Browsing by Author "Akgül Ö."
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Item Turkish compliance and adaptation of EULAR 2013 recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: Expert opinion of TLAR(Turkish League Against Rheumatism (TLAR), 2015) Ataman Ş.; Sari Sürmeli Z.; Sunar İ.; Özdemirel E.; Akinci A.; Bodur H.; Akgül Ö.; Altan L.; Altay Z.; Ayhan F.; Birtane M.; Soy Buğdayci D.; Çapkin E.; Cerrahoğlu L.; Duruöz M.T.; Günaydin R.; Günendi Z.; Gürer G.; Bal A.; Kaçar C.; Kaptanoğlu E.; Kaya T.; Kocabaş H.; Kotevoğlu N.; Nas K.; Rezvani A.; Şen N.; Şendur Ö.F.; Yalçin P.Objectives: This study aims to report Turkish League Against Rheumatism’s assessment on the compliance of European League Against Rheumatism 2013 treatment recommendations for rheumatoid arthritis with practices in Turkish rheumatology clinics and adaptations for Turkey. Materials and methods: Members of Turkish League Against Rheumatism and one rheumatoid arthritis patient voted for the 2013 recommendations of the European League Against Rheumatism for treatment of rheumatoid arthritis in two sessions. An item was changed and voted again only if at least 70% of participants wanted a change. Strength of recommendations was calculated for the items. Strength of recommendations for the changed items in the first and second voting rounds was compared by Wilcoxon signed-rank test. In case of significant difference, the item with higher strength of recommendation was accepted. In case of no difference, the changed item was selected. Results: Three overarching principles and fourteen recommendations were assessed among which the three overarching principles were changed emphasizing the importance of physiatrists as well as rheumatologists for taking care of the patients. Third item was changed by adding composite indices for assessing disease activity. In the ninth recommendation, rituximab was suggested as a first line drug independent of situations like latent tuberculosis or lymphoma, etc. In the 11th recommendation, unlike European League Against Rheumatism, our committee did not suggest any thought about tofacitinib, as then it had not been approved in Turkey. Remaining principles were accepted as the same. Conclusion: Expert opinion of Turkish League Against Rheumatism for treatment of rheumatoid arthritis patients was formed for practices in Turkish clinics. © 2015 Turkish League Against Rheumatism. All rights reserved.Item Ankle pain in hereditary multiple exostoses: A case report(Springer Verlag, 2015) Cerrahoğlu L.; Ulusoy A.; Akgül Ö.[No abstract available]Item Acute Pseudogout arthritis in a patient using diuretics(Turkish League Against Rheumatism (TLAR), 2016) Akkoç F.; Tikiz C.; Akgül Ö.[No abstract available]Item A rare cause for a gluteal pain in adults: Tuber ischium avulsion fracture; [Erişkinlerde nadir görülen bir gluteal ağrı nedeni: Tuber iskium avülsiyon kırığı](Turkish Society of Physical Medicine and Rehabilitation, 2016) Tıkız C.; Örgüç Ş.; Ulusoy A.; Akgül Ö.Tuber ischium avulsion fracture is a rare injury, of which the diagnosis is often missed or delayed. It usually occurs as a result of hamstring muscle contraction in adolescent athletes. Herein, we report a tuber ischium avulsion fracture developed in a 28-year-old male patient, who was admitted with the complaint of pain in the gluteal area after inguinal hernia surgery. © Telif Hakkı 2016 Türkiye Fiziksel Tıp ve Rehabilitasyon Derneği.Item Management of psoriatic arthritis: Turkish League Against Rheumatism (TLAR) expert opinions(Turkish League Against Rheumatism (TLAR), 2018) Nas K.; Kiliç E.; Çevik R.; Bodur H.; Ataman Ş.; Ayhan F.; Akgül Ö.; Akinci A.; Altay Z.; Çapkın E.; Dağli A.Z.; Duruöz T.; Gürer G.; Göğüş F.; Garip Y.; Kaçar C.; Kamanli A.; Kaptanoğlu E.; Kaya T.; Kocabaş H.; Özdemirel E.A.; Özel S.; Sezer İ.; Sunar İ.; Yilmaz G.Objectives: This study aims to establish the first national treatment recommendations by the Turkish League Against Rheumatism (TLAR) for psoriatic arthritis (PsA) based on the current evidence. Materials and methods: A systematic literature review was performed regarding the management of PsA. The TLAR expert committee consisted of 13 rheumatologists and 12 physical medicine and rehabilitation specialists experienced in the treatment and care of patients with PsA from 22 centers. The TLAR recommendations were built on those of European League Against Rheumatism (EULAR) 2015. Levels