Browsing by Author "Üçer O."
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Item The relationship between smoking and lower urinary tract symptoms: Community based study; [Si̇gara alişkanliǧi i̇le alt üri̇ner si̇stem yakinmalari arasindaki̇i̇li̇şki̇: Topluma dayali çalişma](2007) Temeltaş G.; Müezzinoǧlu T.; Üçer O.; Lekili M.; Büyüksu C.Introduction: The studies, investigated the relationship between smoking and benign prostatic hyperplasia (BPH), are commonly clinically based. We aimed that whether smoking has any effect on BPH and/or lower urinary tract symptoms in a community based fashion. Materials and Methods: The forms of international prostate symptom score (I-PSS), quality of life (QoL) and asking smoking addiction were fulfilled by 255 men over 40 years old living in a small town of Manisa. Meanwhile prostatic volume and post-voiding residual urine volume calculations with ultrasound were evaluated. Results: While the degree of smoking (package/year) increased, I-PSS, QoL and residual urine volume slightly increased, but no correlation found with Pearson co-efficient. Although no statistically significant relation was observed, prevalence of BPH in this population was higher in smoking men than non smoking men. Conclusion: In this study, although no statistically correlation was found between smoking and BPH, it is observed that smoking is slightly effect the prevalence of BPH. It may be speculated that smoking has variable effects on sex steroids.Item Influence of the erectile dysfunction on quality of life accompanying diabetes mellitus: A longitudinal, controlled study; [Şeker hastaliǧina eşlik eden erektil disfonksiyonun yasam kalitesi üzerine etkileri: Longitudinal kontrollü bir çalişma](2008) Okur M.; Gümüs B.; Üçer O.; Karatas T.C.; Özmen E.; Büyüksu C.Introduction: Erectile dysfunction (ED) is one of the most common complications of Diabetes Mellitus (DM) in males and has a negative impact on the quality of life (QoL). The number of studies related with this subject is limited in the literature. QoL was evaluated and compared in diabetic patients with and without ED. Materials and Methods: Patients with ED who applied to our outpatient clinics (Celal Bayar University, Medical Faculty, Department of Urology) were included in the study. We interviewed 82 patients with DM+ED, 85 patients with ED and 65 normal (control) male subjects. All men (study and control groups) were asked to fill the IIEF (International Index of Erectile Function), CES-D (Center of Epidemiological Studies-Depression), BAI (Beck Anxiety Inventory), PIED (Pyschological Impact of Erectile Dysfunction) forms. Sildenafil citrate was administered as a medical treatment. Same forms were asked to be filled again in the 3th, 6th, 9th months of the therapy. Results: We observed that QoL of the patients with DM+ED and ED were affected negatively. ED was worse in the DM group compared to others. Significant improvements were detected in both QoL and ED in 3th and 6th months of the therapy. Conclusion: Our data show that treatment of ED significantly improves QoL in the patients with DM therefore, presence of ED has to be assessed in the patients with DM.Item Sponge migration into the urinary bladder following inguinal hernia repair; [İngüinal herni onarιmι sonrasι mesaneye spanȩ migrasyonu](2008) Üçer O.; Şahin M.O.; Gümüş B.Introduction: Foreign bodies in the bladder might cause lower urinary tract symptoms which is usually easy to diagnose. However, we might sometimes meet unexpected findings. We present endoscopical removal of a bladder sponge from a patient who underwent bilateral inguinal hernia repair 7 years ago.Item Does late-onset hypogonadism occur by aging? The evaluation of IIEF, Ams-Q and biochemical parameters; [Yaşlanmayla geç başlayan hipogonadizm oluşuyor mu? IIEF, Ams-Q ve biyokimyasal deǧerlendirilmesi](Turkiye Klinikleri, 2010) Üçer O.; Gümüş B.; Okur M.; Karataş T.C.; Büyüksu C.Objective: The aim of this study is to investigate whether biochemical (hormonal) hypogonadism occurs by aging and whether AMS-Q (Aging Male Symptoms-Questionnaire) and IIEF (International Index of Erectile Function) forms are adequate in order to evaluate its presence in case it occurs. Material and Methods: A total of 182 males who applied to the outpatient clinics of Urology Department and whose ages were between 45-90 years were included in the study. Those who had diabetes mellitus, hypertension, coronary artery disease, dyslipidemia, any psychiatric disorder and any malignancy were excluded. The patients were classified into three groups (Group 1; 45-54, Group 2; 55-64 