Mavioğlu H.Kisabay A.Sari S.Akçali S.Oktan B.2024-07-222024-07-22201613001817http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/16092Miller Fisher Syndrome (MFS) is a rare variant of Gulliain Barre syndrome (GBS) characterized by external ophthalmoplegia, ataxia, areflexia, and usually by positive anti GQ1b antibody. It occurs through an autoimmune mechanism most frequently after Campylobacter jejuni, followed by Haemophilus influenzae infection. Although occurrence with other viruses and bacteria has been reported, the concurrence of MFS and Human Herpes Virus-6 (HHV-6) has not been reported so far. There are a few publications reporting association of GBS with HHV-6. In the present study, HHV-6 DNA with PCR was detected in the cerebrospinal fluid (CSF) of a 59 year-old female patient diagnosed with MFS/pharyngeal-cervical-brachial variant of GBS overlap from clinical findings and positive anti-GQ1b antibody in the serum. This article aims to create awareness of a possible relationship between MFS, GBS and HHV-6. © 2016, Ege University Press. All right reserved.Englishganglioside GQ 1b antibodyimmunoglobulinvirus DNAadultArticlecase reportcerebrospinal fluid analysisdysphagiaexternal ophthalmoplegiafacial nerve paralysisfemaleGuillain Barre syndromehand paresthesiaherpes virus infectionhumanHuman herpesvirus 6hypernasalityhypesthesiamiddle agedpharyngeal cervical brachial variant of Guillain Barre syndromeprotein cerebrospinal fluid levelptosisrespiratory failurevertebrobasilar insufficiencyArticle