Ince A.Maviog̈lu H.Eser E.2024-07-222024-07-22201113021664http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18094Objectives: The aim of the present study is to assess the validity and reliability of Turkish adaptation of the Alzheimer Disease Cooperative Study-Activities of Daily Living (ADCSADL) scale and to enable the use of this scale in Turkey in Alzheimer Disease (AD) related studies. Material and Method: Thirty-two patients with AD, 10 suspicious demented patients (mild cognitive impairment) and 31 non-demented control subjects with similar age, gender and educational status were enrolled to the study. ADCS-ADL, Modified Older Americans Resources and Services Procedures Instrument (MOARSI), Mini Mental State Examination(MMSE), Clinical Dementia Rating (CDR) and Global Deterioration Scale(GDS) were applied to all subjects. Alzheimer Disease Assessment Scale-Cognitive Scale (ADAS Cog) was also applied to the demented and suspicious demented subjects. Internal consistency, test-retest reliability, differential validity and concurrent validity were statistically analyzed. Findings: ADCS-ADL differentiated AD group from normal and suspicious demented groups significantly (p: 0.0001). Additionally, the scale was found sensitive to dementia stages (p: 0.01). A significant correlation between the ADCS-ADL scores of AD group and MMSE(r: 0.736), CDR (r: 0.758), CDR Total (r: 0.828), GDS (r: 0.743), basic section of MOARSI (r:0.826) and instrumental section of MOARSI (r:0.826) groups were detected. The correlation with ADAS-Cog was weak (r: 0.191). Internal consistency values were measured as α: 0.937, 0.719 and 0.758 for AH, suspicious demented and control groups respectively. Test-retest reliability was quite high (ICC: 0.998). Conclusion: The study showed that Turkish adaptation of ADCS-ADL is valid and reliable scale in assessing and monitoring the AD patients in Turkish society.TurkishagedAlzheimer diseaseAlzheimer Disease Assessment Scale-Cognitive ScaleAlzheimer Disease Cooperative Study-Activities of Daily Living scalearticleclinical articleClinical Dementia Ratingcognitive defectdementiadisease severityeducational statusfemaleglobal deterioration scalehumaninternal consistencymalemini mental state examinationModified Older Americans Resources and Services Procedures Instrumentrating scaletest retest reliabilityTurkey (republic)validation studyArticle