MCBÜ Açıkerişim Sistemi :: Browsing by Author "Aşçibaşi K."

Browsing by Author "Aşçibaşi K."

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Reliability and validity of Turkish form of severity of acute stress symptoms scale; [DSM-5 Akut Stres Belirti Şiddeti Ölçeği Türkçe Formunun geçerliliği ve güvenilirliği]
(Cukurova University, Faculty of Medicine, 2017) Aşçibaşi K.; Çökmüş F.P.; Aydemir Ö.; Aydin Aşik E.; Herdem A.; Alçi D.; Öztekin S.; Sarikavak T.; Aydin O.; Balikçi K.; Çöldür E.Ö.; Yüzeren S.; Sücüllüoğlu Dikici D.; Akdeniz F.; Köroğlu E.
Objective: This study demonstrates the reliability and validity of the Turkish Form of Acute Stress Symptoms Scale which was developed according to DSM-5 criteria to measure the severity of acute stress disorder. Methods: This research was carried out with the patients who fulfilled the criteria of any stress related disorders according to DSM-5 criterion in inpatient and outpatient psychiatric clinics of Celal Bayar University, School of Medicine. Except for acute or post-traumatic stress disorders, patients with any other mental or physical disease were excluded. Fifty patients were included in the study. As the control group, 150 volunteers without any mental or physical diseases were invited. Beside Acute Stress Symptoms Scale, Peritraumatic Dissociative Experiences Questionnaire (PDEQ) which is the most commonly used self-rated instrument to rate the experience of recent trauma is utilized for concur-rent validity. In reliability analyses, internal consistency coefficient and item-total correlation coefficients were calcu-lated. In validity analyses, factor analysis and correlation analysis with PDEQ were performed. Results: The mean age of the study group was 32.1±12.0 years, and 57.7% of the sample group (n=116) were female. 31.3% of the group were college graduates, 36.3% primary school graduates, 29.9% is high school graduates. Disease duration in acute stress disorder group was 4.08±4.57 years. For the internal consistency of Acute Stress Symptoms Severity Scale, Cronbach’s alpha coefficient was found to be 0.95. Item-total score correlation coefficients were between 0.76 and 0.88 and all were statistically significant. For the exploratory factor analysis, sample adequacy was tested, Kaiser-Meier-Olkin (KMO) coefficients was 0.91 and Bartlett coefficient was 1388. Single-factor solution was obtained and the eigenvalue was 5.40, representing 77.8% of the total variance. Factor loadings of the items were between 0.82-0.92. The coefficient of correlation analysis with PDEQ was calculated as r=0.88. Area under the curve is found 0.99 as the result of ROC analysis. Conclusion: With these findings, it is shown that the severity of Acute Stress Symptoms Scale is reliable and valid for Turkish. © 2017 Anadolu Psikiyatri Derg. All rights reserved.
Reliability and validity of Turkish form of level 2 anxiety scale; [DSM-5 düzey 2 anksiyete ölçeği Türkçe formunun geçerliliği ve güvenilirliği]
(Cukurova University, Faculty of Medicine, 2017) Aydin Aşik E.; Çökmüş F.P.; Aydemir Ö.; Aşçibaşi K.; Herdem A.; Çöldür E.Ö.; Alçi D.; Sarikavak T.; Öztekin S.; Balikçi K.; Yüzeren S.; Aydin O.; Akdeniz F.; Sücüllüoğlu Dikici D.; Köroğlu E.
Objective: This study aims to demonstrate the reliability and validity of the Turkish Form of Level 2 Anxiety Scale developed according to DSM-5 criteria to measure the severity of panic disorder. Methods: This study was carried out with patients with a diagnosis of any anxiety disorder according to DSM-5 criteria who are under treatment in Celal Bayar University Faculty of Medicine Psychiatry inpatient or outpatient clinics. Patients with any mental or physical disease except for anxiety disorders were excluded. Accordingly, 54 patients with anxiety disorder were included in the study and these were distributed as panic disorder in seven patients, generalized anxiety disorder in two patients, agoraphobia in three patients, specific phobia in one patient, obsessive-compulsive disorder in two patients, somatization disorder in one patient and not otherwise specified anxiety disorder in 38 patients. As the healthy control group in 104 volunteers without any mental or physical disease were included. Beside Level 2 Anxiety Scale the most widely used self-rated scale, Spielberger’s State-Trait Anxiety Inventory was used for concurrent validity. In reliability analysis internal consistency coefficient and item-total correlation analysis; in validity analyses factor analysis and correlation analysis with the Spearman Correlation Analysis (SCA) was performed for validation. Results: The mean age of the study group was 28.23±11.7 years and 58.9% of the sample group (n=93) were female. 64.6% of the group were college graduates, 19.0% primary school graduates, 12.7% is also high school graduates. Disease duration of anxiety disorder group was 17.2±11.2 years. The internal consistency of the Level 2 Anxiety Scale was 0.94 and, item-total correlation coefficients of the Level 2 Anxiety Scale were between 0.68 and 0.88. In the exploratory factor analysis, for sample adequacy Kaiser- Meier-Olkin (KMO) coefficient was calculated as 0.90 and Bartlett coefficient was 1.08. Single-factor solution was obtained and the eigenvalue was 5.26, explaining 75.2% of the total variance. Factor loadings of the items were between 0.75 and 0.92. Coefficient of correlation analysis with SCA was calculated as r=0.45. Conclusion: These findings have been shown that the Level 2 Anxiety Scale is reliable and valid for Turkish. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
Reliability and validity of the Turkish version of DSM-5 level 2 anger scale; [DSM-5 İkinci Düzey Öfke Ölçeği Türkçe Formunun geçerliliği ve güvenilirliği]
(Cukurova University, Faculty of Medicine, 2017) Çöldür E.Ö.; Öztekin S.; Aydemir Ö.; Sücüllüoğludikici D.; Akdeniz F.; Yüzeren S.; Alçi D.; Balikçi K.; Çökmüş F.P.; Aydin O.; Sarikavak T.; Aşçibaşi K.; Herdem A.; Aydin Aşik E.; Köroğlu E.