of evidence and agreement were determined. Results: Recommendations included five overarching principles and 13 recommendations covering therapies for PsA, particularly focusing on musculoskeletal involvement. Level of agreement was greater than eight for each item. Conclusion: This is the first paper that summarizes the recommendations of TLAR as regards the treatment of PsA. We believe that this paper provides Turkish physicians dealing with PsA patients a practical guide in their routine clinical practice. © 2018 Turkish League Against Rheumatism. All rights reserved.Item Turkish league against rheumatism (TLAR) recommendations for the pharmacological management of rheumatoid arthritis: 2018 update under guidance of current recommendations(Turkish League Against Rheumatism (TLAR), 2018) Ataman Ş.; Sunar İ.; Yilmaz G.; Bodur H.; Nas K.; Ayhan F.F.; Akgül Ö.; Akinci A.; Altay Z.; Birtane M.; SOY Buğdayci D.; Çapkin E.; Çevik R.; Garİp Çimen Y.; Duruöz M.T.; Elhan A.H.; Gürer G.; Kaçar C.; Kamanli A.; Kaptanoğlu E.; Kaya T.; Kocabaş H.; Kuru Ö.; Alkan Melikoğlu M.; Özel S.; Rezvani A.; Sezer İ.; Yurdakul F.G.Objectives: This study aims to report the assessment of the Turkish League Against Rheumatism (TLAR) expert panel on the compliance and adaptation of the European League Against Rheumatism (EULAR) 2016 recommendations for the management of rheumatoid arthritis (RA) in Turkey. Patients and methods: The EULAR 2016 recommendations for the treatment of RA were voted by 27 specialists experienced in this field with regard to participation rate for each recommendation and significance of items. Afterwards, each recommendation was brought forward for discussion and any alteration gaining ≥70% approval was accepted. Also, Turkish version of each item was rearranged. Last version of the recommendations was then revoted to determine the level of agreement. Levels of agreement of the two voting rounds were compared with Wilcoxon signed-rank test. In case of significant difference, the item with higher level of agreement was accepted. In case of no difference, the changed item was selected. Results: Four overarching principles and 12 recommendations were assessed among which three overarching principles and one recommendation were changed. The changed overarching principles emphasized the importance of physical medicine and rehabilitation specialists as well as rheumatologists for the care of RA patients in Turkey. An alteration was made in the eighth recommendation on treatment of active RA patients with unfavorable prognostic indicators after failure of three conventional disease modifying anti-rheumatic drugs. Remaining principles were accepted as the same although some alterations were suggested but could not find adequate support to reach significance. Conclusion: Expert opinion of the TLAR for the treatment of RA was composed for practices in Turkish rheumatology and/or physical medicine and rehabilitation clinics. © 2018 Turkish League Against Rheumatism. All rights reserved.Item Turkish league against rheumatism consensus report: Recommendations for management of axial spondyloarthritis(Turkish League Against Rheumatism (TLAR), 2018) Bodur H.; Yurdakul F.G.; Ataman Ş.; Garıp Y.; Nas K.; Ayhan F.F.; Akgül Ö.; Akinci A.; Altay Z.; Birtane M.; Soy Buğdayci D.; Çapkin E.; Çevık R.; Duruöz T.; Gürer G.; Kaçar C.; Kamanli A.; Kaptanoğlu E.; Kaya T.; Kocabaş H.; Kuru Ö.; Melikoğlu M.A.; Özdemırel E.; Özel S.; Rezvani A.; Sezer İ.; Sunar İ.; Yilmaz G.Objectives: This study aims to update 2011 Turkish League Against Rheumatism SpondyloArthritis Recommendations, and to compose a national expert opinion on management of axial spondyloArthritis under guidance of current guidelines, and implantation and dissemination of these international guidelines into our clinical practice. Materials and methods: A scientific committee of 28 experts consisting of 14 rheumatologists and 14 physical medicine and rehabilitation specialists (one of them also has an immunology PhD) was formed. The recommendations, systematic reviews, and meta-analyses including pharmacologic and non-pharmacologic treatment were scrutinized paying special attention with convenient key words. The draft of Turkish League Against Rheumatism opinion whose roof consisted of international treatment recommendations, particularly the Assessment of SpondyloArthritis International Society/European League Against Rheumatism recommendations