and Group 3; over 65 years). All participants were asked to complete IIEF and AMS-Q forms and serum levels of total testosterone, free testosterone, LH, DHEA-S, SHBG and prolactin were measured. Results: Total testosterone and prolactin levels did not change with aging. Although free testosterone, bio-available testosterone and DHEA-S levels decreased with age, it was detected that LH and SHBG levels were increased. While IIEF scores decreased with age, however AMS-Q scores did not change. When subgroups of AMS-Q were taken into consideration, sexual scores increased, and a decrease in somatic and psychological scores was detected. There was a strong relationship between IIEF-EF (erectile function) and AMS-Sexual forms. Conclusion: All of the data indicate that secondary hypogonadism occurs by aging and consequent symptoms (especially sexual ones) can be evaluated with IIEF and AMS-Sexual forms. © 2010 by Türkiye Klinikleri.Item Comparison of audiovisual sexual stimulation test with nocturnal penile tumescence test in the evaluation of erectile dysfunction by using RigiScan; [RigiScan ile erektil disfonksiyonun deǧerlendirilmesinde nokturnal penil tümesans testi ile vizüel seksüel stimülasyon testinin karşılaştırılması](AVES, 2010) Incirci M.; Üçer O.; Karataş T.C.; Ateşçi Y.Z.; Gümüş B.Objective: Nocturnal penile tumescence (NPT) test is a time-consuming, cumbersome, and relatively expensive method which is used for the diagnosis of erectile dysfunction (ED). The aims of the study were to clarify the relationship between erotic and nocturnal erections and to evaluate the diagnostic efficacy of the audiovisual sexual stimulation (AVSS) test with and without medication. Materials and methods: A total of 30 patients with ED were examined. Each patient filled in an International Index of Erectile Function-5 (IIEF-5) questionnaire. AVSS and NPT tests were performed using the RigiScan Plus. AVSS test was performed with and without medication (sildenafil citrate 50 mg). Patients were divided into two groups (psychogenic and organic groups) according to NPT and AVSS test results. Results: The mean age of the patients was 46.4 (23-69) years and IIEF-5 score was 10.8±4.5. Positive AVSS test was found in 18 (85.7%) of the 21 patients with positive NPT test. Negative AVSS test was found in 7 (77, 8%) of the 9 patients with negative NPT test. The specificity of AVSS test was 85.7% and sensitivity was 77.8% for the psychogenic groups. The overall accuracy rate was 83.3%. Conclusion: The NPT test is more expensive, cumbersome, and discomfortable than the AVSS test. Although efficiency of both tests is similar, the AVSS test seems more advantageous. We suggest that the AVSS test without medication should be performed as the first step in the diagnosis of the patients with ED. In patients with negative test result, the AVSS test with medication should be performed as the second step diagnostic method.Item The treatment of late-onset hypogonadism; [Geç başlayan hipogonadizmde tedavi](AVES, 2014) Üçer O.; Gümüş B.Late-onset hypogonadism (LOH) in aging men is a clinical and biochemical syndrome caused by an age-related decline in testosterone. Despite published in guidelines and recommendations, uncertainty surrounds the profile of clinical symptoms as well as the biochemical threshold of diagnosis. The only evidence-based treatment of late-onset hypogonadism is testosterone replacement therapy. The actual available evidence of the long-term risks and outcomes of testosterone-replacement therapy remains very limited, and carefully designed placebo-controlled trials of testosterone administration to assess the risks and benefits of such a therapy are required. Until such evidence is available, testosterone treatment should be restricted to elderly men with very low testosterone levels in the presence of clinical symptoms, and the advantages and disadvantages need to be accurately assessed. Careful monitoring of potential side effects is necessary. The purpose of this review is to discuss what is known and what remains unclear with respect to the benefits and risks of testosterone replacement treatment. © 2014 by Turkish Association of Urology.Item Quantifying subjective assessment of sleep quality, quality of life and depressed mood in children with enuresis(2014) Üçer O.; Gümüş B.Aim: The aim of this study was to compare a group of children who has monosymptomatic nocturnal enuresis (MNE) with a healthy control group by assessing their depression scales, quality of life and sleep quality. Methods: Hundred and one children with MNE and 38 healthy controls are included in