Objective: The purpose of the present study was to investigate the reliability and validity of the Turkish Form of Level 2 Anger Scale. The scale was originally developed to measure the severity of anger regarding the DSM-5 criteria. Methods: This study was conducted in the Department of Psychiatry in Celal Bayar University Hospital. The participants were in- or out-patients diagnosed with any psychotic disorders according to the DSM-5. The exclusion criteria were comorbidity of other psychiatric disorders and/or physical diseases. The participants were 49 patients who were diagnosed with schizophrenia (n=40), schizoaffective disorder (n=3), and not otherwise specified psychotic disorder (n=6). One hundred and one volunteers without any mental or physical disease were also included to represent the healthy control. In the assesment beside Level 2 Anger Scale, 18-item Brief Psychiatric Rating Scale was used. In reliability analysis internal consistency coefficient and item-total correlation analysis were performed; for validity analysis exploratory factor analysis was performed. In concurrent validity correlation analyses between Level 2 Anger Scale and BPRS tension, hostility, uncooperativeness, and elated mood subscales were computed. In order to discriminate between the psychosis and the control group, group means of Anger Scale were compared with t-test. Results: The mean age of the study group was 26.0±10.3 and 52.7% of the sample group were female (n=79). 69.3% of them were graduated from university (n=104), 19.3% from high school (n=29), and 8% from elementary school. Disease duration of psychotic disorder group was 17.1±9.7 years. The internal consistency of the Level 2 Anger Scale was 0.91 and, item-total correlation coefficients were between 0.74-0.83. For the exploratory factor analysis of sample adequacy of Level 2 Anger Scale Kaiser-Meğer-Olkin (KMO) coefficients 0.81 and Bartlett coefficient 1.03 was found. Single-factor solution was obtained and the eigenvalue is 3.79, representing 75.80% of the total variance. Factor loadings of the items of the scale were between 0.83-0.90.The mean of score was 5.09±0.72 in the psychosis group while it was calculated as 3.65±0.36 in the control group. There was a statistically significant difference between the groups. There were moderate to high correlations between Level 2 Anger Scale and BPRS tension, hostility, uncooperativeness, and elated mood. Conclusion: Results demonstrated that the Turkish version of Level 2 Anger Scale is a valid and reliable. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
Reliability and validity of Turkish form of DSM-5 mania scale; [DSM-5 mani ölçeği Türkçe formunun geçerliliği ve güvenilirliliği]
(Cukurova University, Faculty of Medicine, 2017) Öztekin S.; Alçi D.; Aydemir Ö.; Çökmüş F.P.; Aydin O.; Balikçi K.; Sarikavak T.; Akdeniz F.; Sücüllüoğlu Dikici D.; Aşçibaşi K.; Çöldür E.Ö.; Yüzeren S.; Herdem A.; Aşik E.A.; Köroğlu E.
Objective: This study aimed to demonstrate the reliability and validity of the Turkish form of DSM-5 Mania Scale which was developed according to DSM-5 criteria to measure the severity of mania. Methods: This study was conducted with 50 patients who meet the diagnostic criteria of bipolar disorders according to DSM-5 criteria who are within manic or euthymic episode. The patients were under treatment at inpatient and outpatient clinics of Psychiatry Department of Celal Bayar University, Medicine Faculty. Patients with any mental or physical disease except bipolar disorders were excluded. Sixty-three volunteers without any mental or physical disease were in- cluded as healthy control group. Beside DSM-5 Mania Scale the most widely used scale Young Mania Rating Scale (YMRS) was used for concurrent validity. In reliability analyses internal consistency coefficient and item-total correlation analysis; in validity analyses factor analysis and correlation analysis with the Pearson Correlation Analysis were performed. Results: The mean ages of the bipolar disorders group (n=50) and healthy control group (n=63) were respectively 30.9±13.6 and 22.4±5.8. 53.7% of the sample group (n=58) were female. Disease duration of bipolar disorder group was 7.2±7.9 years. The internal consistency of the DSM-5 Mania Scale was 0.91 and, item-total correlation coefficients of the DSM-5 Mania Scale were between 0.67 and 0.85. In the explanatory factor analysis, for sample adequacy Kaiser- Meier-Olkin (KMO) coefficient was calculated as 0.85 and Bartlett coefficient was 389.51. Single-factor solution was obtained and the eigenvalue was 3.69, explaining 73.8% of the total variance. Factor loadings of the items were between 0.77-0.91. Significant and high levels of correlation were determined between YMRS and DSM-5 Mania Scale (r=0.78). Conclusion: These findings have been shown that the DSM-5 Mania Scale is reliable and valid for Turkish. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
Reliability and validity of turkish form of DSM-5 self-rated level 1 cross-cutting symptom scale-adult version; [DSM-5 birinci düzey kesitsel belirti ölçeği türkçe erişkin formunun geçerliliği ve güvenilirliği]
(Cukurova University, Faculty of Medicine, 2017) Çökmüş F.P.; Balikçi K.; Aydemir Ö.; Akdeniz F.; Sücüllüoğlu Dikici D.; Yüzeren S.; Alçi D.; Öztekin S.; Çöldür E.Ö.; Aydin O.; Sarikavak T.; Aşçibaşi K.; Herdem A.; Aydin Aşik E.; Köroğlu E.
