Browsing by Author "Özdemir, A"

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    CYTOGENETIC EFFECTS OF 48TITANIUM (48TI) ON MERISTEMATIC CELLS OF ROOT TIPS OF LENS CULINARIS MED.
    Sepet, H; Çanli, M; Özdemir, A; Bozdag, B; Özdemir, C
    Cytogenetic effects of (48)Titanium (Ti-48) on meristematic cells of root tips belonging to the plant (Lens culinaris Medik.) have been Investigated. Seeds of the plant, prepared were kept in Ti-48 standart for different time period as control during 1/4, 1/2, 1, 2, 4, 8, 12, 16, 20, 24 hours. Seeds treated with Ti-48 were made sprout and the root tips obtained were prepared for microscopic examination. At the end of the microscopic examinations, some abnormalities as chromosome breakings, chromosome dispersion, bridge chromosome, chromosome adherence, ring chromosome were observed. Abnormalities were seen at each treatment depended on the time periods. Variety and number of abnormality were usually seen to be increasing, depending on the increase of treatment time. The results obtained were evaluated statistically.
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    Elliptic motion on dual hyperbolic unit sphere (H)over-tilde02
    Kazaz, M; Özdemir, A; Ugurlu, HH
    Planar and spherical elliptic motions had been introduced by Karger and Novak [A. Karger, J. Novak, Space Kinematics and Lie Groups, Gordon and Breach Science Publishers, New York, London, 1985]. Also, a dual spherical elliptic motion has been defined by Yapar [Z. Yapar, Spatial conchoidal and elliptic motions, Mechanism and Machine Theory 27 ( 1) ( 1992) 75-91]. In this paper, we de. ne the elliptic motion on a dual hyperbolic unit sphere e (H) over tilde (2)(0) in the dual Lorentzian space D-1(3) with dual signature (+, +, -) and carry the results to the Lorentzian line space IR13 by means of Study's mapping. (C) 2008 Elsevier Ltd. All rights reserved.
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    STATISTICAL COMPARISON ON NUMERICAL ANATOMICAL VALUES OF CROCUS L. TAXA
    Özdemir, A; Akyol, Y
    This study aims to statistically compare the numerical values of root and scape anatomy of 13 Crocus taxa. Anatomical variations in 13 Crocus L. taxa have been investigated by means of numerical methods (Analysis of variance and Pearson correlation). By the analysis of the investigated taxa from ten anatomy related characters, it has been determined that endodermis width, pericycle length and trache cell diameter are the best character pairs which represent the variations in them. It has been also found that the results from numerical analysis of the anatomy characters can provide additional anatomical evidences for recognition of the taxa.
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    AN ANATOMICAL STUDY OF Scilla (SCILLOIDEAE) SECTION Chionodoxa AND Scilla bifolia IN TURKEY
    Yildirim, H; Yetisen, K; Özdemir, A; Özdemir, C
    In the present study Scilla luciliae, S. forbesii, S. sardensis, S. siehei, Scilla x allenii and S. bifolia are compared anatomically. Some differences have been found in root, scape, and leaf anatomy of the taxa, and commented. S. luciliae, S. forbesii, S. sardensis and S. siehei have a metaxylem at the center of the root, others have 3-4 number metaxylem. Vascular bundles in two row in S. luciliae and S. forbesii in a single row in S. sardensis, Scilla x allenii and S. bifolia though in three rows in S. siehei. Aerenchyma tissue is present in mesophyll of five taxa leaf except S. sardensis. The anatomical variations in the taxa have been investigated by means of numerical methods (Analysis of variance and Pearson correlation). By the analysis of the investigated taxa from 12 anatomy related characters, it has been also found that the results from numerical analysis of anatomy characters can provide additional evidences, which correspond to the anatomy for the recognition of the taxa.
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    STATISTICAL COMPARATIVE PETIOL ANATOMY OF Salvia SP.
