Browsing by Author "Özcan A."

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    The serum zinc and copper values of the morkaraman and tuj sheep grown up in the pasture conditions in and around kars
    (1998) Kaya N.; Utlu N.; Uyanik B.S.; Özcan A.
    This study was performed on 100 sheep, of which 50 were Morkaraman and 50 were Tuj, grown up in the pasture conditions in and around Kars. The serum zinc and copper values of the animals were analysed with Atomic Absorbtion Spectrophotometre. The serum zinc and copper values were respectively determined as; 40.56 ± 5.6 ug/dl, 80.10 ± 7.49 ug/dl in Morkaramans and, 38.72 ± 5.32 ug/dl. 75.04 ± 6.58 ug/dl in Tujs. There were no significant differences between the value of zinc and copper statistically.
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    A geotraverse across northwestern Turkey: Tectonic units of the Central Sakarya region and their tectonic evolution
    (2000) Göncüoǧlu M.C.; Turhan N.; Şentürk K.; Özcan A.; Uysal S.; Yaliniz M.K.
    In the Central Sakarya area of Turkey there are two main Alpine continental units, separated by a south verging ophiolitic complex which represents the root zone of the Izmir-Ankara Suture Belt. The Central Sakarya Terrane in the north includes two 'Variscan' tectonic units in its basement. The Sogut Metamorphic rocks represent a Variscan ensimatic arc complex and the Tepekoy Metamorphic rocks are characteristically a forearc-trench complex. The unconformably overlying Triassic Sogukkuyu Metamorphic rocks correspond to a part of the Karakaya Formation and are interpreted as a Triassic rift basin assemblage. These units are unconformably overlain by a transgressive sequence of Liassic-Late Cretaceous age that represents the northeastward deepening carbonate platform of the Sakarya Composite Terrane. The middle tectonic unit (the Central Sakarya Ophiolitic Complex) comprises blocks and slices of dismembered ophiolites, blueschists and basic volcanic rocks with uppermost Jurassic-Lower Cretaceous radiolarite-limestone interlayers. Geochemical data from basalt blocks suggest mid-ocean ridge basalt (MORB)- and suprasubduction-type tectonic settings within the Neotethyan Izmir-Ankara Ocean. The southern tectonic unit includes basal polyphase metamorphosed clastic rocks (Somdiken Metamorphics), intruded by felsic and basic dykes and overlain by thickbedded marbles. This assemblage is unconformably overlain by continental clastic rocks gradually giving way to thick-bedded recrystallized limestones, cherty limestones and pelagic limestones intercalated with radiolarites, and finally by a thick high pressure-low temperature (HP-LT) metamorphic synorogenic flysch sequence. This succession is identical to the passive continental margin sequences of the Tauride Platform. It is suggested that this passive margin was subducted during the Late Cretaceous in an intra-oceanic subduction zone and affected by HP-LT metamorphism. The emplacement of the allochthonous oceanic assemblages and the collision with the Central Sakarya Terrane was complete by the end of the Cretaceous.
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    Patient and physician delay in the diagnosis and treatment of non-small cell lung cancer in Turkey
    (Elsevier Ltd, 2015) Yurdakul A.S.; Kocatürk C.; Bayiz H.; Gürsoy S.; Bircan A.; Özcan A.; Akkoçlu A.; Uluorman F.; Çelik P.; Köksal D.; Ulubaş B.; Sercan E.; Özbudak T.; Göksel T.; Önalan T.; Yamansavci E.; Türk F.; Yuncu G.; Çopuraslan T.; Mardal T.; Tuncay E.; Karamustafaoğlu A.; Yildiz P.; Seçik F.; Kaplan M.; Çağlar E.; Ortaköylü M.; Önal M.; Turna A.; Hekimoğlu E.; Dalar L.; Altin S.; Gülhan M.; Akpinar E.; Savas T.; Firat N.; Çamsari G.; Özkan G.; Çetinkaya E.; Kamiloğlu E.; Çelik B.; havlucu Y.
