Türkkani, GGüngör, BCetin, OIçhedef, ÇParlak, YGümüser, FGBilgin, BESTeksöz, S2024-07-182024-07-181588-2780http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/6896SPRINGERArticleIn this study, it is aimed to design a smart drug delivery system for the diagnosis and treatment of cancer cells. Magnetic-solid lipid nanoparticles were synthesized as a drug delivery system and azathioprine (AZA) was loaded into this system. This newly created system was radiolabeled using technetium-99 m with a radiolabeling yield of 90.3%. Drug loading into the SLMNP was found as 86%. The biological behavior of Tc-99m and radiolabeled magnetic solid lipid nanoparticles loaded with azathioprine (Tc-99m-AZA-SLMNP) was investigated in vitro and in vivo.DELIVERY