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  1. Home
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Browsing by Author "Örgüç, S"

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    THE ROLE OF DIFFUSION WEIGHTED IMAGING IN THE ASSESSMENT OF AXILLARY LYMPH NODES
    Basara, I; Örgüç, S; Coskun, T
    Objective: Several studies have shown that diffusion weighted imaging (DWI) can serve as a powerful tool for differentiating benign from malignant breast lesions. In addition to this use, DWI may also be used in the assessment of axillary lymph nodes, since they show similar tissue characteristics to the primary tumor. Materials and Methods: We applied dynamic contrast enhanced breast magnetic resonance imaging and DWI to 110 female patients and 214 breasts. Apparent diffusion coefficient (ADC) values of 187 lymph nodes (142 benign and 45 malignant) in 177 axillae were measured. Malignant lymph nodes were diagnosed histopathologically, benign lymph nodes were diagnosed clinically and with imaging findings. Results: The mean ADC values were 1.00x10-3 mm(2)/s for the malignant, and 1.39x10(-3) mm(2)/s for the benign lymph nodes. The ADC values of malignant lymph nodes were significantly lower than the benign ones (p=0.001). When 1.22x10(-3) mm(2)/s was accepted as the cut-off ADC value, a sensitivity of 75.6% and a specificity of 71.1% were detected. Conclusion: Our preliminary data suggest that ADC measurements might be useful in differentiating malignant from benign axillary lymph nodes in the preoperative period. Further studies on a larger scale will increase confidence in the results of DWI.
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    Computed Tomographic Reversal Sign in an Adult with Methanol Intoxication
    Tunçyürek, Ö; Tarhan, S; Örgüç, S; Atalar, M; Sener, RN
    The computed tomographic (CT) reversal sign is associated with diffuse, anoxic/ischemic cerebral injury, and is seen almost exclusively in children, and only one adult patient with meningitis exists in the literature with this sign. On the other hand, methyl alcohol intoxication is usually associated with bilateral putaminal necrosis, and no CT reversal sign has been observed before in this condition. This report presents an adult patient with methyl alcohol intoxication, and the CT reversal sign.
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    Tumor-like Lesions of Bone and Soft Tissues and Imaging Tips for Differential Diagnosis
    Örgüç, S; Arkun, R
    In the musculoskeletal system, tumor-like lesions may present similar imaging findings as bone and soft tissue tumors and can be defined as tumors on radiologic examinations. Misinterpretation of the imaging findings can lead to inappropriate clinical management of the patient. There is still some debate regarding the pathophysiology and origin of tumor-like lesions that include congenital, developmental, inflammatory, infectious, metabolic, reactive, posttraumatic, post-therapeutic changes, and some miscellaneous entities causing structural changes. Although tumor-like lesions are historically defined as non-neoplastic lesions, some of them are classified as real neoplasms. We discuss a spectrum of entities mimicking tumors of bone and soft tissues that include various non-neoplastic diseases and anatomical variants based on imaging findings.
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    Contribution of Kinetic Characteristics of Axillary Lymph Nodes to the Diagnosis in Breast Magnetic Resonance Imaging
    Örgüç, S; Basara, I; Pekindil, G; Coskun, T
    Objective: To assess the contribution of kinetic characteristics in the discrimination of malignant-benign axillary lymph nodes. Material and Methods: One hundred fifty-five female patients were included in the study. Following magnetic resonance imaging (MRI) examinations post-processing applications were applied, dynamic curves were obtained from subtracted images. Types of dynamic curves were correlated with histopathological results in malignant cases or final clinical results in patients with no evidence of malignancy. Sensitivity, specificity, positive likehood ratio (+LHR), negative (-LHR) of dynamic curves characterizing the axillary lymph nodes were calculated. Results: A total of 178 lymph nodes greater than 8 mm were evaluated in 113 patients. Forty-six lymph nodes in 24 cases had malignant axillary involvement. 132 lymph nodes in 89 patients with benign diagnosis were included in the study. The sensitivity of type 3 curve as an indicator of malignancy was calculated as 89%. However the specificity, +LHR, -LHR were calculated as 14%, 1.04, 0.76 respectively. Conclusion: Since kinetic analysis of both benign and malignant axillary lymph nodes, rapid enhancement and washout (type 3) they cannot be used as a discriminator, unlike breast lesions. MRI, depending on the kinetic features of the axillary lymph nodes, is not high enough to be used in the clinical management of breast cancer patients.