    Özdemir, A; Özdemir, AY; Yetisen, K
    In this study, petiol anatomy of 17 Salvia sp. taxa were compared statistically. In all the studied taxa, some differences were found in the petiole shape, number of vascular bundles and the presence of chlorenchyma. Anatomical variations in 17 Salvia taxa have been investigated by means of numerical methods (Analysis of variance and Pearson correlation). By the analysis of the investigated taxa from 17 leaf anatomy related characters, it has been determined that epidermis width and trachea diameter are the best character pairs which represent the variations in them. It has been also found that the results from numerical analysis of the leaf anatomy characters can provide additional evidences that correspond to the anatomy for the recognition of the taxa.
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    Evaluation of antidepressant-like effect of 2-pyrazoline derivatives
    Gok, S; Demet, MM; Özdemir, A; Turan-Zitouni, G
    Many studies have shown that pyrazoline derivatives have therapeutic potential as antidepressant drugs. In this study, we aimed to investigate the antidepressant-like effect of eight new 1-[(N,N-disubstituted thiocarbamoylthio)acetyl]-3-(2-thienyl)-5-aryl-2-pyrazolines that have previously been synthesized in our laboratory. Antidepressant-like activity was investigated in mouse forced swimming test (FST). Drug-induced effects on motor function were also tested by using digitized motor activity monitoring system. Shortened immobility time in FST was accepted as indicator of antidepressant-like activity. Results showed that three of eight pyrazoline compounds (1b, 1d, 1g) significantly shortened immobility time compared with control. Compound 1b was found to be more effective in FST than were clomipramine and tranylcypromine, used as reference antidepressant drugs. This compound also significantly increased horizontal motor activity, like clomipramine, compared with control mice. These results suggest that the N,N-disubstituted dithiocarbamate moiety of pyrazoline derivatives may have therapeutic antidepressant potential.
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    PLL Based Digital Adaptive Filter for Detecting Interharmonics
    Özdemir, A; Tastan, A
    Studies on the PLL (phase locked loop) based interharmonic measurements have been considerably increased recently. The method proposed in this study is a hybrid method based on the frequency analysis. The proposed method presents solutions for the leading problems about the interharmonic measurement, such as fundamental frequency shifting, spectral leakage, and picketfence effect, using digital PLL and adaptive notch filter. In addition, a new approach is presented to solve the multizero crossing problem encountered in the analysis of the harmonicinterharmonic. Both simulative and field data tests have been performed to verify the effectiveness of the proposed method.
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    A STATISTICAL COMPARISON OF ANATOMICAL FEATURES IN SOME Ornithogalum SP SPECIES
    Özdemir, A; Kocayigit, H; Yetisen, K; Akyol, Y; Özdemir, C
    In the present study, Ornithogalum narbonense, O. montanum, O. wiedemannii, O. sigmoideum and O. lanceolatum species were compared statistically with respect to anatomical characters. Some differences were found in root, stem and leaf anatomy of the species. These differences and similarities were indicated in this study. A big metaxylem was present in all root cross sections, except for O. lanceolatum, which has three metaxylema. 2-3 layered annular type collenchyma were present in all species. Aerenchyma is present in all mesophiles.
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    Determination of Major and Minor Elements in the Malva sylvestris L. from Turkey Using ICP-OES Techniques
    Hicsönmez, Ü; Erees, FS; Özdemir, C; Özdemir, A; Çam, S
    In this work, Malva sylvestris var. mauritiana (L.) leaves were collected from different points in Muradiye region of Manisa-Turkey. The leaves were dissolved by wet digestion method using a mixture of mineral acid. Concentrations of Ag, Al, B, Ba, Bi, Ca, Cd, Co, Cr, Cu, Fe, K, La, Mg, Mn, Na, Ni, Pb, Sn, Sr, Sb, Si, Ti, U, Zn, and Zr in prepared solutions were determined by using inductively coupled plasma optical emission spectrometry (ICP-OES). High Ca (13,848 mg/kg) and Mg (1,936 mg/kg) concentrations were found at the leaves. Obtained values were compared with the internationally permitted (standard) values. The results of elements were analyzed statistically (analysis of variance test). For different leaf sizes, concentration factors were calculated.