the study, aged between 8 and 16 years old. All participants were performed the Pediatric Quality of Life Inventory (PedsQL 4.0), Depression Scale for Children (CES-DC) and The Pittsburgh Sleep Quality Index (PSQI) tests. The two groups were compared for their demographic factors and for the results of the tests above. Results: There were no significant differences between the two groups according to age, gender and other demographic factors. Quality of life, depression and sleep quality scores implied worse health in the patient group. The PedsQL scores were assessed as 1,659.90 ± 296.01 in the patient group and 1,818.42 ± 227.92 in the control group (p = 0.001). The CES-DC scores were 11.74 ± 6.11 in the patient group and 7.00 ± 3.97 in the control group (p < 0.001). And the PSQI scores were 2.58 ± 2.48 in the patient group, 1.15 ± 1.10 in the control group (p < 0.001). Also in the patient group, there was a positive correlation between participants' ages and the PedsQL (p = 0.010; r = 0.256), the CES-DC (p = 0.000; r = 0.382), the PSQI (p = 0.000; r = 0.403) scores. The success parameters at school were significantly worse in the patient group (p = 0.05). Conclusion: All our findings show us that the children with nocturnal enuresis were affected negatively because of their disease; especially when they grow up the scores get worse health, so we suggest that treatment must be started at suitable age according to guidelines. © 2013 The Author(s).Item Assessment of sexual function in women with macromastia and their partners(Ediciones Doyma, S.L., 2015) Üçer O.; Sir E.; Güngör M.; Keçeci Y.; Aksoy A.; Gümüş B.Objective: To investigate the sexual function in patients with macromastia and their partners. Materials and methods: 48 patients with macromastia and 30 healthy controls and their partners were enrolled in the study. The sexual function of the women and their partners was evaluated by using the Index of Female Sexual Function (IFSF) and International Index of Erectile Function (IIEF), respectively. Results: Mean ages of the patients and controls were respectively, 33.27 ± 5.24 and 32.06 ±. 3.91 (p > 0.05). Mean IFSF scores of the patients and controls were 23.21 ± 3.16 and 27.33 ± 4.94 (p = 0.00), respectively. All of the subscale scores of IFSF in the patient group were significantly lower than in the control group. Mean IIEF scores of the patients' and controls' partners were 60.33 ± 11.46 and 65.25 ± 6.18 (p = 0.04), respectively. Conclusion: In this study, Macromastia was shown to affect sexual function of women and their partners adversely. © 2014 Asociación Española de Andrología, Medicina Sexual y Reproductiva.Item Effect of reduction mammaplasty on sexual activity(Lippincott Williams and Wilkins, 2016) Sir E.; Üçer O.; Güngör M.; Aksoy A.; Keçeci Y.; Gümü B.Aim: This study aimed to evaluate the effects of reduction mammaplasty operation on sexual functions of the patients with macromastia and of their partners. Materials and Methods: Thirty-nine patients with macromastia and their partners were assessed for their sexual function before and 6 months after reduction mammaplasty. Sexual function of the women and their partners were evaluated using the Index of Female Sexual Function (IFSF) and the International Index of Erectile Function (IIEF), respectively. Controls (n = 33) were chosen from healthy hospital staff and their partners. Preoperative and postoperative scores were statistically compared with the controls' scores by using Student t test. Also, preoperative and postoperative scores were compared by using paired t test. Results: The mean of age and body mass index of the women and their partners in the patient and control group were similar (P = 0.07). Before the operation, the mean of IFSF scores in the patient and control group were 22.75 (3.45) and 27.28 (5.05), respectively (P < 0.001). After the operation, the mean of IFSF scores in the patient group increased significantly to 27.67 (P < 0.001). The postoperative scores of all IFSF subscales except lubrication subscale were higher than the preoperative scores. Although there was no significant difference between preoperative and postoperative IIEF-total scores, postoperative IIEF-erectile function and IIEF-intercourse satisfaction scores were significantly reduced (P < 0.05). Conclusions:We found that macromastia adversely affected female sexual function but reduction mammaplasty eliminated this adverse effect. We also found that the partners' erectile function and intercourse satisfaction reduced after the operation. This reduction may be due to psychological effects. © 2016 