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    Methanol poisoning with necrosis corpus callosum
    Keles, GT; Örgüç, S; Toprak, B; Özaslan, S; Sakarya, M
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    Ewing's sarcoma metastasis into the breast
    Örgüç, S; Basara, I; Poçan, T; Özgüven, AA; Özkol, M
    The metastasis of extramammary malignancies into the breast is very unusual. Lymphoma, malignant melanoma, and rhabdomyosarcoma are the most common tumors that metastasize into breast tissue. The histological spectrum of breast masses in children and adolescents is different from that of adults. Imaging findings are useful for performing a diagnosis, but in a patient with a known malignancy, any enlarging breast mass, even one with a benign radiological appearance, should be investigated with a biopsy. In this article, we present the imaging findings of a 12-year-old female patient with breast metastasis of Ewing's sarcoma.
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    Axillary Schwannoma Mimicking Lymphadenopathy: Two Different Case Reports
    Örgüç, S; Basara, I; Özkarakas, P; Poçan, T; Aydede, H
    Schwannomas are essentially benign tumors originating from schwann cells of peripheral, cranial or sympathetic nerves. They are not aggressive, encapsulated and grow slowly. Malignant transformation can rarely be seen. Even though they can be localized in any where in the body, cutaneous nerves of the head-neck region and flexor parts of the extremities are most commonly involved. Schwannomas are usually solitary, however multiple schwannomas can rarely be seen in the peripheral nervous system including cranial nerves, spinal nerve roots, brachial-lumbosacral plexus and peripheral nerves. In these two cases, we aimed to report ultrasonography (US), magnetic resonance imaging (MRI) and pathology findings of different axillary schwannomas mimicking lymphadenopathy, and discuss the differential diagnosisin the light of the literature. In these patients, the lesions were noted to be in direct continuity with a cord-like structure resembling a nerve. US and MRI findings were compatible with the literature. Radiologic findings were confirmed by pathologic examination. As seen in our cases, a detailed differential diagnosis should be considered in every axillary lesion including frequently seen axillary lymphadenopathies.
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    Dupuytren's Contracture With Rare Bilateral Thumb and Little Finger Involvement Demonstrated by Ultrasound Elastography
    Ulusoy, A; Tikiz, C; Örgüç, S
    Dupuytren's contracture is a disease that affects the functionality of the hand and causes contractures leading to progressive fibrosis of the palmar fascia. Dupuytren's contracture usually affects the fourth and fifth digits, but thumb involvement is rare. In this article, we presented a rare case of Dupuytren's contracture with bilateral thumb and fifth digit involvement in a 77-year-old male patient who was assessed by ultrasound elastography and gained range of motion after rehabilitation.
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    Single voxel in vivo proton magnetic resonance spectroscopy of breast lesions: experience in 77 cases
    Basara, I; Örgüç, S; Coskun, T
    PURPOSE We aimed to determine the value of in vivo single voxel proton magnetic resonance spectroscopy (MRS) in characterizing breast lesions. MATERIALS AND METHODS Breast MRS was performed in 77 patients. Choline resonance peak at 3.2 parts per million (ppm) was defined positive when it was at least two times higher than baseline. MRS findings were compared with the final diagnosis of cases for two different values (3.23 and 3.28 ppm). RESULTS Thirty-one malignant and 13 benign lesions had choline peaks. Sensitivity was 84%, specificity was 64%. Positive likelihood ratio (LHR) was 2.32, negative LHR was 0.25. Twenty-two malignant and 5 benign lesions had a peak at 3.23 ppm. Nine malignant and 8 benign lesions had a peak at 3.28 ppm. When 3.23 ppm was accepted as positive; sensitivity, specificity, and positive and negative LHRs were 79%, 82%, 4.4, and 0.26, respectively. CONCLUSION MRS provides additional parameters on evaluation of breast lesions. However, MRS of breast has some false negative results, thus it is still insufficient in clinical diagnosis.