was composed. Assessment of level of agreement with opinions by task force members was established through the Delphi technique. Voting using a numerical rating scale assessed the strength of each recommendation. Results: Panel compromised on five basic principles and 13 recommendations including pharmacological and nonpharmacological methods. All of the recommendations had adequate strength. Conclusion: Turkish League Against Rheumatism expert opinion for the management of axial spondyloArthritis was developed based on scientific evidence. These recommendations will be updated regularly in accordance with current developments. © 2018 Turkish League Against Rheumatism. All rights reserved.Item Low levels of pro-resolving lipid mediators lipoxin-A4, resolvin-D1 and resolvin-E1 in patients with rheumatoid arthritis(Elsevier B.V., 2020) Özgül Özdemir R.B.; Soysal Gündüz Ö.; Özdemir A.T.; Akgül Ö.Rheumatoid arthritis (RA) is a disease in which joint inflammation is at the forefront but the whole body is affected, and prevention of inflammation is the main treatment approach. Lipoxins (LXs) and resolvins (Rvs) are critical molecules in the resolution of inflammation. In this study, we aimed to investigate the role of LXs and Rvs in the RA pathogenesis. To this end, we measured the LXA 4, RvD 1, RvE 1 levels, and inflammatory cytokines and chemokines IL-6, IL-8, IL-10, IL-17a, IL-22 and MCP-1 in patients with RA and healthy individuals. We found that the LXA4, RvD1, RvE1 levels of the active RA cases were significantly lower than in remission RA and healthy individuals, but the levels of inflammatory cytokines and chemokines were significantly higher. The decreases in LXs and Rvs were independent of disease activity, suggesting that there might be an impairment of LX and Rvs synthesis or catabolism in patients with RA. © 2020 European Federation of Immunological SocietiesItem Validation of the turkish form of short form-12 health survey version 2 (Sf-12v2)(Turkish League Against Rheumatism (TLAR), 2021) Gündüz Ö.S.; Mutlu S.; Baslı A.A.; Gül C.; Akgül Ö.; Yılmaz E.; Aydemir Ö.Objectives: In this present study, we aimed to perform the reliability and validity analyses of the Turkish Form of Short Form-12 version 2 (SF-12v2) in different groups of patients. Patients and methods: After the permission for the validation study of the Turkish Form, Optum provided the authors the validly translated Turkish Form of SF-12v2. The study was carried out in rheumatological, psychiatric, and surgical wards of Manisa Celal Bayar University Hafsa Sultan Training and Research Center between September 2019 and June 2020. Taking possible dropouts into consideration, a total of 136 patients (67 males, 69 females; mean age: 43.5±14.4 years; range 19 to 82 years) constituted the study group. In addition to SF-12v2, for concurrent validity, Nottingham Health Profile (NHP) was used as the comparator instrument. Results: In internal consistency, for the physical component summary score, the Cronbach alpha coefficient was 0.80, and item-total score correlation coefficients were between 0.32 and 0.73. The Cronbach alpha coefficient of the mental component summary score was found to be 0.88 where the item-total correlation coefficients varied between 0.60 and 0.78. Exploratory factor analysis revealed a two-factor solution, representing mental and physical components. For criterion validity, convergent and discriminant validity analyses were performed using NHP with SF-12v2, and domains of SF-12v2 correlated well with the domains of NHP accordingly. In criterion validity, the psychiatric group had the lowest mean score in mental health, vitality, social functioning and role difficulties due to emotional problems, whereas the surgical group had the lowest mean score in bodily pain, role difficulties due to physical problems, and physical functioning. Conclusion: Our study results show that the Turkish form of SF-12v2 is valid and reliable both in clinical practice and clinical trials. © 2021 Turkish League Against Rheumatism. All rights reserved.Item Real-life data on the comorbidities in spondyloarthritis from our multicenter nationwide registry: BioStar(Turkish League Against Rheumatism (TLAR), 2023) Çay H.F.; Melikoğlu M.A.; Yurdakul F.G.; Bodur H.; Ataman Ş.; Çapkın E.; Gürer G.; Sezer İ.; Duruöz M.T.; Rezvani A.; Yağcı İ.; Göğüş F.; Kamanli A.; Çevik R.; Akgül Ö.Objectives: Considering that the comorbid situations