Wolters Kluwer Health, Inc. All rights reserved.Item Sexual function and hormone profile in young adult men with idiopathic gynecomastia: Comparison with healthy controls(IOS Press, 2016) Sir E.; Üçer O.; Aksoy A.; Güngör M.; Ceylan Y.Objectives: To compare sexual function and hormone profile in male patients with gynecomastia with matched controls. MATERIALS-METHODS: Forty-seven male subjects with gynecomastia and thirty healthy controls were enrolled in this study. Serum free T3, free T4, TSH, FSH, prolactin, estradiol, total testosterone, free testosterone, DHEA-SO4, LH and total PSA were measured in the patients and controls. Sexual function of the patients and controls were evaluated using International Index of Erectile Function (IIEF). The hormone values and IIEF scores of the patients were statistically compared with the controls'. RESULTS: The mean of age, body mass index, right and left testicular volume in the patient and control group were similar. The mean FSH and free T3 values of the patients were significantly lower than the controls (p = 0:007 and p = 0:03, respectively). The mean of the other hormone values in the both groups were found to be statistically similar (p > 0:05). The mean ±SD of total IIEF scores in the patient and control group were 60:14 ± 8:78 and 65:24 ± 5:52, respectively (p = 0:007). Although the mean IIEF-erectile function, orgasmic function and intercourse satisfaction scores in the patient group were significantly lower than the control group (p < 0:001, p = 0:004 and p = 0:001, respectively), the mean IIEF-desire score of the patients was significantly higher than the controls (p = 0:002). CONCLUSION: We found that the hormone profiles (except FSH and free T3) of the patients with gynecomastia were similar with the controls. However, gynecomastia adversely affected male sexual function. © 2016-IOS Press and the authors. All rights reserved.Item Assessment of bladder wall thickness in women with overactive bladder(AVES Ibrahim Kara, 2016) Üçer O.; Gümüş B.; Albaz A.C.; Pekindil G.Objective: To compare bladder wall thickness (BWT) between female patients with overactive bladder (OAB) and aged-matched healthy controls. Material and methods: Thirty-six female patients with OAB and 31 healthy women were enrolled in the present prospective observational study. Qmax and Qave were measured by using uroflowmetry in all of the women in the patient and control groups, and also maximum bladder capacity (MBC), post- void residual urine (PVRU), prevoiding and postvoiding BWT were measured by using transabdominal ultrasound. Lower urinary tract symptoms of the participants were assessed by using Overactive Bladder Version-8 (OABV8) and International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF). All of the data were statistically compared between the patient and control groups. In the patient group, the relationships between parameters were evaluated correlation analysis. Results: The mean age of the patients and controls were similar (respectively, 45.58±12.35 and 44.21±11.60 years (p=0.68). The mean pre- and post-voiding BWT, OAB-V8 and ICIQ-SF scores of the patients were significantly higher than the controls. In the patient group, the moderate positive correlations between BWT with Qmax (p=0.02) and Qave (p=0.02) were found. Conclusion: This study showed that the BWTs of the female patients with OAB are higher than those of healthy women. Further studies should investigate the changes in BWT of patients with OAB after treatment of OAB. © 2016 by Turkish Association of Urology.Item Reliability and Validity of the Turkish Language Version of the International Consultation on Incontinence Questionnaire - Male Lower Urinary Tract Symptoms(Korean Continence Society, 2016) Mertoglu O.; Üçer O.; Ceylan Y.; Bozkurt O.; Günlüsoy B.; Albaz A.C.; Demir Ö.ÖmerPurpose: Patients receiving treatment for benign prostate hyperplasia may have persistent storage symptoms. There has been increasing debate on the precision and accuracy of the International Prostate Symptom Score questionnaires over other questionnaires in evaluating all the complaints of lower urinary tract symptoms (LUTS). The aim of this study was to perform the validity and reliability analysis of the Turkish version of the Internatinal Consultation on Incontinence Questionnaire-Male LUTS (ICIQ-MLUTS). Methods: Linguistic validation was studied (i.e., translation and back translation). Intelligibility was completed between October 2013 and November 2013. Data was collected between November 2013 and March 2014. The stability and reliability of the form were measured