Karadeniz G.Buyukyazi G.Gunduz T.Kutlu N.Ozbakkaloglu B.2024-07-222024-07-22200202559625http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20367The aim of this study was to determine the effect of chronic exercise on immune functions. Eighteen postmenopausal women were included in the study: nine were undertaking chronic exercise (exercise group) and the other nine were sedentary (control group). The exercise group had been training for 7.2 h per week for 19.9 years. The subjects were chosen among postmenopausal women to eliminate any effects of menstrual cycle on the immune system. The subjects were paired and reported to the Human Performance Laboratory twice a week between 8:00 and 10:00 a.m. In the first visit, body composition and aerobic capacity were measured. In the second visit, their blood samples were drawn and screened immediately. VO2max was significantly higher in the exercise group. The leukocyte and lymphocyte subset data comparions demonstrated no significant difference between the exercise group and the control group. Only IgA was significantly higher in the exercise group than in the control group (p = 0.005). The results of this investigation indicate that chronic exercise training does not significantly alter concentrations of T and B lymphocytes or T lymphocyte subsets. However, a significant increase in IgA levels may occur, leading to changes in immune response.Englishimmunoglobulin Aoxygenadultaerobic capacityagedarticleB lymphocyteblood analysisblood samplingbody compositioncell countclinical articlecontrolled studyexercise testfemalehumanhuman cellimmune responseimmunoglobulin blood levelleukocytelymphocyte subpopulationoxygen concentrationphysical performancepostmenopausestatistical significanceT lymphocyteArticle