitis, AnkylosingWhite Dot SyndromesetanerceptHLA B27 antigeninfliximabmethotrexatesecukinumabsteroidmonoclonal antibodysecukinumabacute posterior multifocal placoid pigment epitheliopathyadultankylosing spondylitisautofluorescencebest corrected visual acuityblurred visioncase reportclinical articledifferential diagnosisdrug withdrawaleyeeye examinationfemalefluorescence angiographygenetic screeninghumanintraocular pressureLettermiddle agedmultimodal imagingoptical coherence tomographyretrospective studysubretinal fluidthorax radiographyuveitisvisual impairmentacute diseaseankylosing spondylitispathologypigment epitheliumspondylitiswhite dot syndromeLetter10.1080/09273948.2022.2150225