Browsing by Author "Çakiroglu, E"

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    The effect of emotion recognition and mindfulness on depression symptoms: A case-control study
    (CAMBRIDGE UNIV PRESS) Aydin, O; Tvrtkovic, S; Çakiroglu, E; Ünal-Aydin, P; Esen-Danaci, A
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    Cerebral Venous Thrombosis: A Case Series and Literature Review
    (AVES) Kisabay, A; Çakiroglu, E; Selçuki, D
    In this study, 15 patients who were being followed in a cerebrovascular diseases outpatient clinic with the diagnosis of cerebral venous thrombosis were retrospectively reviewed. The study aimed to assess and review their complaints at the time of presentation and during the clinical course as well as assess the etiological risk factors using new imaging modalities and new and old therapeutic modalities. Cerebral venous thrombosis was recognized as a rare and fatal condition when it was first defined; however, it currently presents with a better prognosis because of increased awareness, advanced neuroimaging techniques, and therapeutic methods. The use of dabigatran, which is a new therapeutic option, remains on the agenda particularly for avoiding drug interaction with warfarin in the patients with comorbidities and history of multiple medications. Dabigatran has a high rate of success with low incidence of side effects.
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    Evaluation of microRNA expression levels during the craving period of patients diagnosed with severe alcohol use disorder
    (TAYLOR & FRANCIS INC) Asçibasi, K; Deveci, A; Özyilmaz, B; Erdogan, KM; Çakiroglu, E
    BackgroundThe aim of this study is to compare the serum MicroRNA (miRNA) expression levels on the first day of hospitalization and at the end of the first month of treatment in patients with alcohol use disorder and severe craving symptoms. Through the obtained data, biological agents targeting microRNA for alcohol craving may be developed.MethodsThe volunteer group consists of four patients diagnosed with severe alcohol use disorder. Sociodemographic and Clinical Information Form, DSM-5 Structured Clinical Interview-Clinical Version (SCID-5-CV), Penn Alcohol Craving Scale (PACS) were used as clinical assessment tools. Peripheral blood samples were obtained at the time of application and on the 30th day. miRNA isolation was performed. The expression levels of 2578 different mature human miRNAs were measured.ResultsThe miRNAs showing statistically significant differences in peripheral blood samples taken on the 1st and 30th days from alcohol users are as follows: miR-19a-3p, miR-6849-5p, miR-6726-5p, miR-6848-5p, miR-186-5p, miR-6889-5p, miR-933, miR-370-3p, miR-5739, miR-103a-2-5p, miR-6860, miR-1254, miR-1260a, miR-3921, miR-127-3p, miR-8064, miR-6870-5p, miR-4688ConclusionsA significant difference was found between the 1st and 30th days in 18 of 2578 miRNAs scanned. It is aimed to investigate these 18 miRNAs in larger sample groups during the alcohol craving period.