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    Cytogenetic effects of C6H4(CH3)2 (xylene) on meristematic cells of root tips of Vicia faba L. and mathematical analysis
    Alaca, C; Özdemir, A; Bozdag, B; Özdemir, C
    Xylene is a readily flammable and poisonous liquid with a chemical formula of C6H4(CH3)(2). It is used as raw material or auxiliary raw material in many industrial products such as dye, pencil, agricultural chemicals, rubber, fiber, glue and diaper. In this study, cytogenetic effects of xylene, on the meristematic cells of root tips of V. faba L. used as food have been investigated. For this purpose, the seeds of the plant have been treated with xylene solutions prepared in different concentrations for different time periods. Chromosomes at the root tips have been looked and the effect of xylene has been determined. The abnormalities as chromosome breaking, chromosome dispersion, bridge chromosome, chromosome adherence, ring chromosome have been observed. Abnormalities have been seen at each treatment depended on the time periods. In addition to these visible damages of xylene in the study, possible damages on chromosomes carrying genetic codes of living beings to future generations have been investigated and mathematical analyzes has been made. The results obtained have been evaluated statistically.
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    NUMERICAL COMPARATIVE HAIRS OF SOME LAMIACEAE TAXA COLLECTED FROM TURKEY
    Özdemir, A; Kocabas, O
    In this study, glandular and aglandular hairs were examined and compared numerically in the vegatative and reproductive organs of Salvia viridis, Salvia verticillata subsp. amasiaca, Salvia virgata, Phlomis pungens var. pungen, Phlomis pungens var. hispida, Stachys cretica subsp. anatolica, Stachys cretica subsp. smyrnaea, Teucrium scordium subsp. scordioides. It has been observed that all taxa which are collected Western and Northern Anatolia have glandular hairs and aglandular hairs of various shapes, size and modes of secretion. The hairs variations in eight Lamiaceae taxa were been investigated by means of numerical methods (Analysis of variance and Pearson correlation). It was also found that the results from numerical analysis of the hairs characters can provide additional evidences for the recognition of the taxa.
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    Analysis of Strengthened Composite Beams Under Flexural Stress
    Ercan, E; Arisoy, B; Demir, A; Özdemir, A
    A steel-concrete composite beam is composed of a steel beam and concrete slap connected with shear connectors. Composite beams are highly efficient structural members in order to load carrying capacity because the tension component of the force pair originating from bending is carried by the steel profile and the compressive component is carried by the concrete slab in composite beams. In this study, numerical and experimental analysis of steel-concrete composite and strengthened steel-concrete composite beams is presented. In experimental study, one strengthened and one un-strengthened specimens are produced and tested in bending. Strengthening is produced applying carbon fiber reinforced polymers sheet to the lower flange of the steel beam and using steel fiber reinforced concrete in the concrete slab. Specimens are tested under four-point loading test. During the tests, load, deflection and strain values are collected by data acquisition system. In numerical study, the finite element models of the steel-concrete composite beams are generated and analyzed by Atena-GiD program. Comparison and evaluations are made in terms of strength, applicability, stiffness and energy consumption about the steel-concrete composite beams with carbon fiber reinforced polymers and steel fibered concrete for both numerical and experimental results.
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    Cytogenetic effects of 99technetium on meristematic cells of root tips of Vicia faba L. andstatistical comparison
    Özdemir, A; Bozdag, B; Sepet, H; Parlak, Y; Kocabas, O; Erees, FS; Özdemir, C
    In this study, cytogenetic effects of (99)technetium (Tc-99) on meristematic cells of root tips belonging to Vicia faba L. have been investigated. Seeds of the plant were prepared and kept in Tc-99 standard for different time periods: 1/12, 1/4, 1/2, 1, 2, 3, 4, 5, 6 and 12 h. Seeds treated with Tc-99 were sprouted and the root tips obtained were prepared for microscopic examination. Some abnormalities e.g. chromosome breaking, chromosome dispersion, bridge chromosomes, chromosome adherence and ring chromosomes were observed. Abnormalities seen for each treatment depended on the time period. The variety and number of abnormalities usually increased with increased treatment time. The results obtained were evaluated statistically.