with the Cronbach test. Results: In total, 117 male patients were included in the study. At the first visit, the mean age of the patients was 59 years (range, 18-84 years). For reliability, the Cronbach alpha value was 0.798, demonstrating the internal consistency of the form (r>0.7). The internal consistency of each question was examined separately and found to be over 0.7. For the evaluation of test-retest reliability, the test was administered to 116 patients for a second time with an interval of 2-4 weeks. The first and second test scores for each question were found to be correlated (r=0.741). Conclusions: ICIQ-MLUTS is a new questionnaire, which can be used for evaluating male LUTS in Turkey. We believe that the Turkish version of the ICIQ-MLUTS is an important breakthrough in our country.Item Assessment of proportion of hidden patients having symptoms of overactive bladder and why has it been hidden in female outpatients admitted to hospital(Korean Continence Society, 2016) Üçer O.; Demir Ö.; Zeren M.F.; Ceylan Y.; Çelen I.; Zümrütbaş A.E.; Temeltaş G.; Bozkurt O.; Günlüsoy B.; Çelik O.; Ekin G.; Mertoğlu O.Purpose: To determine the proportion of patients with undetected symptoms of overactive bladder by using the overactive bladder-validated 8 (OAB-V8) screening questionnaire and investigate these symptoms were undetected in female patients who were hospitalized. Methods: We invited 2,250 female patients hospitalized in the Aegean region of Turkey to answer a self-administered questionnaire. The questionnaire included questions on evidence of lower urinary tract symptoms (OAB-V8), relevant medical history, and demographic data. Patients with a total OAB-V8 score ≥ 8 were defined as having OAB symptoms. Results: The proportion of patients with OAB symptoms in this study was 40.6%. Nearly 57% of the patients with OAB symptoms had not been previously admitted to any hospital for lower urinary tract symptoms (LUTS). The two most common reasons why women with OAB symptoms did not admit themselves to a hospital because of LUTS were as follows: "I did not think I had a disease" and "The symptoms did not bother me," with a response rate of 74.7%. The mean OAB-V8 scores of the patients with these two responses were significantly lower than those of the other patients (P < 0.001). Conclusions: This is the first study to demonstrate a significant proportion of women with undetected OAB symptoms. The main reasons the women did not admit themselves to a hospital were their unawareness of the disease and because the LUTS were not bothersome. Public awareness programs on this disease may resolve this problem. © 2016 Korean Continence Society.Item The effect on the sensitivities of PSA and PSA-age volume score of IPSS and nocturia in predicting positive prostate biopsy findings(Pan African Urological Surgeons Association(PAUSA), 2017) Üçer O.; Müezzinoğlu T.; Çelen İ.; Temeltaş G.Objective The PSA-age volume (PSA-AV) score was calculated by multiplying the age and prostate volume and then dividing the total by the prebiopsy PSA level. The aim of this study was to evaluate the effect on the sensitivities of PSA and PSA-AV score of International Prostate Symptom Score (I-PSS) and nocturia in predicting positive prostate biopsy findings. Subjects and methods A total of 1302 biopsies data were divided into two groups according to presence/absence of nocturia. Of these biopsies, 452 biopsies data with I-PSS were also divided into three groups according to severity of I-PSS. The sensitivities, specificities, positive and negative predictive values of the PSA-AV and PSA in all the groups were calculated separately. Results Although the sensitivities of PSA and PSA-AV were similar in the patients with nocturia (94.1% and 95.8%, respectively), the sensitivity of PSA-AV (99.2%) was higher than PSA (91.8%) in the patients without nocturia. The sensitivities of PSA in mild, moderate and severe I-PSS group were found to be 100%, 92.9% and 95%, respectively (the sensitivities of PSA-AV were 100%, 94.4% and 88.2%, respectively). While severity of I-PSS was decreasing, although sensitivity of PSA-AV increased regularly, sensitivity of PSA was variable. Conclusions All our data shows that if we remove most of the factors which effect PSA such as age, prostate volume, prostatitis and BPH, we may increase the sensitivity of PSA for predicting positive prostate biopsy. Further PSA formulas contain of result of some tests (I-PSS, uroflowmetry or postvoiding residue urine) as well as age and prostate volume should increase the sensitivity and specificity of PSA for detecting prostate