Objective: The aim of this study is to demonstrate the reliability and validity of the Turkish Form of DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Scale Adult Version which is developed according to DSM-5 criteria to measure the severity of general symptomatology. Methods: This research was carried out with patients and their relatives who fulfilled the criteria of any psychiatric disorder according to DSM-5 criteria in inpatient and outpatient psychiatric clinics of Manisa Celal Bayar University, School of Medicine and healthy control group without any mental or physical disease. Accordingly, the distribution of psychiatric diagnosis of the patients were as follows: 39 patients with major depressive disorder, three patients with panic disorder, two patients with obsessive-compulsive disorder, four patients with schizophrenia, two patients with schizoaffective disorder, seven patients with BTA anxiety disorder, two patients with conversion disorder and post-traumatic stress disorder in one patient. Beside Level 1 Cross-Cutting Symptom Scale, the most widely used for general semptomatology self-rated scale, Symptom Check List-90-Revised Form (SCL-90-R) was used for concurrent validity. In reliability analysis internal consistency coefficient and item-total correlation analysis; in validity analyses exploratory factor analysis and correlation analysis with the SCL-90-R and subscales was performed for validation. Results: This research was carried out with 206 volunteers. 61.2% of the sample group (n=126) were female and the mean age of the study group was 35.1±11.2 years. 29.6% of the group were college graduates, 36.4% primary school graduates, 7.8% middle school graduates and 23.3% were also high school. The internal consistency of the Level 1 Cross-Cutting Symptom Scale was 0.94 and, item-total score correlation coefficients of the Level 1 Cross-Cutting Symptom Scale were between 0.30-0.79. In the exploratory factor analysis, for sample adequacy Kaiser-Meier-Olkin (KMO) coefficient was calculated as 0.92 and Bartlett coefficient was 3007.76. Three-factor solution was obtained, representing 60.8% of the total variance. In the analysis of the correlation between the subscales of SCL-90-R and subscales of the Level 1 Cross-Cutting Symptom Scale were as follows; for depression r=0.72, for anxiety r=0.80, for somatization r=0.72, for psychosis r=0.70, for obsessive compulsive symptoms r=0.68, for personality r=0.72, for suicide r=0.53, for sleep r=0.76, for anger r=0.64 and for the total score r=0.87 was obtained. Conclusion: These findings show that the Level 1 Cross-Cutting Symptom Scale is reliable and valid for Turkish. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
Reliability and validity of Turkish version of DSM-5 level 2 depression adult scale; [DSM-5 düzey 2 depresyon erişkin ölçeği Türkçe formunun geçerliliği ve güvenilirliği]
(Cukurova University, Faculty of Medicine, 2017) Aydin Aşik E.; Çöldür E.Ö.; Aydemir Ö.; Aşçibaşi K.; Herdem A.; Alçi D.; Sarikavak T.; Çökmüş F.P.; Öztekin S.; Balikçi K.; Yüzeren S.; Aydin O.; Akdeniz F.; Sücüllüoğlu Dikici D.; Köroğlu E.
Objective: This study aims to demonstrate the reliability and validity of Turkish version of DSM-5 Level 2 Depression Adult Scale which was developed to measure the severity of depression. Methods: The study group included 51 in or out-patients who met the criteria for major depressive disorder according to DSM-5. Sixty-five volunteers without any mental or physical disease were also recruited as a control group. Beck Depression Inventory (BDI), which is the most widely used self-report scale, was used for concurrent validity. Internal consistency coefficient and item-total correlation analysis were performed for reliability. Exploratory factor analysis was used for validity, as BDI was used for concurrent validity. Results: Mean age was 40.5±11.4 in the patient group and 21.8±4.9 years in the control group, respectively. 62.1% of the sample group (n=72) were female. 59.5% of the group were college graduates, 16.4% were primary school graduates and 14.7% were high school graduates. Disease duration for major depressive disorder was 13.5±10.5 years for the patient group. The internal consistency of the Level 2 Depression Adult was 0.96. Item-total correlation coefficients were between 0.71 and 0.90. For the exploratory factor analysis of sample adequacy of DSM-5 Level 2 Depression Adult Scale, Kaiser-Meger-Olkin (KMO) coefficient and Bartlett coefficient was calculated as 0.91 and 1026.62, respectively. Single-factor solution was obtained with an eigen value of 6.27, representing 78.3% of the variance. Factor loadings of the items were between 0.77 and 0.92. Correlation coefficient of Level 2 Depression Adult Scale with BDI was found as r=0.76. Conclusion: The Turkish version of DSM-5 Level 2 Depression Adult Scale is reliable and valid. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
Reliability and validity of Turkish form of repetitive thoughts and behaviors scale; [DSM-5 Yineleyici Düşünceler ve Davranışlar Ölçeği Türkçe Formunun geçerliliği ve güvenilirliği]
(Cukurova University, Faculty of Medicine, 2017) Aşçibaşi K.; Öztekin S.; Aydemir Ö.; Aydin Aşik E.; Poyraz Çökmüş F.; Herdem A.; Alçi D.; Sarikavak T.; Aydin O.; Balikçi K.; Çöldür E.Ö.; Yüzeren S.; Sücüllüoğlu Dikici D.; Akdeniz F.; Köroğlu E.