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    Gender stereotypes and professional experiences of female nurses in Turkiye
    Aca, Z; Kircal-Sahin, A; Özdemir, A; Kaymakci, YS
    Introduction Gender roles and stereotypes play a significant role in shaping the nursing profession, perpetuating systemic inequities that negatively impact professional experiences and healthcare system efficiency. In Turkiye, patriarchal norms and systemic disparities exacerbate these workplace challenges, particularly for female nurses.Methods This qualitative study utilized semi-structured interviews with 13 female nurses working in intensive care units to examine the influence of societal expectations, workplace discrimination, and institutional policies on gender inequities in nursing.Results The findings reveal that cultural norms, family influence, and constrained career planning often channel women into nursing, reinforcing perceptions of the profession as an extension of caregiving roles. While participants rejected the notion of nursing as a women's profession, their narratives highlighted the pervasive impact of gendered expectations. Additionally, political favoritism and nepotism were identified as factors exacerbating workplace challenges, reflecting broader systemic issues in Turkiye's labor market. The normalization of gender norms and their internalization by female nurses further complicate efforts to combat discrimination.Discussion The study underscores the necessity for policy interventions to address systemic gender inequities in nursing. Recommendations include implementing mandatory gender equality education within healthcare institutions, stricter enforcement of anti-violence laws, and the establishment of psychological and legal support systems for workplace violence victims. Additional measures, such as childcare support and regulations against marital status-based discrimination, are essential to mitigate inequities. By addressing societal, cultural, and institutional factors, this research provides actionable strategies for healthcare organizations and policymakers to promote equity and improve sector efficiency.
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    RESPONSE OF CROCUS L. (IRIDACEAE) TO ECOLOGICAL CHARACTERISTICS
    Özdemir, A; Akyol, Y; Özdemir, AY; Özdeimir, C
    Three subspecies of Crocus specious (subsp. speciosus, subsp. ilgazensis, subsp. xantholaimos) two of them being endemics Blacksea region) were investigated for ecological characteristics. It has been observed that these subspecies usually prefer the soil which is acidic and has no salt in it. No statistical difference in per cent N and P was observed in all the three subspecies except in per cent K.
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    Comparison of refugee patients with cystic fibrosis and their counterpart children from Turkey during the war
    Yilmaz, AI; Pekcan, S; Eyüboglu, TS; Hangül, M; Arslan, H; Kilinç, AA; Çokugras, H; Arik, E; Keskin, Ö; Özdemir, A; Ersoy, M; Ersoy, A; Köse, M; Özsezen, B; Ünal, G; Ercan, Ö; Girit, S; Oksay, SC; Gökdemir, Y; Karadag, B; Sen, V; Çakir, E; Yüksel, H; Tekin, MN; Aslan, AT
    Since the outbreak of the Syrian civil war in 2011, the population of Arab refugees in Turkey has rapidly increased. While cystic fibrosis (CF) is believed to be rare among Arabs, recent studies suggest it is underdiagnosed. This study aims to present the demographic, clinical, and genetic characteristics of CF patients among Arab refugees in Turkey. Additionally, a comparison is made between the findings in the National CF Registry 2021 in Turkey (NCFRT) and the refugee CF patient group. The study included refugee patients between the ages of 0 and 18 years who were diagnosed with CF and received ongoing care at pediatric pulmonology centers from March 2011 to March 2021. The study examined demographic information, age at diagnosis, age of diagnosis of patients through CF newborn screening (NBS), presenting symptoms, CF transmembrane conductance regulator (CFTR) mutation test results, sputum culture results, weight, height, and body mass index (BMI) z score. Their results were compared with the NCFRT results. The study included 14 pediatric pulmonology centers and 87 patients, consisting of 46 (52.9%) boys and 41 (47.1%) girls. All of the patients were Arab refugees, with 80 (92%) being Syrian. All the patients were diagnosed in Turkey. The median age at diagnosis of patients was 22.33 (interquartile range, 1-258) months. The median age of diagnosis of patients through NBS was 4.2 (interquartile range, 1-12) months. The median age of older patients, who were unable to be included in the NBS program, was 32.3 (interquartile range, 3-258) months. Parental consanguinity was observed in 52 (59.7%) patients. The mutation that was most frequently found was F508del, which accounted for 22.2% of the cases. It was present