during the management of Spondyloarthritis (SpA) have been underlined in several recommendations, the main objective of this study was to evaluate the comorbid conditions of Turkish patients with SpA. Patients and methods: This cross-sectional observational study was conducted with 1,242 SpA patients (844 males, 398 females; mean age: 43.9±11.0 years; range, 19 to 81 years) diagnosed according to the modified New York criteria for ankylosing spondylitis or the Assessment of SpondyloArthritis International Society (ASAS) criteria. The patient data were collected from the Biologic and targeted Synthetic antirheumatic drugs Registry (BioStar) between February 1, 2019, and December 29, 2020. Clinical and demographic data, including, age, sex, disease duration, body mass index (BMI), pain, patient’s global assessment, physician’s global assessment, Bath Ankylosing Spondylitis Disease Activity Index, Ankylosing Spondylitis Disease Activity Score, Bath Ankylosing Spondylitis Functional Index, Bath Ankylosing Spondylitis Metrology Index, and Maastricht Enthesitis Score, were recorded. Comorbid conditions were recorded by filling out a questionnaire according to the clinical history or medical records. Charlson Comorbidity Index and Rheumatic Disease Comorbidity Index scores were calculated from the gathered comorbidity information. Results: Nine hundred thirteen patients had radiographic axial SpA, 153 had nonradiographic axial SpA, and 176 had peripheral SpA. The most common comorbidities were hypertension (HT) (n=167, 13.4%), diabetes mellitus (DM) (n=83, 6.7%), thyroid disorders (n=64, 5.6%), and depression (n=61, 4.9%). The comorbidities and the calculated comorbidity indices were significantly higher in females, in those with a BMI >25 kg/m2, and those over 60 years of age. No relationship was found between smoking and alcohol use and comorbidities. A significantly higher prevalence of HT and DM in peripheral SpA patients and a lower prevalence of thyroid disorders in radiographic axial SpA patients were observed. Conclusion: The most commonly reported comorbidities were HT, DM, thyroid disorders, and depression in SpA patients according to the BioStar database. The frequency of comorbidities and composite comorbidity scores were higher among females, older (>60 years) patients, and overweight (BMI >25 kg/m2) patients. © 2023 Turkish League Against Rheumatism. All rights reserved.Item Patient Presenting with Hemoptysis: A Case of Hughes-Stovin Syndrome; [Hemoptizi ile Başvuran Hasta, Hughes-Stovin Sendromlu Bir Olgu](Galenos Publishing House, 2023) Alptürker K.A.; Akgül Ö.Hughes-Stovin syndrome (HSS) is a very rare autoimmune clinical disorder that has been described as the presence of thrombophlebitis and multiple aneurysms in pulmonary and/or bronchial arteries. The pathogenesis is still unknown, but this syndrome is often thought of as a manifestation of Behçet disease. Herein, we describe a 59-year-old male patient who was admitted to massive hemoptysis. HSS was diagnosed on the basis of imaging pulmonary artery aneurysms and a history of lower extremity thrombosis. It differs in terms of the occurrence of this rare syndrome in an elderly patient. In this syndrome, which has a high mortality, the results are satisfactory when the treatment is started with a rapid diagnosis. ©2023 by the Turkish Osteoporosis Society / Turkish Journal of Osteoporosis published by Galenos Publishing House. Licensed by CC BY-NC-ND.Item Prevalence of cardiovascular diseases and traditional cardiovascular risk factors in patients with rheumatoid arthritis: a real-life evidence from BioSTAR nationwide registry(Springer Science and Business Media Deutschland GmbH, 2024) Duruöz M.T.; Ataman Ş.; Bodur H.; Çay H.F.; Melikoğlu M.A.; Akgül Ö.; Çapkın E.; Gürer G.; Çevik R.; Göğüş F.N.; Kamanlı A.; Yurdakul F.G.; Yağcı I.; Rezvani A.; Altan L.Patients with rheumatoid arthritis (RA) have increased morbidity and mortality due to cardiovascular (CV) comorbidities. The association of CV diseases (CVD) and traditional CV risk factors has been debated, depending on patient and RA characteristics. This study aimed to find the prevalence of CVD and CV risk factors in patients with RA. A multi-center cross-sectional study was performed on RA patients using the BioSTAR (Biological and Targeted Synthetic Disease-Modifying Antirheumatic Drugs Registry) in September 2022. Socio-demographic, clinical, and follow-up data were