Objective: This study demonstrates the reliability and validity of the Turkish form of Repetitive Thoughts and Behaviors Scale (RTBS) which is developed according to DSM-5 criteria to measure the severity of obsessive-compulsive disorders (OCD). Methods: This research was carried out with 30 patients who fulfilled the criteria of obsessive compulsive disorders according to DSM-5 criterion in inpatient and outpatient psychiatric clinics of Celal Bayar University, School of Medicine. As the control group, 30 volunteers without any mental or physical diseases were invited. Besides RTBS, Maudsley Obsessive Compulsive Questionnaire (MOCQ) which is the most commonly used self-report scale was used for concurrent validity. In reliability analyses, internal consistency coefficient and item-total correlation coefficients were calculated. In validity analyses, factor analysis and correlation analysis with MOCQ were performed as well as ROC analysis. Results: The mean age of the study group was 31.2±9.7 years, and 65% of the sample group (n=39) were female. 56.7% of the group were college graduates, 25% high school graduates, 18.3% primary school graduates. Disease duration in the obsessive-compulsive disorder group was 7.5±6.1 years. The internal consistency of the RTBS 0.97 and, item-total correlation coefficients of the RTBS be-tween 0.86 and 0.95 was obtained. For the exploratory factor analysis, sample adequacy was tested, Kaiser-Meier-Olkin (KMO) coefficient was 0.87 and Bartlett’s coefficient was 436.89. Single-factor solution was obtained and the eigenvalue was 4.50, representing 90.1% of the total variance. Factor loadings of the items were between 0.91-0.97. The coefficient of correlation analysis with MOCQ was calculated as r=0.71. The area under the curve in ROC analysis was 0.93. Conclusion: With these findings, it is shown that RTBS is reliable and valid for Turkish Form. © 2017 Anadolu Psikiyatri Derg. All rights reserved.
Reliability and validity of Turkish form of sleep disorder scale; [DSM-5 Uyku Bozukluğu Ölçeği Türkçe Formunun geçerliliği ve güvenilirliği]
(Cukurova University, Faculty of Medicine, 2017) Yüzeren S.; Herdem A.; Aydemir Ö.; Aydin O.; Balikçi K.; Sarikavak T.; Akdeniz F.; Sücüllüoğlu Dikici D.; Aşçibaşi K.; Çöldür E.; Alçi D.; Öztekin S.; Aydin Aşik E.; Köroğlu E.
Objective: This study, demonstrate the reliability and validity of the Turkish form of DSM-5 Sleep Disorder Scale which improved according to DSM-5 criteria to measure the intensity of sleep disorder. Methods: This study were carried out with patients fulfilling the diagnosis of any sleep disorder according to DSM-5 criteria and who are undergoing treatment in Celal Bayar University Hospital sleep medicine inpatient or outpatient clinic. Patients with any mental or physical disease except for anxiety disorders were excluded. As a result, 50 patients with sleep disorder were included in the study and diagnoses of OSAS in 41 patients, primer insomnia in five patients, parasomnia in three patients and narcolepsia in one patient were made. Without any mental or physical disease in 50 volunteers formed the control group. Beside the DSM-5 Sleep Disorder Scale, the most widely used scale for sleep disorders, Pittsburgh Sleep Disorder Index (PSQI), was used for validation. Internal consistency coefficient and item-total score correlation analysis for reliability analysis; factor analysis and correlation analysis with the PSQI, and ROC analysis for discrimination between the sleep disorder and healthy control group for validity were performed. Results: The mean age of the study group was 39.3±15.8 years and 47.0% of the sample group (n=47) were female. 55.0% of the group were college graduates, 22.0% primary school graduates, 18.0% were high school graduates. Disease duration of sleep disorder group was 16.8±12.6 years. The internal consistency of the DSM-5 Sleep Disorder Scale was 0.91 and, item-total score correlation coefficients of the DSM-5 Sleep Disorder Scale were between 0.61 and 0.81. For the factor analysis, the sample adequacy of DSM-5 Sleep Disorder Scale was determined with Kaiser-Meier-Olkin (KMO) analysis where the coefficient was 0.91 and Bartlett analysis where chi-square was 1.54. Single-factor solution was obtained and the eigenvalue is 5.07 representing 63.4% of the total variance. Factor loadings of the items of the scale were between 0.69-0.87. Coefficient of correlation analysis with PSQI was calculated as r=0.727. In the ROC analysis, the area under the curve was obtained as 0.76. Conclusion: These findings have been shown that the DSM-5 Sleep Disorder Scale is reliable and valid for Turkish. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
Reliability and validity of Turkish form of agoraphobia scale; [DSM-5 agorafobi ölçeği Türkçe formunun geçerliliği ve güvenilirliği]
(Cukurova University, Faculty of Medicine, 2017) Aydin O.; Çöldür E.Ö.; Aydemir Ö.; Balikçi K.; Çökmüş F.P.; Öztekin S.; Herdem A.; Aşçibaşi K.; Sarikavak T.; Akdeniz F.; Alçi D.; Yüzeren Başsivri S.; Sücüllüoğlu Dikici D.; Aydin Aşik E.; Köroğlu E.
