Browsing by Author "Çetin I."

Now showing 1 - 3 of 3
  • No Thumbnail Available
    Item
    Anesthesia management in a patient with scleroderma during coronary artery bypass grafting; [Sklerodermali hastada koroner arter cerrahisi sirasinda anestezi yönetimi]
    (2007) Ok G.; Erbüyün K.; Tok D.; Çetin I.; Şirin H.
    Systemic sclerosis is an autoimmune connective tissue disease, characterized by microvascular occlusive disease with vasospasm, intimal proliferation, cutaneous and parenchymal fibrosis. Anesthesiologists managing patients intraoperatively must be knowledgeable about the pathogenesis, clinical manifestations, system involvement, and anesthetic considerations for the progressive systemic sclerosis surgical patient. The anesthesiologist should understand these complex pathophysiological processes so as to minimize potential risks. We report a 69 year old female patient with systemic sclerosis operated for coronary artery disease.
  • No Thumbnail Available
    Item
    The effects of esmolol on anesthetic and analgesic requirement; [Esmololün anestezik ve analjezik gereksinimi üzerine etkisi]
    (2007) Topçu I.; Öztürk T.; Taşyüz T.; Işik R.; Çetin I.; Sakarya M.
    Aim: There are many adjuvant agents which decrease the need of anesthetic and analgesic drugs during general anesthesia management. The comparison of the effects of esmolol, a β1 receptor antagonist with a ultra-short-acting, is aimed upon the consumption of analgesic, anesthetic and neuromuscular blocker drugs in this randomized, double-blinded study. Materials and Methods: 18-70 year old, ASA I-II, 60 patients scheduled for elective abdominal operations under general anesthesia were equally divided into 2 groups. In Group E; 1 mg kg-1 esmolol infusion was started slowly prior to induction and 250 μg kg-1 min-1 esmolol infusion lasted during the operation, in Group C (control group) isotonic solution was administered in the same volume. Propofol (due to BIS values) and remifentanil (due to heart beat rate and blood pressure) were administered by TIVA in anesthesia maintenance to the patients. Rocuronium was used as a neuromuscular blocker drug. All hemodynamics values of the cases, the amounts of the anesthetic consumption, analgesic and neuromuscular blocker drugs before and after induction were recorded. Results: There was no difference for age, gender, type and period of operation and induction doses between the groups (p>0.05). The need of analgesic and anesthetic drug was decreased but the consumption of neuromuseular blocker drug not affected in Group E than Group K (p<0.05). Mean arterial blood pressure and heart beat rate variables were more stabile in the perioperative period in Group E. The hemodynamic response to intubation and extubation were reduced by esmolol infusion. Conclusion: The results suggest that the perioperative esmolol administration may reduce intraoperative requirement of the anesthetics and the analgesic to prevent acute autonomic responses during anesthesia and surgery.
  • No Thumbnail Available
    Item
    The effects of lornoxicam on brain edema and blood brain barrier following diffuse traumatic brain injury in rats; [Lornoksikamin siçanlarda diffüz travmatik beyin hasarinda beyin ödemi ve kan beyin bariyeri üzerine etkileri]
    (Turkish Association of Trauma and Emergency Surgery, 2013) Topçu I.; Gümüşer G.; Bayram E.; Aras F.; Çetin I.; Temiz C.; Çivi M.
    BACKGROUND In this experiment, the effects of lornoxicam on brain edema and the blood brain barrier (BBB) following diffuse traumatic brain injury (TBI) were studied. METHODS Twenty adult male Wistar albino rats were anesthetized, and experimental closed head trauma was induced by the Marmarou method. After head injury, the rats were randomly divided into two groups: Group I was the control group, to which 2 ml saline was administered intraperitoneally, and Group II was the lornoxicam group, to which 2 ml 1.3 mg kg-1 lornoxicam was administered intraperitoneally. Twenty-four hours after head trauma, 99 mTc pentetate (DTPA) was injected at a dose of 37 MBq, and posterior planar images of each rat were obtained using an Infinia gamma camera. After imaging of BBB permeability, brain tissues were dissected from the cranium. The brain water content (BWC) of each sample was calculated using the wet-dry method. RESULTS The lesion/background (L/b) ratio of Group I was 3.76±0.46 and 3.02±0.66 for early (5th min) and late (60th min) imaging, respectively. In Group II, the L/b ratios were 3.52±0.96 and 2.63±0.63 for early and late imaging, respectively (p>0.05). BWC was 79.6±2.5% and 77.5±1.1% for Groups I and II, respectively (p<0.05). CONCLUSION In this rat model of TBI, lornoxicam reduced brain edema but did not affect BBB permeability.