in 20 patients, constituting 32 out of the total 144 alleles. There was a large number of genetic variations. CFTR genotyping could not be conducted for 12 patients. These patients had high sweat tests, and their genetic mutations could not be determined due to a lack of data. Compared to NCFRT, refugee patients were diagnosed later, and long-term follow-up of refugee CF patients had significantly worse nutritional status and pseudomonas colonization. Conclusion: Although refugee CF patients have equal access to NBS programs and CF medications as well as Turkish patients, the median age at diagnosis of patients, the median age of diagnosis of patients through NBS, their nutritional status, and Pseudomonas colonization were significantly worse than Turkish patients, which may be related to the difficulties of living in another country and poor living conditions. The high genetic heterogeneity and rare mutations detected in the refugee patient group compared to Turkish patients. Well-programmed NBS programs, thorough genetic studies, and the enhancement of living conditions for refugee patients in the countries they relocate to can have several advantages such as early detection and improved prognosis.What is Known:center dot Children who have chronic diseases are the group that is most affected by wars.center dot The outcome gets better with early diagnosis and treatment in patients with Cystic Fibrosis (CF).What is New:center dot Through the implementation of a newborn screening program, which has never been done in Syria previously, refugee patients, the majority of whom are Syrians were diagnosed with cystic fibrosis within a duration of 4 months. center dot Despite equal access to the newborn screening program and CF medications for both Turkish patients and refugee patients, the challenges of living in a foreign country have an impact on refugees.
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    Effects of shear stresses and rotary inertia on the stability and vibration of sandwich cylindrical shells with FGM core surrounded by elastic medium
    Sofiyev, AH; Hui, D; Valiyev, AA; Kadioglu, F; Turkaslan, S; Yuan, GQ; Kalpakci, V; Özdemir, A
    The vibration and stability of axially loaded sandwich cylindrical shells with the functionally graded (FG) core with and without shear stresses and rotary inertia resting Pasternak foundation are investigated. The dynamic stability is derived based on the first order shear deformation theory (FSDT) including shear stresses. The axial load and dimensionless fundamental frequency for FG sandwich shell with shear stresses and rotary inertia and resting on the Pasternak foundation. Finally, the influences of variations of FG core, elastic foundations, shear stresses and rotary inertia on the fundamental frequencies and critical axial loads are investigated.
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    Comparison of Clinical Outcomes between Single- and Multiple-Perforator-Based Free Thoracodorsal Artery Perforator Flaps: Clinical Experience in 87 Patients
    Karaaltin, MV; Erdem, A; Kuvat, S; Çavdar, G; Kerem, H; Baghaki, S; Canter, HI; Özdemir, A
    Background: Although thoracodorsal artery perforator flaps have not gained popularity in the reconstructive era, the results of recent studies regarding the vascularity of thoracodorsal artery perforator flaps are promising. In the present study, the authors aimed to determine the clinical outcomes of free multiple-perforator versus single-perforator thoracodorsal artery perforator flaps. Methods: Eighty-seven patients with various defects underwent reconstruction with free thoracodorsal artery perforator flaps. The flap was used for upper extremity reconstruction in 43 patients (49.4 percent), for head and neck reconstruction in 16 patients (18.4 percent), and for lower extremity reconstruction in 28 patients (32.2 percent). Of the 87 flaps, 48 (55.2 percent) were based on a single perforator, whereas 39 flaps (44.8 percent) were based on multiple perforators. The single-and multiple-perforator-based thoracodorsal artery perforator flaps were compared regarding clinical outcomes and morbidity. Results: The morbidity rate was found to be significantly higher in the single-perforator-based group. Of the patients in the single-perforator group, seven patients had transient venous congestion, five were heparinized and treated with leeches for permanent venous congestion, six had partial necrosis, and one had total necrosis. In the multiple-perforator-based group, two patients had transient venous congestion, and no partial or total necrosis was observed. Conclusion: Despite the fact that dominant perforators may often be absent, this study showed that a multiple-perforator-based thoracodorsal artery perforator flap may be more reliable with safe vascularity compared with a single-perforator-based flap. (Plast. Reconstr. Surg. 128: 158e, 2011.)