Objective: The purpose of the present study was to investigate the validity and reliability of the Turkish Form of the Agoraphobia Scale. The scale was originally developed to measure the severity of agoraphobia regarding the DSM- 5 criteria. Methods: This study was conducted at the Department of Psychiatry in Celal Bayar University Hospital. The participants were in- or out-patients diagnosed with any anxiety disorder according to the DSM-5. The exclusion criteria were comorbidity of other psychiatric disorders and/or physical diseases. Accordingly, 50 patients with anxiety disorder were included in the study and these were distributed as panic disorder in 14 patients, generalized anxiety disorder in 10 patients, agoraphobia and obsessive-compulsive disorder in four patients, post-traumatic stress disorder in one patient and not otherwise specified anxiety disorder in 17 patients. One hundred and three volunteers without any mental or physical disease were also included to represent the healthy control. Additionally the most widely used self-rated scale of the Spielberger’s State-Trait Anxiety Inventory was used for concurrent validity. Reliability analysis was performed to examine the internal consistency of the Turkish version of the scale. Additionally, item-total correlations were reported. In terms of examining the validity of the scale, subgroup validity analysis was conducted to investigate whether two groups of patients differ in their scores on the scale. ROC analysis was also performed. Results: The mean age of the study group was 29.0±11.8 and 60.1% of the sample group (n=92) were female. 66.0% of the group were college graduates, 19.0% primary school graduates, 15.0% is also high school graduates. Disease duration of anxiety disorder group was 17.1±9.7 years. The internal consistency of the Agoraphobia Scale was 0.95 and, item-total score correlation coefficients of the Agoraphobia Scale were between 0.66 and 0.87. In the explanatory factor analysis, for sample adequacy Kaiser-Meier-Olkin (KMO) coefficient was 0.92 and Bartlett coefficient was 1.57. Single-factor solution was obtained and the eigenvalue was 7.16, explaining 71.68% of the total variance. Factor loadings of the items were between 0.71 and 0.90. Coefficient of Spearman correlation analysis was r=0.31. Conclusion: Results demonstrated that the Turkish version of the Agoraphobia Scale was a valid and reliable instrument which may serve as useful in guiding future research that aims to measure agoraphobia severity. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
Validity and reliability of the turkish version of the clinician rated severity of autism spectrum and social communication disorders scale; [DSM-5 klinisyen tarafından puanlanan otizm spektrum ve toplumsal İletişim bozukluğu Şiddeti Ölçeği türkçe formunun geçerliliği ve güvenilirliği]
(Cukurova University, Faculty of Medicine, 2017) Aydin O.; Çökmüş F.P.; Aydemir Ö.; Herdem A.; Balikçi K.; Sücüllüoğlu Dikici D.; Öztekin S.; Akdeniz F.; Sarikavak T.; Aşçibaşi K.; Çöldür E.; Alçi D.; Aşik E.A.; Yüzeren S.; Köroğlu E.
Objective: The purpose of the present study was to investigate the validity and reliability of the Turkish form of the Clinician Rated Severity of Autism Spectrum and Social Communication Disorders Scale. The scale was originally developed to measure the severity of autism spectrum and social communication disorders regarding the DSM-5 criteria. Methods: The study was conducted in the Department of Psychiatry at Celal Bayar University Hospital. The participants were in- or out-patients diagnosed with any psychotic disorders according to DSM-5. The exclusion criteria were comorbidity of other psychiatric disorders and/or physical diseases. The study was carried out with a total of 49 patients who were diagnosed with schizophrenia (n=40), schizoaffective disorder (n=3), and not otherwise specified psychotic disorder (n=3). One hundred and one volunteers without any mental or physical disease were also included to represent the healthy control. Reliability analysis was performed to examine the internal consistency of the Turkish version of the scale. Additionally, item-total correlations were reported. In validity analyses, comparison of the total score of the scale in the patient and control groups was evaluated for the discriminative validity. ROC analysis was also performed. Results: 52.7% of the sample were male (n=79). 69.3% of them were graduated from university (n=104), 19.3% from high school (n=29), and 8% from elementary school (n=12). The mean age of the study group was 26.3±10.3 years. Disease duration of psychotic disorder group was 18,29±6.43 years. The internal consistency of the Autism Spectrum and Social Communication Disorder Scale was 0.81. Furthermore, item-total correlations revealed that all items in the scale contributed to the consistency of scores with item-total correlations approaching 0.70. The mean score of the scale in the patient group on the scale was 1.42 whereas the mean score of the healthy group was 0.0. The t-test analysis indicated that there was a statistically significant difference between the sample group and the healthy group in their scores on the scale. In the ROC analysis, the area under the curve was 0.84. Conclusion: Results demonstrated that the Turkish version of Autism Spectrum and Social Communication Disorder Scale was a valid and reliable instrument which may serve as useful in guiding future research that aims to understand autism spectrum and social communication disorder. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
Reliability and validity of Turkish form of DSM-5 severity measure for specific phobia; [DSM-5 Özgül Fobi Şiddet Ölçeği Türkçe Formunun geçerliliği ve güvenilirliği]
(Cukurova University, Faculty of Medicine, 2017) Öztekin S.; Aydin O.; Aydemir Ö.; Çökmüş F.; Sarikavak T.; Sücüllüoğludikici D.; Aşçibaşi K.; Akdeniz F.; Alçı D.; Çöldür E.Ö.; Yüzeren S.; Herdem A.; Aydinaşik E.; Köroğlu E.
Objective: This study aimed to demonstrate the reliability and validity of the Turkish form of DSM-5 Severity Measure for Specific Phobia Scale which was developed according to DSM-5 criteria to measure the severity of specific phobia. Methods: This study was carried out with patients with a diagnosis of any anxiety disorder according to DSM-5 criteria who are under treatment in Celal Bayar University Faculty of Medicine Psychiatry Inpatient or Outpatient Clinics. Patients with any mental or physical disease except for anxiety disorders were excluded. Accordingly, 50 patients with anxiety disorder were included in the study. One hundred and three volunteers without any mental or physical disease were included as healthy control group. Beside DSM-5 Severity Measure for Specific Phobia Scale the most widely used self-rated scale, Spielberger’s State-Trait Anxiety Inventory was used for concurrent validity. In reliability analyses internal consistency coefficient and item-total correlation analysis; in validity analyses factor analysis and correlation analysis with the Pearson Correlation Analysis were performed. Results: The mean age of the study group was 29.0±11.8 and 60.1% of the sample group (n=92) were female. 66.0% of the sample group were college graduates, 12.4% high school graduates, 21.6% were also primary school graduates. Disease duration of anxiety disorder group was 5.8±7.0 years. The internal consistency of the DSM-5 Severity Measure for Specific Phobia Scale was 0.79 and item-total correlation coefficients were between 0.33 and 0.78. In the explanatory factor analysis, for sample adequacy Kaiser-Meier-Olkin coefficient was calculated as 0.88 and Bartlett coefficient was 1.01. Double-factor solution was obtained and the eigenvalues were 5.45 and 1.26, explaining 67.20% of the total variance. Factor loadings of the items were between 0.43 and 0.88. Coefficient of correlation analysis with Spielberger’s State-Trait Anxiety Inventory was calculated as r=0.36. Conclusion: These findings have been shown that the DSM-5 Severity Measure for Specific Phobia Scale is reliable and valid for Turkish. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
Reliability and validity of Turkish form of panic disorder scale; [DSM-5 panik bozukluğu ölçeği Türkçe formunun geçerliliği ve güvenilirliği]
(Cukurova University, Faculty of Medicine, 2017) Balikçi K.; Herdem A.; Aydemir Ö.; Aydin O.; Çökmüş F.P.; Sücüllüoğlu Dikici D.; Öztekin S.; Akdeniz F.; Sarikavak T.; Aşçibaşi K.; Çöldür E.Ö.; Alçi D.; Aydin Aşik E.; Yüzeren S.; Köroğlu E.