collected. Myocardial infarction, ischemic heart disease, peripheral vascular disorders, congestive heart failure, ischemic stroke, and transient ischemic attack were regarded as major adverse cardiovascular events (MACEs). CVD was defined as the presence of at least one clinical situation of MACE. Group 1 and Group 2 included patients with and without CVD. Prevalence rates of CVD and traditional CV risk factors were the primary outcomes. Secondary outcomes were the differences in the clinical characteristics between patients with and without CVD. An analysis of 724 patients with a mean age of 55.1 ± 12.8 years diagnosed with RA was conducted. There was a female preponderance (79.6%). The prevalence rate of CVD was 4.6% (n = 33). The frequencies of the diseases in the MACE category were ischemic heart disease in 27, congestive heart failure in five, peripheral vascular disorders in three, and cerebrovascular events in three patients. The patients with CVD (Group 1) were significantly male, older, and had higher BMI (p = 0.027, p < 0.001, and p = 0.041). Obesity (33.4%) and hypertension (27.2%) were the two CV risk factors most frequently. Male sex (HR = 7.818, 95% CI 3.030–20.173, p < 0.001) and hypertension (HR = 4.570, 95% CI 1.567–13.328, p = 0.005) were the independent risk factors for CVD. The prevalence of CVD in RA patients was 4.6%. Some common risk factors for CVD in the general population, including male sex, older age, and hypertension, were evident in RA patients. Male sex and hypertension were the independent risk factors for developing CVD in patients with RA. © 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.Item Cross-sectional analysis of cardiovascular disease and risk factors in patients with spondyloarthritis: a real-life evidence from biostar nationwide registry(Springer Science and Business Media Deutschland GmbH, 2024) Duruöz M.T.; Bodur H.; Ataman Ş.; Gürer G.; Akgül Ö.; Çay H.F.; Çapkın E.; Sezer I.; Rezvani A.; Melikoğlu M.A.; Yağcı I.; Yurdakul F.G.; Göğüş F.N.; Kamanlı A.; Çevik R.; Altan L.The association between spondyloarthritis and cardiovascular (CV) diseases is complex with variable outcomes. This study aimed to assess the prevalence rates of CV diseases and to analyze the impact of CV risk factors on CV disease in patients with spondyloarthritis. A multi-center cross-sectional study using the BioSTAR (Biological and Targeted Synthetic Disease-Modifying Antirheumatic Drugs Registry) database was performed on patients with spondyloarthritis. Socio-demographic, laboratory, and clinical data were collected. Patients with and without major adverse cardiovascular events (MACE) were grouped as Group 1 and Group 2. The primary outcome was the overall group’s prevalence rates of CV disease and CV risk factors. The secondary outcome was the difference in socio-demographic and clinical characteristics between the groups and predictive risk factors for CV disease. There were 1457 patients with a mean age of 45.7 ± 10.9 years. The prevalence rate for CV disease was 3% (n = 44). The distribution of these diseases was coronary artery disease (n = 42), congestive heart failure (n = 4), peripheral vascular disorders (n = 6), and cerebrovascular events (n = 4). Patients in Group 1 were significantly male (p = 0.014) and older than those in Group 2 (p < 0.001). There were significantly more patients with hypertension, diabetes mellitus, chronic renal failure, dyslipidemia, and malignancy in Group 1 than in Group 2 (p < 0.05). Smoking (36.7%), obesity (24.4%), and hypertension (13.8%) were the most prevalent traditional CV risk factors. Hypertension (HR = 3.147, 95% CI 1.461–6.778, p = 0.003), dyslipidemia (HR = 3.476, 95% CI 1.631–7.406, p = 0.001), and cancer history (HR = 5.852, 95% CI 1.189–28.810, p = 0.030) were the independent predictors for CV disease. A multi-center cross-sectional study using the BioSTAR (Biological and Targeted Synthetic Disease-Modifying Antirheumatic Drugs Registry) database was performed on patients with spondyloarthritis. Socio-demographic, laboratory, and clinical data were collected. Patients with and without major adverse cardiovascular events (MACE) were grouped as Group 1 and Group 2. The primary outcome was the overall group’s prevalence rates of CV disease and CV risk factors. The secondary outcome was the difference in socio-demographic and clinical characteristics between the groups and predictive risk factors for CV