Öztürk F.Sobaci G.Sami Ilker S.Can C.2024-07-222024-07-22200115304086http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20471Clinical and histologic effects of topical recombinant α-interferon (IFN), systemic IFN, topical dexamethasone, and dexamethasone plus topical IFN on corneal neovascularization in response to silver nitrate cauterization were investigated in 110 eyes of 60 Wistar rats. The eyes were evaluated according to the burn stimulus, neovascularization, and histologic inflammation grades 5 days after cauterization. Antineovascular effects of topical and systemic IFN were significantly greater than a placebo but less than dexamethasone alone or in combination with IFN.Englishdexamethasoneplaceborecombinant alpha interferonsilver nitrateanimal cellanimal tissuearticleburncauterizationcontrolled studycornea neovascularizationcornea perforationdrug effectdrug mechanisminflammationnecrosisnonhumanratArticle10.1007/s12009-001-0070-5