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    Three-dimensional vascular mapping of the breast by using contrast-enhanced MRI: association of unilateral increased vascularity with ipsilateral breast cancer
    Örgüç, S; Basara, I; Coskun, T; Pekindil, G
    PURPOSE We aimed to retrospectively compare three-dimensional vascular maps of both breast obtained by dynamic magnetic resonance imaging (MRI) and determine the association of one-sided vascular prominence with ipsilateral breast cancer. MATERIALS AND METHODS MRI was performed using gadolinium in 194 cases. Two readers scored vascular density using maximum intensity projections (MIPs). Dynamic fat-saturated T1-weighted gradient-echo MIPs were acquired. Two readers evaluated the MIPs, and vessels greater than 2 mm in diameter and longer than 3 cm were counted. The difference in vessel numbers detected in the two breasts determined the score. RESULTS A total of 54 patients had malignant lesions (prevalence, 28%), including invasive ductal carcinoma (n=40), invasive mixed ductal-lobular carcinoma (n=5), invasive lobular carcinoma (n=3), ductal carcinoma in situ (n=3), mucinous carcinoma (n=1), medullary carcinoma (n=1), and leukemic metastasis (n=1). In 62 patients, there were benign lesions (fibroadenomas, fibrocysts), and four patient had inflammation (granulomatous mastitis in two patients, breast tuberculosis in two patients). There were 78 normal cases. When a difference of at least two vessels was scored as vascular asymmetry, the sensitivity, specificity, positive likelihood ratio (+LR), and negative (-LR) of unilaterally increased vascularity associated with ipsilateral malignancy were 69%, 92%, 8.72, and 0.34, respectively. When four infection and three post-operative cases with vascular asymmetry were excluded; prevalence, specificity, and +LR increased to 29%, 97%, and 22.8, respectively, with the same sensitivity and -LR. Differences in mean vascularity scores were evaluated with regard to tumor size. T1 and T2 tumors were not significantly different from each other. The mean score of T3 tumors differed significantly from T1 and T2 tumors. CONCLUSION MRI vascular mapping is an effective method for determining breast tissue vascularization. Ipsilateral increased vascularity was commonly associated with malignant breast lesions.
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    A case of mycetoma successfully treated with itraconazole and co-trimoxazole
    Gündüz, K; Örgüç, S; Demireli, P; Inanir, I; Sürücüoglu, S; Ovali, GY
    A 29-year-old woman with swelling, multiple nodules and discharging sinuses of her right foot is presented. A single nodule on the sole was excised 15 years ago and since then she has had recurrent attacks of swelling and discharging sinuses that improved partially with antibiotics. Magnetic resonance images (MRI) revealed an ill-defined mass predominantly with low signal intensity on T2W images. Within the granulomata, multiple unenhancing foci, with low T1W and T2W signal most likely representing the fungal balls or grains were detected. Histopathological examination revealed large clusters of microorganisms resembling fungal hyphae and bacteria, which were surrounded by mixed inflammatory infiltrate cells and stained positively by PAS and Gomori's methenamine silver stain. As minimal regression was seen on MRI with 4 months' itraconazole (200 mg day(-1)) treatment, co-trimoxazole (160 TMP/800 SMX b.i.d.) was added to treatment. Complete remission was established by MRI examination after 10 months with this combination therapy.
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    A rare cause for a gluteal pain in adults: tuber ischium avulsion fracture
    Tikiz, C; Örgüç, S; Ulusoy, A; Akgul, Ö
    Tuber ischium avulsion fracture is a rare injury, of which the diagnosis is often missed or delayed. It usually occurs as a result of hamstring muscle contraction in adolescent athletes. Herein, we report a tuber ischium avulsion fracture developed in a 28-year-old male patient, who was admitted with the complaint of pain in the gluteal area after inguinal hernia surgery.
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    RADIOLOGICAL FINDINGS OF CHRONIC MOREL LAVALLEE SYNDROME: CASE REPORT
    Örgüç, S; Basara, I; Özkarakas, P; Yoleri, L
    Morel Lavallee Syndrome is defined as a soft tissue injury consisting of a closed internal degloving of the subcutaneous tissue creating a cavity filled with bloody serous liquid. This syndrome is usually not recognized by general or orthopedic surgeons and is therefore frequently missed or diagnosed late. If Morel Lavallee Syndrome is clinically misdiagnosed, findings appear as a chronic growing painful mass. With these symptoms, it can mimic hemangioma, synovial sarcoma, post traumatic fat necrosis or hematoma. However, if there is a history of trauma, characteristic magnetic resonance imaging findings can be helpful in the diagnosis of these cases. In the literature, sporadic cases have been reported without a clear etiopathogenic explanation.
