Browsing by Author "Özçakir H.T."

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    Migration of an intrauterine contraceptive device to the sigmoid colon: A case report
    (Parthenon Publishing Group Ltd, 2003) Inceboz Ü.S.; Özçakir H.T.; Uyar Y.; Çaǧlar H.
    Background: Copper T intrauterine devices (IUDs) remain the mainstay of family planning measures in developing countries, but have been associated with serious complications such as bleeding, perforation and migration to adjacent organs or omentum. Although perforation of the uterus by an IUD is not uncommon, migration to the sigmoid colon is extremely rare. Here, we report a case of migration of an IUD to the sigmoid colon. Case report: A 40-year-old woman who had an IUD (Copper T), inserted 1 month after delivery, presented, 7 months later, with secondary amenorrhea and transient pelvic cramps. Clinical findings and ultrasonographic examinations of the patient revealed an 8-week pregnancy, while laboratory tests were normal. Transvaginal ultrasonography also visualized the IUD located outside the uterus, near the sigmoid colon, as if it were attached to the bowel. The pregnancy was terminated at the patient's wish; a diagnostic laparoscopy was performed concomitantly, which showed bowel perforation owing to the migration of the IUD. The device, which was partially embedded in the sigmoid colon, was removed via laparoscopy; however, because of bowel perforation, laparotomy was performed to open colostomy. Conclusion: This case report highlights the continuing need for intra- and postinsertion vigilance, since even recent advances in IUD technique and technology do not guarantee risk-free insertion.
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    Premature luteinization defined as progesterone estradiol ratio >1 on hCG administration day seems to adversely affect clinical outcome in long gonadotropin-releasing hormone agonist cycles
    (2004) Özçakir H.T.; Levi R.; Tavmergen E.; Göker E.N.T.
    Aim: To examine the effect of premature luteinization on the outcomes in long gonadotropin-releasing hormone agonist cycles. Methods: Two-hundred and forty-eight patients who had undergone assisted reproductive technology for infertility treatment between 2001 and 2002 were enrolled into the study. The patients were separated into two groups according to P/E2 ratios on human chorionic gonadotropin administration day. Group A consisted of the patients whose P/E2 ratio was 1 (n = 116) and Group B consisted of the patients with premature luteinization of which P/E2 ratio was > 1 (n = 132). The P/E2 ratio calculation was performed as follows: P (in ng/mL) × †1,000/E2 (in pg/mL). The primary outcome measures included oocyte quality, fertilization rates and clinical pregnancy rates. Results: The mean number of mature oocytes retrieved in the groups were 9.5 ± 4.8 and 6.4 ± 3.6, respectively, and the difference was statistically significant (P < 0.05). Although the difference between the fertilization rates in Group A and Group B was not statistically significant (P > 0.05), the clinical pregnancy rates seemed to be affected adversely in the Group B patients with premature luteinization (41.4% versus 28%, respectively; P < 0.05). Conclusion: Premature luteinization, defined as P/E2 > 1 on human chorionic gonadotropin administration day, in long gonadotropin-releasing hormone agonist cycles seems to adversely affect clinical outcome.
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    The relationship of pregnancy complications and AFP, HCG and estriol level detected in maternal serum; [Maternal kanda AFP, HCG ve ankonjuge östriol düzeylerinin gebelik komplikasyonlari i̇le i̇lişkisi]
    (2004) Bülbül Baytur Y.; Ulman C.; Laçin S.; Özçakir H.T.; Taneli F.; Çelik T.; Uyar Y.
    OBJECTIVE: The aim of the study was to determine the relationship of intrauterine death, prematurity, intrauterine growth retardation, surmaturation and preeclampsia with high and low AFP. high HCG and low estriol levels detected in maternal serum. STUDY DESING: 1020 patients who had undergone tripple test during pregnancy for intrauterine death, prematurity, surmaturation, intrauterine growth retardation and preeclampsia rates between 1999-2003 at Celal Bayar University Hospital were determined. The patients with high AFP levels (>2 MoM), high HCG levels (>2 MoM), low AFP levels (<0.5 MoM) and low estriol levels (<0.5 MoM) were compared to those with normal levels. The relationship of pregnancy complications and our findings examined. Statistical analysis were done with student t test and Chi square test by using SPSS for Windows version 10.0. RESULTS: Among 428 patients of whose files were useful for inclusion criteria, 30 of 31 patients of whom tripple test results were over the critical limit; 1/270 had undergone amniosynthesis. 4 of those 30 had Down syndrome. No other Down syndrome detected in other 26 patients who had a risky tripple test result neither with amniosynthesis nor in delivery. There were 14 patients with high AFP (>2 MoM). 55 patients with high HCG (>2 MoM), 13 patients with low AFP (<0.5 MoM) and 8 patients with low estriol levels (<0.5 MoM) among the patients those included to the study group. Those patients compared to the others with normal findings which consisted of 317 pregnants. There was statistically significant difference between low estriol levels and prematurity (p<0.05), however, there was no difference between high or low AFP levels and pregnancy complications. High HCG was significantly related with preeclampsia (p<0.05). CONCLUSION: Preeclampsia develoment with high HCG levels and the relation between low estriol and prematurity indicate that the patients with abnormal findings of tripple test are under the risk of obstetric complications. These patients should be consulted carefully for obstetric complications in addition to detection of cromozomal abnormality and malformation.