    Aim: The early diagnosis and treatment of lung cancer are important for the prognosis of patients with lung cancer. This study was undertaken to investigate patient and doctor delays in the diagnosis and treatment of NSCLC and the factors affecting these delays. Materials and methods: A total of 1016 patients, including 926 (91.1%) males and 90 (8.9%) females with a mean age of 61.5. ±. 10.1 years, were enrolled prospectively in this study between May 2010 and May 2011 from 17 sites in various Turkish provinces. Results: The patient delay was found to be 49.9. ±. 96.9 days, doctor delay was found to be 87.7. ±. 99.6 days, and total delay was found to be 131.3. ±. 135.2 days. The referral delay was found to be 61.6. ±. 127.2 days, diagnostic delay was found to be 20.4. ±. 44.5 days, and treatment delay was found to be 24.4. ±. 54.9 days. When the major factors responsible for these delays were examined, patient delay was found to be more frequent in workers, while referral delay was found to be more frequent in patients living in villages (. p<. 0.05). We determined that referral delay, doctor delay, and total delay increased as the number of doctors who were consulted by patients increased (. p<. 0.05). Additionally, we determined that diagnostic and treatment delays were more frequent at the early tumour stages in NSCLC patients (. p<. 0.05). Discussion: The extended length of patient delay underscores the necessity of educating people about lung cancer. To decrease doctor delay, education is a crucial first step. Additionally, to further reduce the diagnostic and treatment delays of chest specialists, multidisciplinary management and algorithms must be used regularly. © 2015 Elsevier Ltd.
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    Clinical, Demographic, and Radiological Characteristics of Patients Demonstrating Antibodies Against Myelin Oligodendrocyte Glycoprotein
    (Galenos Publishing House, 2024) Koç S.; Şen S.; Terzi Y.; Kızılay F.; Demir S.; Aksoy D.B.; Kurtuluş F.; Bilge N.; Idilman E.; Uzunköprü C.; Güngör S.; Çilingir V.; Ethemoğlu Ö.; Boz C.; Gümüş H.; Kılıç A.K.; Kısabay A.; Bir L.S.; Turan Ö.F.; Soysal A.; Köseoğlu M.; Uzuner G.T.; Bayındır H.; Kabay S.C.; Çam M.; Yayla V.; Tan H.; Özcan A.; Taşkapıoğlu Ö.; Korkmaz M.; Tamam Y.; İnanç Y.; Efendi H.; Kotan D.; Yetkin M.F.; Bilgiç A.B.; Saçmacı H.; Demirci S.; Çelik Y.; Poyraz T.; Terzi M.
    Background: Optic neuritis, myelitis, and neuromyelitis optica spectrum disorder (NMOSD) have been associated with antibodies against myelin oligodendrocyte glycoprotein-immunoglobulin G (anti-MOG-IgG). Furthermore, patients with radiological and demographic features atypical for multiple sclerosis (MS) with optic neuritis and myelitis also demonstrate antibodies against aquaporin-4 and anti-MOG-IgG. However, data on the diagnosis, treatment, follow-up, and prognosis in patients with anti-MOG-IgG are limited. Aims: To evaluate the clinical, radiological, and demographic characteristics of patients with anti-MOG-IgG. Study Design: Multicenter, retrospective, observational study. Methods: Patients with blood samples demonstrating anti-MOG-IgG that had been evaluated at the Neuroimmunology laboratory at Ondokuz Mayıs University’s Faculty of Medicine were included in the study. Results: Of the 104 patients with anti-MOG-IgG, 56.7% were women and 43.3% were men. Approximately 2.4% of the patients were diagnosed with MS, 15.8% with acute disseminated encephalomyelitis (ADEM), 39.4% with NMOSD, 31.3% with isolated optic neuritis, and 11.1% with isolated myelitis. Approximately 53.1% of patients with spinal involvement at clinical onset demonstrated a clinical course of NMOSD. Thereafter, 8.8% of these patients demonstrated a clinical course similar to MS and ADEM, and 28.1% demonstrated a clinical course of isolated myelitis. The response to acute attack treatment was lower and the disability was higher in patients aged > 40 years than patients aged < 40 years at clinical onset. Oligoclonal band was detected in 15.5% of the patients. Conclusion: For patients with NMOSD and without anti-NMO antibodies, the diagnosis is supported by the presence of anti-MOG-IgG. Furthermore, advanced age at clinical onset, Expanded Disability Status Scale (EDSS) score at clinical onset, spinal cord involvement, and number of attacks may be negative prognostic factors in patients with anti-MOG-IgG. © Author(s).