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    FINDINGS OF EXTENSIVE COSTAL AND STERNAL METASTASIS OF A PATIENT WITH BREAST CARCINOMA BY DYNAMIC, DIFFUSION WEIGHTED AND THREE DIMENSIONAL BREAST MAGNETIC RESONANCE IMAGING
    Örgüç, S; Basara, I; Aras, F
    Breast magnetic resonance imaging (MRI) is used in local staging of breast carcinoma with high sensitivity and accuracy. During this technique bony structures of the thorax such as sternum and anterior ribs are also evaluated. Direct graphy and computed tomography are not diagnostic in the patients with costal metastasis which have medullary bone infiltration without pathological fracture. Dynamic breast MRI can determine bone metastasis without cortical destruction. Especially multiplanary maximum intensity projection (MIP) images which are obtained from postcontrast substructed images are helpful in determining bone metastasis. Coronal MIP images can show infiltration of bony costas. Chondromateus costas are usually preserved. Bone syntigraphy is accepted as the gold standard for determining bone metastasis, however the spatial resolution of MRI is higher than scintigraphy. In breast carcinoma cases, bone, pleura, peritonum and liver metastasis are seen commonly and these localizations must be evaluated carefully with breast MRI. MIP and diffusion weighted images provide diagnostic contributions.
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    Soft tissue tumor imaging in adults: European Society of Musculoskeletal Radiology-Guidelines 2024: imaging immediately after neoadjuvant therapy in soft tissue sarcoma, soft tissue tumor surveillance, and the role of interventional radiology
    Noebauer-Huhmann, IM; Vilanova, JC; Papakonstantinou, O; Weber, MA; Lalam, RK; Nikodinovska, VV; Sanal, HT; Lecouvet, FE; Navas, A; Martel-Villagran, J; de Rooy, JWJ; Fritz, J; Verstraete, K; Grieser, T; Szomolanyi, P; Chaudhary, S; Sconfienza, LM; Tagliafico, AS; Afonso, PD; Albtoush, OM; Aringhieri, G; Arkun, R; Aström, G; Bazzocchi, A; Botchu, R; Breitenseher, M; Dalili, D; Davies, M; de Jonge, MC; Mete, BD; Gielen, JLMA; Hide, G; Isaac, A; Ivanoski, S; Mansour, RM; Mccarthy, C; Muntaner-Gimbernat, L; O'Donnell, P; Örgüç, S; Rennie, WJ; Resano, S; Robinson, P; Ter Horst, SAJ; van Langevelde, K; Wörtler, K; Koelz, M; Panotopoulos, J; Windhager, R; Fueger, BJ; Schmid, M; Vanhoenacker, FM
    ObjectivesAn update of the first European Society of Musculoskeletal Radiology (ESSR) consensus on soft tissue tumor imaging in 2015 became necessary due to technical advancements, further insights into specific entities, and the revised WHO classification (2020) and AJCC staging system (2017). The third part of the revised guidelines covers algorithms and techniques beyond initial imaging: (1) Imaging after neoadjuvant therapy in soft tissue sarcoma, (2) sarcoma surveillance, and (3) special aspects, including surveillance of non-malignant entities and the role of interventional radiology.Materials and methodsA validated Delphi method based on peer-reviewed literature was used to derive consensus among a panel of 46 specialized musculoskeletal radiologists from 12 European countries. Statements that had undergone interdisciplinary revision were scored online by level of agreement (0 to 10) during two iterative rounds that could result in either 'group consensus,' 'group agreement,' or 'lack of agreement.'ResultsThe three sections contain 47 statements with comments. Group consensus was reached in 91.5%, group agreement in 6.4%, lack of agreement in 2.1%. In sarcoma, imaging immediately after neoadjuvant therapy is pivotal for determining the therapy effects and for resection-planning; surveillance should include imaging at fixed grade- and type-dependent intervals. In general, MRI is the method of choice for loco-regional surveillance of soft tissue sarcomas, and chest CT to assess metastatic disease. Interventional radiology has a role, especially in oligometastatic disease, palliative tumor control and local recurrences.ConclusionStrategies for standardized soft tissue tumor imaging regarding therapy control, surveillance, and useful interventional procedures are provided.Key PointsQuestionAn ESSR consensus update on soft tissue tumor imaging regarding surveillance became necessary due to technical advancements, further entity-specific insights, and revised WHO- and AJCC-classifications.FindingsImaging immediately after neoadjuvant therapy in soft tissue sarcoma is pivotal. Post-therapeutic surveillance should include imaging at regular intervals, stratified for tumor grade and type.Clinical relevanceThe updated ESSR soft tissue tumor imaging guidelines aim to provide best practice expert consensus for standardized imaging, to support radiologists in their decision-making, and to improve examination comparability, both in individual patients and in future studies on individualized strategies.Key PointsQuestionAn ESSR consensus update on soft tissue tumor imaging regarding surveillance became necessary due to technical advancements, further entity-specific insights, and revised WHO- and AJCC-classifications.FindingsImaging immediately after neoadjuvant therapy in soft tissue sarcoma is pivotal. Post-therapeutic surveillance should include imaging at regular intervals, stratified for tumor grade and type.Clinical relevanceThe updated ESSR soft tissue tumor imaging guidelines aim to provide best practice expert consensus for standardized imaging, to support radiologists in their decision-making, and to improve examination comparability, both in individual patients and in future studies on individualized strategies.Key PointsQuestionAn ESSR consensus update on soft tissue tumor imaging regarding surveillance became necessary due to technical advancements, further entity-specific insights, and revised WHO- and AJCC-classifications.FindingsImaging immediately after neoadjuvant therapy in soft tissue sarcoma is pivotal. Post-therapeutic surveillance should include imaging at regular intervals, stratified for tumor grade and type.Clinical relevanceThe updated ESSR soft tissue tumor imaging guidelines aim to provide best practice expert consensus for standardized imaging, to support radiologists in their decision-making, and to improve examination comparability, both in individual patients and in future studies on individualized strategies.