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    Evaluation of factors affecting bone mineral density in CF patients through CF registry of Turkey
    Soydas, SSA; Tugcu, GD; Gençoglu, MY; Cinel, G; Emiralioglu, N; Yalçin, E; Kiper, N; Sen,; Altintas, DU; Çokugras, H; Kilinç, AA; Yazan, H; Ünal, G; Yilmaz, A; Çaglar, HT; Damadoglu, E; Irmak, I; Demir, E; Öztürk, GK; Bingöl, A; Basaran, E; Sapan, N; Aslan, AT; Asfuroglu, P; Harmanci, K; Köse, M; Hangül, M; Özdemir, A; Özcan, G; Gayretli, ZG; Keskin, Ö; Yüksel, H; Özdogan, S; Topal, E; Çaltepe, G; Can, D; Ekren, PK; Kiliç, M; Eyüboglu, TS; Pekcan, S; Çobanoglu, N; Çakir, E; Özçelik, U; Dogru, D
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    Patients with cystic fibrosis who could not receive the CFTR modulator treatment: What did they lose in 1 year?
    Uytun, S; Cinel, G; Polat, SE; Tabakçi, SO; Kiper, N; Yalçin, E; Tural, DA; Özsezen, B; Sen, V; Sen, HS; Altintas, DU; Çokugras, H; Kilinç, AA; Baskan, AK; Yazan, H; Çollak, A; Uzuner, S; Ünal, G; Yilmaz, AI; Çaglar, HT; Damadoglu, E; Irmak, I; Demir, E; Öztürk, GK; Bingöl, A; Basaran, E; Sapan, N; Canitez, Y; Aslan, AT; Asfuroglu, P; Harmanci, K; Köse, M; Hangül, M; Özdemir, A; Çobanoglu, N; Özcan, G; Keskin, Ö; Yüksel, H; Özdogan, S; Topal, E; Çaltepe, G; Can, D; Ekren, PK; Kiliç, M; Emiralioglu, N; Eyüboglu, TS; Pekcan, S; Çakir, E; Özçelik, U; Dogru, D
    BackgroundCystic fibrosis (CF) is an autosomal recessive disorder caused by CF transmembrane conductance regulator (CFTR) genetic variants. CFTR modulators improve pulmonary function and reduce respiratory infections in CF. This study investigated the clinical and laboratory follow-up parameters over 1 year in patients with CF who could not receive this treatment. MethodsThis retrospective cohort study included 2018 and 2019 CF patient data from the CF registry of Turkey. Demographic and clinical characteristics of 294 patients were assessed, who had modulator treatment indications in 2018 but could not reach the treatment. ResultsIn 2019, patients younger than 18 years had significantly lower BMI z-scores than in 2018. During the 1-year follow-up, forced expiratory volumes (FEV1) and FEV1 z-scores a trend toward a decrease. In 2019, chronic Staphylococcus aureus colonization, inhaled antipseudomonal antibiotic use for more than 3 months, oral nutritional supplement requirements, and oxygen support need increased. ConclusionsPatients who had indications for modulator treatments but were unable to obtain them worsened even after a year of follow-up. This study emphasized the importance of using modulator treatments for patients with CF in our country, as well as in many countries worldwide.