cancer. © 2016 Pan African Urological Surgeons’ AssociationItem Evaluation of sexual function in women with labia minora hypertrophy: A preliminary study; [Evaluación de la función sexual en las mujeres con hipertrofia en los labios vaginales menores: un estudio preliminar](Ediciones Doyma, S.L., 2018) Sir E.; Güngör M.; Üçer O.; Aksoy A.Objective: To compare the sexual functions in women with labia minora hypertrophy and age-matched healthy controls. Material and method: 43 patients with labia minora hypertrophy and 30 age-matched healthy controls were enrolled in the present study. The sexual functions of the women were evaluated by using the index of female sexual function (IFSF). Results: Mean ages of the patients and controls were 30.06 ± 7.11 and 31.34 ± 4.12 (p = 0.41), respectively. Mean total IFSF scores of the patients and controls were 24.18 ± 3.24 and 27.53 ± 4.43 (p < 0.05), respectively. The subscale scores of IFSF-lubrication, orgasm, satisfaction and pain in the patient group were significantly lower than in the control group (respectively, p < 0.001, p < 0.05, p < 0.001 and p < 0.05). There was no statistically significant difference between IFSF-arousal scores of the patient and control groups (p = 0.30). The mean IFSF-desire scores of the patient group was higher than the controls (p < 0.001). Labia minora hypertrophy was significantly associated with female sexual dysfunction (odds ratio [OR] = 14.97, 95% confidence interval [Cl] = [3.66–61.21], p < 0.001). Conclusion: This study suggests that patients with labia minora hypertrophy have poorer lubrication, satisfaction, pain, and orgasm scores on the IFSF scale compared to age-matched healthy controls. © 2017 Asociación Española de Andrología, Medicina Sexual y ReproductivaItem Long term follow-up results of ablation treatment for patients with small renal mass(John Wiley and Sons Inc, 2021) Gümüş B.H.; Albaz A.C.; Düzgün F.; Üçer O.; Temeltaş G.; Müezzinoğlu T.; Tarhan S.Objective: The aim of this study is to evaluate the outcome of ablation therapy in our clinic for the treatment of patients with a small renal mass Materials and Methods: We retrospectively evaluated the technic and follow-up data of 30 patients with 36 tumours who underwent Radiofrequency Ablation (RFA) and Microwave Ablation (MWA) in our clinic. Demographic data, ablation type, tumour characteristics, peroperative and postoperative complications and treatment success of the patients were evaluated. Results: A total of 36 tumours who underwent ablation treatments, 23 were treated with RFA, 13 with MWA. The mean tumour size was 28.9 ± 6.92 mm in RFA and 29.3 ± 7.70 mm in MWA. The mean follow-up period was 49.6 ± 24.7 months in patients with RFA and mean follow-up was 16 ± 8.05 months in MWA treatments. The overall success in MWA administration was calculated as 76.9%, while the overall success in RFA was 80%. Conclusion: Long-term oncologic efficacy of RFA appears to be successful in the treatment of T1a renal carcinomas. Further studies can be conducted to elucidate the influence of MWA on long-term oncological outcomes. © 2021 John Wiley & Sons LtdItem Mediterranean Diet and Overactive Bladder(Korean Continence Society, 2022) Bozkurt Y.E.; Temeltaş G.; Müezzinoğlu T.; Üçer O.Purpose: The relationship between nutrition and overactive bladder (OAB) has yet to be elucidated. Therefore, this study investigated the relationship between the Mediterranean diet and OAB. Methods: The 14-item Mediterranean Diet Adherence Screener (MeDAS) and Overactive Bladder-Validated 8-question Screener (OAB-V8), validated in Turkish, were administered to 500 patients over the age of 18 who presented to outpatient clinics other than urology outpatient clinics. Of those patients, 174 with chronic diseases and urinary tract infections (based on urinalysis and a detailed medical history) were excluded. Therefore, 326 patients' data were analyzed. Results: There was a negative correlation between the MeDAS and OAB-V8 scores. High OAB-V8 scores were associated with obesity (body mass index ≥ 30 kg/m2), being single, and a low education level. Conclusions: Dietary patterns represent a broader perspective on food and nutrient consumption and may therefore be more predictive of disease risk. The Mediterranean type should be recommended in the first-line treatment of patients with OAB symptoms. It is easily possible to determine the compliance of patients with this diet by using the 14-item MeDAS. Copyright © 2022 Korean Continence SocietyItem Can Aortic and Renal Arteries Calcium Scores Be New Factors to Predict Post-Operative Renal Function After Nephron Sparing Surgery?