Parlak Y.Gumuser G.Sayit E.2024-07-222024-07-22201501448420http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/16403The aim of this study was to determine the excretion of Samarium-153-ethylenediaminetetramethylphosphonic acid (153Sm- EDTMP) in urine and to calculate the dose rate of its retention in the body as a function of time and the dose received by the skin of laboratory staff 's finger. Urine samples were collected from 11 patients after intravenous injection of 153Sm-EDTMP. The measurements of dose rate were performed. Thermoluminescent dosemeters were used for absorbed dose measurements. Effective half-lives that were calculated from urine sample measurements were found as 7.1±3 h within the first 24 h. Whole body dose rates before collecting urine of patients were 60.0 ± 15.7 μSv h21 for within 1 h following 153Sm-EDTMP administration. The highest finger radiation dose is to the right-hand thumb (3.8 ± 2 mGy). The results of the study imply that patients who recieved 153Sm-EDTMP therapy should be kept a minumum of 8 h in an isolated room at hospital and that one staff should give therapy at most two patients per week. © The Author 2014.EnglishAgedAnalgesics, Non-NarcoticBone NeoplasmsHumansMaleMetabolic Clearance RateMiddle AgedOccupational ExposureOrganometallic CompoundsOrganophosphorus CompoundsProstatic NeoplasmsRadiation DosageRadiopharmaceuticalsSkinTissue Distributionanalgesic agentorganometallic compoundorganophosphorus compoundradiopharmaceutical agentsamarium ethylenediaminetetramethylenephosphonateagedanalysisBone Neoplasmshumanmalemetabolic clearance ratemetabolismmiddle agedoccupational exposurepathologyProstatic Neoplasmsradiation doseradiation responsesecondaryskintissue distributionurineArticle10.1093/rpd/ncu237