Browsing by Author "Özcan O."

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    A new weight-bearing meniscal test and a comparison with McMurray's test and joint line tenderness
    (W.B. Saunders, 2004) Akseki D.; Özcan O.; Boya H.; Pinar H.
    Purpose: The purpose of this study was to describe a new weight-bearing McMurray's test (Ege's test) and to compare its diagnostic value with McMurray's test and joint line tenderness (JLT). We also aimed to determine if associated lesions had any effect on the diagnostic values of the 3 tests. Type of Study: Prospective controlled trial, clinical study. Methods: The study group consisted of 150 consecutive patients who had had symptoms related to intra-articular knee pathology, and arthroscopic diagnoses were used as the gold standard. Results: There were a total of 211 diagnoses on arthroscopy. A meniscus tear was found in 127 of the 150 patients; 90 had medial, 28 had lateral, and 9 had tears of both menisci. There were no statistically significant differences between the 3 tests in detecting a meniscal tear (P >. 05). However, better accuracy, sensitivity, and specificity rates were obtained with Ege's test for medial meniscal lesions (71%, 67%, and 81%, respectively). JLT also gave superior accuracy rates (71%), but the specificity of Ege's test was apparently higher than JLT (81% v 44%). The highest positive predictive value was also obtained with Ege's test (86%), whereas a superior negative predictive value was obtained with JLT (67%) in medial meniscal tears. Lateral meniscal tears were diagnosed more accurately than medial meniscal tears, and Ege's test gave results superior to the others (84%, 64%, 90% for accuracy, sensitivity, and specificity, respectively). Higher positive predictive values were obtained with McMurray's and Ege's tests than with JLT, but similar negative predictive values were achieved in all. A torn anterior cruciate ligament did not decrease the diagnostic values of the 3 tests, whereas the number of associated lesions in the knee negatively affected the diagnostic capabilities of the tests. Conclusions: Accuracies of traditional clinical meniscus tests may be improved by including Ege's test in the clinical examination. Level of Evidence: Level II, diagnostic.
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    First Report and in Silico Analysis of Leishmania virus (LRV2) identified in an autochthonous Leishmania major isolate in Turkey
    (Luigi Ponzio e figlio Editori, 2019) Kurt Ö.; Mansur N.; Çavuş I.; Özcan O.; Burak Batir M.; Gündüz C.; Sezerman U.; Özbilgın A.
    Leishmania virus (LRV) has previously been identified in different Leishmania species. Host-LRV interaction is associated with exacerbated clinical manifestations of cutaneous leishmaniasis (CL) and may cause poor therapeutic response. CL cases due to L. major with large skin lesions resistant to routine therapy were recently identified in Turkey. Here, we report the first autochthonous case of cutaneous leishmaniasis caused by LRV-positive Leishmania major, using conventional PCR targeting the viral capsid protein of LRV. The lesion of the case was 6 months old, relatively large (4 cm), and did not recover despite three consecutive intralesional applications of glucantime. Assessment of LRV’s influence on prognosis and clinical outcomes of leishmaniasis, based on additional studies, is required. ©2019 by EDIMES - Edizioni Internazionali Srl. All rights reserved