Objective: This study is to demonstrate the reliability and validity of the Turkish form of Panic Disorder Scale developed according to DSM-5 criteria to measure the severity of panic disorder. Methods: This study was carried out with patients with a diagnosis of any anxiety disorder according to DSM-5 criteria who are under treatment in Celal Bayar University Faculty of Medicine Psychiatry Inpatient or Outpatient Clinics. Patients with any mental or physical disease except for anxiety disorders were excluded. Accordingly, 50 patients with anxiety disorder were included in the study and these were distributed as panic disorder in 14 patients, generalized anxiety disorder in 10 patients, agoraphobia and obsessive-compulsive disorder in four patients, post-traumatic stress disorder in one patient and not otherwise specified anxiety disorder in 18 patients. As the healthy control group 103 volunteers without any mental or physical disease were included. Beside Panic Disorder Scale the most widely used self-rated scale, Spielberger’s State-Trait Anxiety Inventory was used for concurrent validity. In reliability analysis internal consistency coefficient and item-total correlation analysis; in validity analyses factor analysis and correlation analysis with the Spearman Correlation Analysis (SCA) was performed for validation. Results: The mean age of the study group was 29.0±11.8 years and 60.1% of the sample group (n=92) were female. 66.0% of the group were college graduates, 19.0% primary school graduates, 15.0% is also high school graduates. Disease duration of anxiety disorder group was 17.1±9.7 years. The internal consistency coefficient of the Panic Disorder Scale was 0.96 and, item-total correlation coefficients of the Panic Disorder Scale were between 0.68 and 0.88.In the exploratory factor analysis, for sample adequacy Kaiser-Meier-Olkin (KMO) coefficient was calculated as 0.92 and Bartlett coefficient was 1.57. Single-factor solution was obtained and the eigenvalue was 7.38, explaining 73.8% of the total variance. Factor loadings of the items were between 0.73 and 0.91. Coefficient of correlation analysis with SCA was calculated as r=0.32. Conclusion: These findings have been shown that the Panic Disorder Scale is reliable and valid for Turkish. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
Reliability and validity of Turkish version of DSM-5 depression scale; [DSM-5 depresyon ölçeği Türkçe formunun geçerliliği ve güvenilirliği]
(Cukurova University, Faculty of Medicine, 2017) Sücüllüoğlu Dikici D.; Aşçibaşi K.; Aydemir Ö.; Balikçi K.; Akdeniz F.; Çöldür E.Ö.; Yüzeren S.; Alçi D.; Çökmüş F.P.; Öztekin S.; Aydin O.; Sarikavak T.; Herdem A.; Aydin Aşik E.; Köroğlu E.
Objective: This study aims to demonstrate the reliability and validity of Turkish version of DSM-5 Depression Scale which was developed to measure the severity of depression. Methods: The study group included 50 in- or out-pa- tients who met the criteria for major depressive disorder according to DSM-5. Sixty-three healthy volunteers without any mental or physical disease were also recruited as a control group. Beck Depression Inventory (BDI), which is the most widely used self-report scale, was used for concurrent validity. Internal consistency coefficient Cronbach alfa and item-total correlation analysis were performed for reliability. Exploratory factor analysis was used for validity, as BDI was used for concurrent validity. Results: Mean age was 39.2±11.3 and 22.4±5.8 years in the patient and control group, respectively. Sixty-one percent of the sample group (n=66) were female. 64.8% of the group were college graduates, 19% were primary school graduates and 18.5% were high school graduates. Disease duration for major depressive disorder was 3.3±5.6 years for the patient group. For the internal consistency Cronbach alfa coefficient of the DSM-5 Depression Scale was 0.91. Item-total correlation coefficients were between 0.60-0.83. For the exploratory factor analysis of sample adequacy of DSM-5 Depression Scale, Kaiser-Meier-Olkin (KMO) coefficient and Bartlett coefficient was calculated as 0.91 and 608.18, respectively. Single-factor solution was obtained with an eigenvalue of 5.44, representing 60.4% of the variance. Factor loadings of the items were between 0.66-0.80. Correlation coefficient of DSM-5 Depression Scale with BDI was found as r=0.88. Conclusion: The Turkish version of DSM-5 Depression Scale is reliable and valid. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
Reliability and validity of Turkish version of DSM-5 psychosis scale; [DSM-5 psikoz ölçeği Türkçe formunun geçerliliği ve güvenilirliliği]
(Cukurova University, Faculty of Medicine, 2017) Herdem A.; Sücüllüoğlu Di̇ki̇ci D.; Aydemi̇r Ö.; Aydin O.; Aşçibaşi K.; Aydin Aşik E.; Sariikavak T.; Akdeni̇balikçi K.; Çöldür E.Ö.; Alçi D.; Çökmüş F.P.; Yüzeren S.; Öztekïn S.; Akdenïz F.; Köroğlu E.
