Yilmaz Ovali G.Ersoy B.Tuncyurek O.Urk V.Ozkol M.Ozhan B.Baser E.Pabuscu Y.2024-07-222024-07-22200801688227http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19171Aim: We aimed to investigate the retrobulbar blood circulation using Colour Doppler Imaging (CDI) in type 1 diabetic children and adolescents who had no diabetic retinopathy and to compare the results with their healthy peers. Methods: Forty-nine patients with type 1 diabetes mellitus with no retinopathy on fundoscopic examination were included in the study. Forty-nine healthy children were defined as the control group. Central retinal artery (CRA), ophthalmic artery (OA) and posterior ciliary artery (PCA) were examined with Doppler US bilaterally. Peak systolic velocity (PSV), end diastolic velocity (EDV) and resistive indices (RI) for each artery were recorded. Results: Blood flow velocity of the OA was significantly different in diabetic patients (p < 0.05). EDV of the OA was significantly higher (p = 0.011) and RI was significantly lower (p = 0.027) in patients with diabetes duration of longer than 5 years. RI of the CRA was significantly higher in patients who had higher microalbuminuria levels (p = 0.016). Conclusion: EDV of the OA increases and RI of the OA decreases in diabetes duration longer 5 years. Raised AER increases RI of the CRA. These findings may be the initial changes in the arterial circulation before vascular rigidity develops. © 2007 Elsevier Ireland Ltd. All rights reserved.EnglishAdolescentChildDiabetes Mellitus, Type 1Diabetic RetinopathyHemodynamicsHumansReference ValuesRetinal ArteryRetinal VeinUltrasonography, Doppleradolescentadultarticleblood flow velocitychildciliary arterycirculationclinical articlecontrolled studydiabetic retinopathydisease durationDoppler flowmetryflow ratehemodynamicshumaninsulin dependent diabetes mellitusmetabolic regulationmicroalbuminuriaophthalmic arteryophthalmoscopyretina arteryretina blood flowDoppler ultrasonography imaging of hemodynamic alteration of retrobulbar circulation in type 1 diabetic children and adolescents without retinopathyArticle10.1016/j.diabres.2007.09.001