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    Soft tissue tumor imaging in adults: European Society of Musculoskeletal Radiology-Guidelines 2023-overview, and primary local imaging: how and where?
    Noebauer-Huhmann, IM; Vanhoenacker, FM; Vilanova, JC; Tagliafico, AS; Weber, MA; Lalam, RK; Grieser, T; Nikodinovska, VV; de Rooy, JWJ; Papakonstantinou, O; Mccarthy, C; Sconfienza, LM; Verstraete, K; Martel-Villagrán, J; Szomolanyi, P; Lecouvet, FE; Afonso, D; Albtoush, OM; Aringhieri, G; Arkun, R; Aström, G; Bazzocchi, A; Botchu, R; Breitenseher, M; Chaudhary, S; Dalili, D; Davies, M; de Jonge, MC; Mete, BD; Fritz, J; Gielen, JLMA; Hide, G; Isaac, A; Ivanoski, S; Mansour, RM; Muntaner-Gimbernat, L; Navas, A; O'Donnell, P; Örgüç, S; Rennie, W; Resano, S; Robinson, P; Sanal, HT; Ter Horst, SAJ; van Langevelde, K; Wörtler, K; Koelz, M; Panotopoulos, J; Windhager, R; Bloem, JL
    ObjectivesEarly, accurate diagnosis is crucial for the prognosis of patients with soft tissue sarcomas. To this end, standardization of imaging algorithms, technical requirements, and reporting is therefore a prerequisite. Since the first European Society of Musculoskeletal Radiology (ESSR) consensus in 2015, technical achievements, further insights into specific entities, and the revised WHO-classification (2020) and AJCC staging system (2017) made an update necessary. The guidelines are intended to support radiologists in their decision-making and contribute to interdisciplinary tumor board discussions.Materials and methodsA validated Delphi method based on peer-reviewed literature was used to derive consensus among a panel of 46 specialized musculoskeletal radiologists from 12 European countries. Statements were scored online by level of agreement (0 to 10) during two iterative rounds. Either group consensus, group agreement, or lack of agreement was achieved.ResultsEight sections were defined that finally contained 145 statements with comments. Overall, group consensus was reached in 95.9%, and group agreement in 4.1%. This communication contains the first part consisting of the imaging algorithm for suspected soft tissue tumors, methods for local imaging, and the role of tumor centers.ConclusionUltrasound represents the initial triage imaging modality for accessible and small tumors. MRI is the modality of choice for the characterization and local staging of most soft tissue tumors. CT is indicated in special situations. In suspicious or likely malignant tumors, a specialist tumor center should be contacted for referral or teleradiologic second opinion. This should be done before performing a biopsy, without exception.Clinical relevanceThe updated ESSR soft tissue tumor imaging guidelines aim to provide best practice expert consensus for standardized imaging, to support radiologists in their decision-making, and to improve examination comparability both in individual patients and in future studies on individualized strategies.Key Points center dot Ultrasound remains the best initial triage imaging modality for accessible and small suspected soft tissue tumors.center dot MRI is the modality of choice for the characterization and local staging of soft tissue tumors in most cases; CT is indicated in special situations. Suspicious or likely malignant tumors should undergo biopsy.center dot In patients with large, indeterminate or suspicious tumors, a tumor reference center should be contacted for referral or teleradiologic second opinion; this must be done before a biopsy.Key Points center dot Ultrasound remains the best initial triage imaging modality for accessible and small suspected soft tissue tumors.center dot MRI is the modality of choice for the characterization and local staging of soft tissue tumors in most cases; CT is indicated in special situations. Suspicious or likely malignant tumors should undergo biopsy.center dot In patients with large, indeterminate or suspicious tumors, a tumor reference center should be contacted for referral or teleradiologic second opinion; this must be done before a biopsy.Key Points center dot Ultrasound remains the best initial triage imaging modality for accessible and small suspected soft tissue tumors.center dot MRI is the modality of choice for the characterization and local staging of soft tissue tumors in most cases; CT is indicated in special situations. Suspicious or likely malignant tumors should undergo biopsy. center dot In patients with large, indeterminate or suspicious tumors, a tumor reference center should be contacted for referral or teleradiologic second opinion; this must be done before a biopsy.