Objective: In this study we evaluated the reliability and validity of the Turkish version of DSM-5 Psychosis Scale developed in order to evaluate severity of psychosis in adult patients. Methods: This study was carried out with patients who met the diagnostic criteria for any psychotic disorder according to DSM-5 criteria and who are undergoing treatment in the inpatient and outpatient wards of Psychiatry Department of Celal Bayar University Medical School. Except for psychotic disorders patients with any mental or physical disease were excluded. A total of 49 patients (40 patients with schizophrenia, six patients with not otherwise specified psychotic disorder, three patients with schizoaffective disorder) were included in the study. One hundred and one volunteers without any mental or physical disease were included as the healthy control group. Reliability analysis was based on internal consistency and item-total score correlation. Validity analysis was based on exploratory factor analysis, comparison of mean scores of the patient and healthy control groups and ROC analysis. Results: The mean age of the study group was 26.0±10.3 years and 52.7% of the sample group (n=79) were female. Sixty-nine point three percent of the study group were college graduates, 8% primary school graduates, 19.3% is also high school graduates. Mean disease duration was 17.1±9.7 years in the psychotic disorder group. The internal consistency of the Psychosis Scale was 0.91 and, item-total correlation coefficients of the Psychosis Scale were between 0.25 and 0.82. In the factor analysis, for sample adequacy Kaiser- Meier-Olkin (KMO) coefficient was found as 0.81 and Bartlett coefficient as 1.03. Single-factor solution was obtained and the eigenvalue is 5.12, representing 64.0% of the total variance. Factor loadings of the items of the scale were between 0.33 and 0.88. The mean of score was 11.00±5.20 in patient group while it was calculated as 0.21±1.21 in control group. The area under the curve was calculated as 0.98 in the ROC analysis. Conclusion: These results indicate that the Turkish version of Psychosis Scale is reliable and valid. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
Relationships between nicotine craving, orexin-leptin levels and temperament character traits among non-treatment seeking health professionals
(Taylor and Francis Ltd., 2018) Aşçibaşi K.; Deveci A.; Cengiz Özyurt B.; Oran Pirinçcioğlu A.; Taneli F.
BACKGROUND: Repeated cigarette use in individuals generally occurs due to the craving for smoking. Orexin-leptin hormones and temperament character traits are thought to be important factors affecting nicotine craving. OBJECTIVE: The aims of this study were to determine orexin-leptin blood levels, which appear in nicotine deprivation, in health professionals who were diagnosed as having tobacco use disorder in accordance with the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V) and to assess the temperament-character traits of the same group and to provide biologic and psychotherapeutic data for the treatment of tobacco abuse. METHODS: The study sample consisted of faculty of medicine students and resident physicians who were smokers (n = 40). The control group comprised medical students and resident physicians who were non-smokers (n = 40). The Sociodemographic and Clinical Information Form, DSM-IV SCID-I Clinical Version, and Temperament and Character Inventory (TCI) were applied to both groups. Substance Craving Scale (SCS) and Fagerstrom Test for Nicotine Dependence were applied only smoking group. Blood samples were taken for plasma orexin and serum leptin levels for both groups. RESULTS: The plasma orexin levels were lower in the smokers group (p <.001). No statistically significant relations were determined between the SCS and plasma orexin and serum leptin levels in the smoking group. No significant differences were determined between the leptin (U = 119.5, p =.33) and orexin (U = 99, p =.11) levels of the heavy and very heavy smokers. The total points of novelty seeking (NS), and NS3 and NS4 subscale points in the TCI of the smoking group (p =.003, p =.003, p =.002), and the self-directedness (SD) SD2 and SD5 (p =.02, p =.01) subscale points, and total cooperativeness points (TC), and C4 and C5 subscale points (p =.001, p =.002, p =.001) of the non-smoking group were found as high. CONCLUSIONS/IMPORTANCE: Differences were detected between the smokers and non-smokers in TCI scale subgroups and in terms of orexin levels. These results will greatly assist in the fight against craving that appears as a result of smoking cessation. Orexin appears to be more specific for nicotine craving than leptin. It seems more likely that the quest for the treatment of craving will continue through orexin. Temperament and personality traits are important for determining psychotherapeutic and supportive approaches to the release of tobacco and tobacco products. A number of studies investigating monoaminergic mechanisms indirectly related to orexin and leptin are required to research temperament, which has a greater genetic burden. © 2018, © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
Evaluation of psychosocial functioning in the acute treatment term of major depressive disorder: A 16-week multi-centered follow-up study
(Elsevier B.V., 2021) Altunsoy N.; Di̇ki̇ci̇ D.S.; Çökmüş F.P.; Özkan H.M.; Aşçibaşi K.; Alçi D.; Kuru E.; Yüzeren S.; Aydemi̇r Ö.
Objective: Major depressive disorder is the leading cause of non-fatal burden, and disability in adulthood. Even though depression is well-treated in the acute term,psychosocial functioning does not get back to the premorbid level most of the time. In this present study, it is aimed to evaluate the outcome of the acute term treatment of major depressive disorder in terms of psychosocial functioning. Methods: The study is an open-label, observational, multi-center follow-up study for four months of patients with major depressive disorder according to DSM-5. Patients were evaluated with Montgomery Asberg Depression Rating Scale (MADRS), Sheehan Disability Scale (SDS) and Short Form-36 (SF-36) at the beginning, and at the 2., 4., 8., 12. and 16.weeks. Results: 100 patients were invited to the study and 56 patients completed the study.As a result of the treatment, the mean MADRS and SDS scores decreased significantly. All domains of SF-36 were improved significantly with the treatment. Unfortunately patients suffering from MDD could not reach the normative data,especially on the domains of social functioning, role emotional, pain, and general health perception. Treatment outcomes show that SNRI users presented higher scores on the domains of pain and physical functioning. However SSRI users showed better outcomes on the domains of mental health and vitality. Conclusion: Our research corroborated that even patients gain symptomatic remission in MDD treatment, psychosocial dysfunction persists. It is also concluded that different antidepressant options may act differently on treatment outcomes. © 2021 Elsevier B.V.
