Gurboga B.Tuncgovde E.B.Kemiklioglu E.2024-07-222024-07-22202200063592http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/12798Liquid crystal elastomers (LCEs) play role in tissue engineering investigations, with the combination of orientational ordering generated by liquid crystal (LC) moieties and the elastic capabilities of polymers. Liquid crystal-based polymer materials require a thorough understanding of their features that set them apart from other smart materials for proper design and application. LCEs offer many advantages for their widespread use in the field of biomaterials, by virtue of their simplicity of processing, anisotropic behavior, and responding to numerous external stimuli. Especially, LCEs have widespread usage in bioengineering applications such as scaffolds due to their biocompatibility, viability, and proliferation properties of these materials. This study introduces a brief overview of the new areas of liquid crystal-based elastomer applications combining both biomaterials and engineering. © 2022 Wiley Periodicals LLC.EnglishBiocompatible MaterialsElastomersLiquid CrystalsTissue EngineeringBiocompatibilityElastomersPlasticsScaffolds (biology)Tissueacetonebiomaterialbutylaminechloroformelastomereosinhematoxylinn,n dimethylformamidenanomaterialphotoinitiatorpolymertetrahydrofuranAnisotropic behaviorsDesign and applicationEngineering investigationsExternal stimulusLiquid crystal elastomersLiquid-crystalsOrientational ordersPolymer materialsProper designTissues engineeringsannulus fibrosuscell proliferationconfocal microscopydifferential scanning calorimetrydrug delivery systemhistologyhumanintervertebral diskliquid crystalMasson stainingmicroemulsionnonhumanpolarization microscopyReviewrobocastingscanning electron microscopythree dimensional printingtissue engineeringviscositychemistrytissue engineeringLiquid crystalsReview10.1002/bit.28038