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    Soft tissue tumor imaging in adults: whole-body staging in sarcoma, non-malignant entities requiring special algorithms, pitfalls and special imaging aspects. Guidelines 2024 from the European Society of Musculoskeletal Radiology (ESSR)
    Noebauer-Huhmann, IM; Vanhoenacker, FM; Vilanova, JC; Tagliafico, AS; Weber, MA; Lalam, RK; Grieser, T; Nikodinovska, VV; de Rooy, JWJ; Papakonstantinou, O; Mccarthy, C; Sconfienza, LM; Verstraete, K; Martel-Villagran, J; Szomolanyi, P; Lecouvet, FE; Afonso, D; Albtoush, OM; Aringhieri, G; Arkun, R; Aström, G; Bazzocchi, A; Botchu, R; Breitenseher, M; Chaudhary, S; Dalili, D; Davies, M; de Jonge, MC; Mete, BD; Fritz, J; Gielen, JLMA; Hide, G; Isaac, A; Ivanoski, S; Mansour, RM; Muntaner-Gimbernat, L; Navas, A; O'Donnell, P; Örgüç, S; Rennie, WJ; Resano, S; Robinson, P; Sanal, HT; Ter Horst, SAJ; van Langevelde, K; Wörtler, K; Koelz, M; Panotopoulos, J; Windhager, R; Bloem, JL
    ObjectivesThe revised European Society of Musculoskeletal Radiology (ESSR) consensus guidelines on soft tissue tumor imaging represent an update of 2015 after technical advancements, further insights into specific entities, and revised World Health Organization (2020) and AJCC (2017) classifications. This second of three papers covers algorithms once histology is confirmed: (1) standardized whole-body staging, (2) special algorithms for non-malignant entities, and (3) multiplicity, genetic tumor syndromes, and pitfalls.Materials and methodsA validated Delphi method based on peer-reviewed literature was used to derive consensus among a panel of 46 specialized musculoskeletal radiologists from 12 European countries. Statements that had undergone interdisciplinary revision were scored online by the level of agreement (0 to 10) during two iterative rounds, that could result in 'group consensus', 'group agreement', or 'lack of agreement'.ResultsThe three sections contain 24 statements with comments. Group consensus was reached in 95.8% and group agreement in 4.2%. For whole-body staging, pulmonary MDCT should be performed in all high-grade sarcomas. Whole-body MRI is preferred for staging bone metastasis, with [18F]FDG-PET/CT as an alternative modality in PET-avid tumors. Patients with alveolar soft part sarcoma, clear cell sarcoma, and angiosarcoma should be screened for brain metastases. Special algorithms are recommended for entities such as rhabdomyosarcoma, extraskeletal Ewing sarcoma, myxoid liposarcoma, and neurofibromatosis type 1 associated malignant peripheral nerve sheath tumors. Satisfaction of search should be avoided in potential multiplicity.ConclusionStandardized whole-body staging includes pulmonary MDCT in all high-grade sarcomas; entity-dependent modifications and specific algorithms are recommended for sarcomas and non-malignant soft tissue tumors.Clinical relevance statementThese updated ESSR soft tissue tumor imaging guidelines aim to provide support in decision-making, helping to avoid common pitfalls, by providing general and entity-specific algorithms, techniques, and reporting recommendations for whole-body staging in sarcoma and non-malignant soft tissue tumors.Key PointsAn early, accurate, diagnosis is crucial for the prognosis of patients with soft tissue tumors.These updated guidelines provide best practice expert consensus for standardized imaging algorithms, techniques, and reporting.Standardization can improve the comparability examinations and provide databases for large data analysis.

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