disease. There were 1457 patients with a mean age of 45.7 ± 10.9 years. The prevalence rate for CV disease was 3% (n = 44). The distribution of these diseases was coronary artery disease (n = 42), congestive heart failure (n = 4), peripheral vascular disorders (n = 6), and cerebrovascular events (n = 4). Patients in Group 1 were significantly male (p = 0.014) and older than those in Group 2 (p < 0.001). There were significantly more patients with hypertension, diabetes mellitus, chronic renal failure, dyslipidemia, and malignancy in Group 1 than in Group 2 (p < 0.05). Smoking (36.7%), obesity (24.4%), and hypertension (13.8%) were the most prevalent traditional CV risk factors. Hypertension (HR = 3.147, 95% CI 1.461–6.778, p = 0.003), dyslipidemia (HR = 3.476, 95% CI 1.631–7.406, p = 0.001), and cancer history (HR = 5.852, 95% CI 1.189–28.810, p = 0.030) were the independent predictors for CV disease. The prevalence rate of CV disease was 3.0% in patients with spondyloarthritis. Hypertension, dyslipidemia, and cancer history were the independent CV risk factors for CV disease in patients with spondyloarthritis. © The Author(s) 2024.Item Arthritis induced by dupilumab treatment: A case report and literature review(Amaltea Medical Publishing House, 2024) Bıcılıoğlu C.; Onağ E.; Akgül Ö.Dupilumab is a human monoclonal IgG4 antibody targeting the interleukin-4 receptor alpha chain (IL-4Rα). It effectively inhibits the signaling pathways of both interleukin-4 (IL-4) and interleukin-13 (IL-13) and has been extensively employed in managing conditions such as atopic dermatitis, asthma, allergic rhinitis, and other allergic disorders. Despite numerous studies affirming its safety profile, suppression of IL-4 and IL-13 has been linked to an increased dominance of interleukin-17 (IL-17), which can lead to adverse effects resembling those seen in psoriatic arthritis and spondyloarthropathy-like symptoms. Through a case study of a patient receiving dupilumab for prurigo nodularis, this paper seeks to shed light on the potential inflammatory disease-like side effects associated with this treatment. Specifically, we explore manifestations such as enthesitis/arthritis, psoriasis, uveitis, inflammatory bowel disease, lupus erythematosus, and vasculitis, urging vigilance among rheumatologists and dermatologists. © 2024, Amaltea Medical Publishing House. All rights reserved.Item Pandemic of the century: COVID-19 in inflammatory rheumatic diseases of a national cohort with 3,532 patients(Turkish League Against Rheumatism (TLAR), 2024) Yurdakul F.; Bodur H.; Cengiz A.K.; Durmaz Y.; Duruöz M.T.; Kaya T.; Ketenci S.; Cüzdan N.; Güler T.; Günendi Z.; Sarıkaya S.; Çapkın E.; Önder M.E.; Melikoğlu M.A.; Güzel R.; Şen N.; Ayna A.B.; Akgül Ö.; Eser E.; Ataman Ş.Objectives: This study aimed to assess the clinical outcomes and risk factors for severe coronavirus disease 2019 (COVID-19) in patients with inflammatory rheumatic disease (IRD) of a national cohort. Patients and methods: The multicenter cross-sectional study was carried out between July 15, 2020, and February 28, 2021. Data collection was provided from a national network database system, and 3,532 IRD patients (2,359 males, 1,173 females; mean age: 48.7±13.9 years; range; 18 to 90 years) were analyzed. Demographics, clinics about rheumatic disease, comorbidities, smoking status, being infected with COVID-19, and the course of the infection were questioned by rheumatology specialists. Results: One hundred seventeen patients were infected with COVID-19, the hospitalization rate due to COVID-19 was 58.9%, and the mortality rate was 1.7%. There was no difference between the COVID-19 positive and negative groups in terms of rheumatic disease activities and receiving drugs. It was observed that patients with COVID-19 had worse compliance with isolation rules, and bacillus Calmette-Guérin (BCG) vaccination was less common. The mean age and the rate of smoking of hospitalized COVID-19 patients were higher than those without hospitalization. Conclusion: In this cohort, in which real-life data were analyzed, COVID-19 rates in IRD patients were similar to the general population for the same period. Compliance with the isolation rules and BCG vaccination attracted attention as components that reduce the risk of COVID-19 infection. The risk factors for hospitalization were older age and smoking. © 2024, Turkish League Against Rheumatism (TLAR). All rights reserved.