Seasonality in bipolar disorder: Impact on mood symptoms, psychosocial functioning, neurocognition, and biological rhythm; [Bipolar Bozuklukta Mevsimsellik: Duygudurum Belirtilerine, Psikososyal İşlevselliğe, Nörokognisyon ve Biyolojik Ritim Üzerine Etkisi]
(Turkish Neuropsychiatric Society, 2021) Çökmüş F.P.; Aşçibaşi K.; Sücüllüoğlu Dikici D.; Çöldür E.Ö.; Avci E.; Aydemir Ö.
Introduction: Even though an increase in the number of hospital admissions for manic and depressive periods at certain times of the year is reported in bipolar disorder (BD), mood symptoms do not show a seasonal variation. We aimed to find out the possible causes of increased hospital admissions of BD patients in certain periods of the year. Methods: The study was carried out in four centers in Turkey. The patient group consisted of 41 persons with a diagnosis of BD in remission. The healthy control (HC) group consists of 37 persons. The selected evaluation times are fall equinox (September 23), spring equinox (March 21), summer solstice (June 21) and winter solstice (December 21). For mood symptoms, Hamilton Depression Rating Scale and Young Mania Rating Scale; for functioning Functioning Assessment Short Test; for neurocognition Stroop Test (ST) and Rey Auditory Verbal Learning Test (RAVLT), for biological rhythm Biological Rhythms Interview of Assessment in Neuropsychiatry, and Seasonal Pattern Assessment Questionnaire were used. Results: In terms of mood symptoms no seasonal variation was found. Across all four periods of assessment of BD group, statistically significant variation was only observed in the instant recall, learning and recognition domains of RAVLT and word test and color test domains of ST; however, it was not sufficient to distinguish the BD group separating from the control group. Conclusions: In terms of mood symptoms, psychosocial functionality, biological rhythm, neurocognition, no seasonal variation was demonstrated that could distinguish the BD group from the HC group. © 2020 by Turkish Association of Neuropsychiatry.
The Assessment of Cognitive Dysfunction in Major Depressive Disorder: A 16-Week Prospective Case-Control Study
(AVES, 2021) Poyraz Çökmüş F.; Murat Özkan H.; Sücüllüoğlu-Dikici D.; Aşçibaşi K.; Alçi D.; Altunsoy N.; Kuru E.; Yüzeren S.; Aydemir Ö.
Objective: Cognitive dysfunction is one of the core components of major depressive disorder (MDD). It is estimated that two-thirds of patients diagnosed with MDD have cognitive deficits. Cognitive symptoms are pervasive and affect functioning in several domains. This 16-week prospective case-control study aimed to assess the change of mood and cognitive symptoms during treatment. Materials and Methods: Ninety-eight patients with MDD and 113 healthy controls (HCs) participated in the study. The MDD group was evaluated 6 times (baseline, 2nd, 4th, 8th, 12th, and 16th weeks). For mood symptoms, the Montgomery-Asberg Depression Rating Scale was used, and for neurocognitive functions, the Perceived Deficits Questionnaire-Depression was used, and the Digit Symbol Substitution Test was administered to both groups. Results: At baseline, compared with the HCs, the neurocognitive function of patients with MDD was worse. From the 8th to the 16th week assessments, in both neurocognitive tests, the cognitive functions of patients with MDD had improved. Despite this improvement and the patients achieving remission, the patients’ cognitive performance did not improve to the level of the HC group at the 16th week. Conclusion: Our longitudinal research revealed that even though mood symptoms decreased and patients with depression did achieve symptomatic remission, their cognitive deficits perpetuated. © 2020, AVES. All rights reserved.
Evaluation of microRNA expression levels during the craving period of patients diagnosed with severe alcohol use disorder
(Taylor and Francis Ltd., 2024) Aşçibaşi K.; Deveci A.; Özyılmaz B.; Erdoğan K.M.; Çakıroğlu E.
Background: The aim of this study is to compare the serum MicroRNA (miRNA) expression levels on the first day of hospitalization and at the end of the first month of treatment in patients with alcohol use disorder and severe craving symptoms. Through the obtained data, biological agents targeting microRNA for alcohol craving may be developed. Methods: The volunteer group consists of four patients diagnosed with severe alcohol use disorder. Sociodemographic and Clinical Information Form, DSM-5 Structured Clinical Interview-Clinical Version (SCID-5-CV), Penn Alcohol Craving Scale (PACS) were used as clinical assessment tools. Peripheral blood samples were obtained at the time of application and on the 30th day. miRNA isolation was performed. The expression levels of 2578 different mature human miRNAs were measured. Results: The miRNAs showing statistically significant differences in peripheral blood samples taken on the 1st and 30th days from alcohol users are as follows: miR-19a-3p, miR-6849-5p, miR-6726-5p, miR-6848-5p, miR-186-5p, miR-6889-5p, miR-933, miR-370-3p, miR-5739, miR-103a-2-5p, miR-6860, miR-1254, miR-1260a, miR-3921, miR-127-3p, miR-8064, miR-6870-5p, miR-4688 Conclusions: A significant difference was found between the 1st and 30th days in 18 of 2578 miRNAs scanned. It is aimed to investigate these 18 miRNAs in larger sample groups during the alcohol craving period. © 2023 Taylor & Francis Group, LLC.

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