Browsing by Author "Akin, F"

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    Retinal abnormalities and their relationship with social cognition in patients with schizophrenia and their healthy siblings
    Akin, F; Danaci, AE; Kayikcioglu, RO; Tasci, MY
    Objective: This study aimed to investigate retinal abnormalities and their relationship with social cognitive function, and to assess whether retinal changes could be observed in the healthy siblings of patients with schizophrenia in a similar manner, suggesting their potential as an endophenotype. Method: The study included 28 patients with schizophrenia, 28 of their siblings, and 28 healthy control subjects. Social cognition tests were administered, and measurements of the retinal nerve fiber layers (RNFL), ganglion cell layer plus inner plexiform layer (GCL+IPL), and cup volumes were obtained using optical coherence tomography (OCT). Results: Analyses revealed no differences between the groups in RNFL thickness. The cup volume was significantly larger in both eyes of the patient group compared to the control group. The mean thickness of the GCL+IPL in the left eye was significantly lower in the patient group compared to the healthy control group, with a similar difference also observed between the siblings of patients and the control group. A statistically significant difference was found among all groups in the total scores of social cognition tests. A weak correlation was identified between retinal layer thicknesses and social cognition test scores in both the patient and sibling groups. Conclusion: These findings suggest that GCL+IPL thickness can be a useful endophenotype for the early diagnosis of schizophrenia. While retinal changes do not predict cognitive symptoms in patients with schizophrenia, they may play an important role in identifying high-risk groups.
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    Disease burden and associated factors in caregivers of patients with obsessive-compulsive disorder
    Suculluoglu-Dikici, D; Cokmus, FP; Akin, F; Eser, E; Demet, MM
    Objective: Obsessive-compulsive disorder (OCD) is one of the leading causes of disability and poor quality of life, with impairment in many areas. It can also adversely affect family members and friends that the person lives with, and this results in a burden. We aimed to evaluate the disease burden in caregivers of patients with OCD and the factors that negatively affect caregiver burden. Method: The study population consisted of 94 patients with OCD and their caregivers. The Yale-Brown Obsessive-Compulsive Scale (YBOCS), the Hamilton Depression Rating Scale, and the World Health Organization Quality of Life Questionnaire Brief Form were filled out by the patients, and the Burden Assessment Scale (BAS) by the caregivers. Results: Longer duration of treatment, higher YBOCS obsession and compulsion scores of the patients, and lower environmental quality of life dimension scores of the patients were found to increase the BAS scores of the caregivers. Additionally, these variables were found to be significant predictors for disease burden (BAS score) (p<0.05). Conclusion: Our study revealed that many variables affect burden, even in caregivers who have no extra burden (who has no disease to cause a burden). Caregivers of patients with OCD should be included in the behavioral and pharmacologic treatment process for the benefit of both the OCD treatment management and the protection of family health.
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    A snapshot of pediatric inpatients and outpatients with COVID-19: a point prevalence study from Turkey
    Yilmaz, D; Üstündag, G; Büyükçam, A; Sali, E; Çelik, Ü; Avcu, G; Belet, N; Taskin, EÇ; Demir, SÖ; Birbilen, AZ; Kiliç, Ö; Akcan, ÖM; Yilmaz, AT; Kocabas, BA; Hatipoglu, N; Karbuz, A; Çakir, D; Sütçü, M; Aygün, FD; Çelik, T; Sen, SB; Dalgiç, N; Ümit, Z; Kara, SS; Öncel, EK; Bolat, A; Çil, MK; Turan, C; Guzin, AÇ; Topal, S; Besli, GE; Dogan, G; Sahin, S; Akin, F; Bildirici, Y; Dayar, GT; Sari, EE; Isançli, DK; Kara, M; Önal, P; Aylaç, H; Lüleci, D; Yasar, B; Dede, E; Çaglar, A; Akova, S; Turgut, EA; Özkaya, PY; Gülmez, TK; Ulusoy, E; Duyu, M; Kara, Y; Çeliktas, H; Tekeli, O; Çaglar, F; Gül, D; Cebeci, SO; Battal, F; Bal, A; Aygün, E; Uysalol, M; Arslan, G; Özkavakli, A; Kizil, MC; Yazar, A; Aygün, F; Somer, A; Kuyucu, N; Dinleyici, EÇ; Kara, A
    This multi-center point prevalence study evaluated children who were diagnosed as having coronavirus disease 2019 (COVID19). On February 2nd, 2022, inpatients and outpatients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were included in the study from 12 cities and 24 centers in Turkey. Of 8605 patients on February 2nd, 2022, in participating centers, 706 (8.2%) had COVID-19. The median age of the 706 patients was 92.50 months, 53.4% were female, and 76.7% were inpatients. The three most common symptoms of the patients with COVID-19 were fever (56.6%), cough (41.3%), and fatigue (27.5%). The three most common underlying chronic diseases (UCDs) were asthma (3.4%), neurologic disorders (3.3%), and obesity (2.6%). The SARS-CoV-2-related pneumoniae rate was 10.7%. The COVID-19 vaccination rate was 12.5% in all patients. Among patients aged over 12 years with access to the vaccine given by the Republic of Turkey Ministry of Health, the vaccination rate was 38.7%. Patients with UCDs presented with dyspnea and pneumoniae more frequently than those without UCDs (p < 0.001 for both). The rates of fever, diarrhea, and pneumoniae were higher in patients without COVID-19 vaccinations (p = 0.001, p = 0.012, and p = 0.027). Conclusion: To lessen the effects of the disease, all eligible children should receive the COVID-19 vaccine. The illness may specifically endanger children with UCDs.