Mütevelizade G.Sezgin C.Gümüşer G.Sayit E.2024-07-222024-07-22202221461414http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/12564Prostate-specific membrane antigen (PSMA) is a transmembrane protein with overexpression in most prostate cancer cells. Gallium-68-(68Ga) PSMA positron emission tomography/computed tomography (PET/CT) imaging is a game-changer in the management of prostate cancer.68Ga PSMA PET/CT scan is advanced and a promising radioligand has high sensitivity in determining lesions of prostate cancer with a high tumor to background ratio. The most common areas of metastasis are the bone and pelvic lymph nodes. The prognosis of prostate cancer is mainly determined by the status of metastases. The presence and the localization of metastases affects treatment planning. In our cases, we presented some examples of uncommon sites of metastases such as the brain, adrenal glands, penis and orbit. Improvements in imaging techniques, such as68Ga PSMA PET/CT have led to the possibility to make more determination of rare metastase sites in prostate cancer patients. © 2022 by Turkish Society of Nuclear Medicine Molecular Imaging and Radionuclide Therapy published by Galenos Yayınevi.EnglishAll Open Access; Gold Open Accessgallium 68lutetium 177prostate specific membrane antigenradioisotopeadultandrogen deprivation therapyArticlebrain hemorrhagebrain metastasiscancer localizationcase reportcastration resistant prostate cancerclinical articlecolor Doppler flowmetryhumanmalemetastasismiddle agedorbit metastasispelvis lymph nodepositron emission tomography-computed tomographyposttraumatic intracranial bleedingprostate adenocarcinomaprostate cancervery elderlyArticle10.4274/mirt.galenos.2021.41033