(Elsevier Inc., 2022) Akarken İ.; Bilen C.Y.; Özden E.; Gülşen M.; Üçer O.; Şahin H.Introduction: This study aims to investigate whether the calcification of renal arteries and aorta may be risk factors for developing chronic kidney disease (CKD) after Nephron sparing surgery (NSS). Materials and Methods: The patients that underwent either open or laparoscopic NSS from 2000 to 2019 in 4 different centers were retrospectively assessed. Of these patients, 328 had a non-contrast-enhanced computer tomography. Calcium scores of the renal arteries and abdominal aorta were measured in the non-contrast-enhanced images with the calcium score plugin (version 2.0) of Horos™. Univariate and multivariate logistic regression analysis was performed to determine significant risk factors for developing CKD at the last check-up. Roc curve analysis was performed to determine the optimal cut-off values of age and abdominal aorta calcium scores. Results: A total of 302 patients, of which 52 (16,6%) with CKD and 252 (83,4%) without CKD at the last check-up, were included in the analysis. The mean warm ischemia duration was significantly higher in patients with CKD (18,79±6,72 vs 16,38±5,57 minutes, p=0,016). The mean size of the tumor diameter and the number of the patients with ≥stage T1b were higher in the group with CKD (p=0,024 and 0,005, respectively). The median calcium scores of the aorta and renal arteries were higher in the group with CKD (p<0,001 and p<0,001, respectively). In multivariate analysis, age >60 years (OR:3,65, p=0,022), calcium score of the aorta (OR:4,07, p=0,029), tumor diameter (OR:1,03, p=0,026) and pre-operative CKD stage (OR:10,13, p<0,001) found the be significant factors for predicting last check-up CKD. Conclusion: The calcium score of the aorta may be used as an additional risk factor to predict post-operative CKD risk after NSS with sensitivity over 80%. © 2021Item Asymptomatic Giant Renal Calculi: Single-Session Percutaneous Nephrolithotomy—Images(Springer, 2023) Bozkurt Y.E.; Temeltaş G.; Üçer O.; Müezzinoğlu T.In a 55-year-old woman patient with a body mass index of 27 kg/m2, a giant staghorn kidney stone (10 × 6.4 × 8 cm) was detected in the right kidney on computed tomography, then the patient was treated with a single-session percutaneous nephrolithotomy, and there were no complications afterwards. © 2022, Association of Surgeons of India.Item Evaluating the effect of histopathological parameters of prostate adenocarcinoma on prognosis in radical prostatectomy specimens(2024) Tercan E.; Erbatu O.U.; Üçer O.; Metin S.; Ne E N.BACKGROUND: Over the past decade, significant updates have been made regarding the classification and grading of prostate adenocarcinoma in radical prostatectomy specimens, following decisions reached in international conferences and through impactful publications. These alterations are closely linked to patient prognosis. OBJECTIVES: Observe the incidence of these changes and their impact on patient prognosis. Additionally, investigate the relationship between histopathological and clinical parameters to assist in multidisciplinary treatment planning. DESIGN: Retrospective cohort study. SETTING: Tertiary university hospital. METHODS: Hematoxylin and eosin, along with immunohistochemistry stained sections, were reevaluated, and clinical information, including patient demographics, preoperative PSA levels, and patient follow-up were collected from patients who underwent radical prostatectomy at our center. SAMPLE SIZE: 182 patients. MAIN OUTCOME MEASURES: Biochemical recurrence. RESULTS: The study highlighted the negative prognostic effects of factors such as Gleason grade group, lymphovascular invasion, intraductal carcinoma, positive surgical margins, extraprostatic extension, pathological T stage, and seminal vesicle invasion. These factors are important determinants of recurrence-free survival in prostate adenocarcinoma patients. CONCLUSION: This study identified comedonecrosis and intraductal carcinoma as independent negative prognostic factors. A 3-mm cutoff for positive surgical margins was supported, while the current cutoff for extraprostatic extension may require reevaluation. The impact of cribriform pattern and ductal carcinoma appears to be influenced by the grade group. No independent relationship was found between the Gleason score/pattern on positive surgical margins or extraprostatic extension and prognosis. Further, large-scale studies with long-term follow-up are needed. LIMITATIONS: The study is limited by the relatively small number of patients for certain parameters.