Browsing by Author "Akin, IB"

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    Evaluation of abdominal computed tomography findings in patients with COVID-19: a multicenter study
    Onur, MR; Özbay, Y; Idilman, I; Karaosmanoglu, AD; Ramadan, SU; Barlik, F; Aydin, S; Odaman, H; Altay, C; Akin, IB; Dicle, O; Appak, O; Gülpinar, B; Erden, A; Kula, S; Çoruh, AG; Öz, DK; Kul, M; Uzun, C; Karavas, E; Levent, A; Artas, H; Eryesil, H; Solmaz, O; Kaygusuz, TO; Farasat, M; Kale, AB; Düzgün, F; Pekindil, G; Apaydin, FD; Duce, MN; Balci, Y; Esen, K; Kahraman, AS; Karaca, L; Özdemir, ZM; Kahraman, B; Tosun, M; Nural, MS; Camlidag, I; Onar, MA; Balli, K; Güler, E; Harman, M; Elmas, NZ; Öztürk, C; Güngör, O; Herek, D; Yagci, AB; Erol, C; Seker, M; Islek, I; Can, Y; Aslan, S; Bilgili, MYK; Göncüoglu, A; Keles, H; Sarikaya, PZB; Bakir, B; Kartal, MGD; Durak, G; Oguzdogan, GY; Alper, F; Yalçin, A; Gürel, S; Alan, B; Gündogdu, E; Aydin, N; Cansu, A; Kus, CC; Tuncer, EO; Piskin, FC; Er, HC; Degirmenci, B; Özmen, MN; Kantarci, M; Karçaaltincaba, M
    PURPOSETo evaluate the frequency of abdominal computed tomography (CT) findings in patients with coronavirus disease-2019 (COVID-19) and interrogate the relationship between abdominal CT findings and patient demographic features, clinical findings, and laboratory test results as well as the CT atheroscle-rosis score in the abdominal aorta.METHODSThis study was designed as a multicenter retrospective study. The abdominal CT findings of 1.181 patients with positive abdominal symptoms from 26 tertiary medical centers with a positive polymerase chain-reaction test for severe acute respiratory syndrome coronavirus 2 were reviewed. The frequency of ischemic and non-ischemic CT findings as well as the association between CT findings, clinical features, and abdominal aortic calcific atherosclerosis score (AA-CAS) were recorded.RESULTSIschemic and non-ischemic abdominal CT findings were detected in 240 (20.3%) and 328 (27.7%) patients, respectively. In 147 patients (12.4%), intra-ab-dominal malignancy was present. The most frequent ischemic abdominal CT findings were bowel wall thickening (n = 120; 10.2%) and perivascular infil-tration (n = 40; 3.4%). As for non-ischemic findings, colitis (n = 91; 7.7%) and small bowel inflammation (n = 73; 6.2%) constituted the most frequent disease processes. The duration of hospital stay was found to be higher in patients with abdominal CT findings than in patients without any positive findings (13.8 & PLUSMN; 13 vs. 10.4 & PLUSMN; 12.8 days, P < 0.001). The frequency of abdominal CT findings was significantly higher in patients who did not survive the infection than in patients who were discharged after recovery (41.7% vs. 27.4%, P < 0.001). Increased AA-CAS was found to be associated with a higher risk of ischemic conditions in abdominal CT examinations.CONCLUSIONAbdominal symptoms in patients with COVID-19 are usually associated with positive CT findings. The presence of ischemic findings on CT correlates with poor COVID-19 outcomes. A high AA-CAS is associated with abdominal ischemic findings in patients with COVID-19.
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    Outcomes of high-risk breast lesions diagnosed using image-guided core needle biopsy: results from a multicenter retrospective study
    Oktay, A; Aslan, Ö; Taskin, F; Tunçbilek, N; Içten, SGE; Balci, P; Aribal, ME; Çelik, L; Örguç, IS; Demirkazik, FB; Gültekin, S; Aydin, AM; Durmaz, E; Kul, S; Binokay, F; Çetin, M; Emlik, GD; Akpinar, MG; Voyvoda, SNK; Polat, AV; Akin, IB; Yildiz, S; Poyraz, N; Özsoy, A; Öztekin, PS; Elverici, E; Bayrak, IK; Ikizceli, T; Dinç, F; Sezgin, G; Gülsen, G; Tunçbilek, I; Yalçin, SR; Çolakoglu, G; Aglamis, S; Yilmaz, R; Rona, G; Durhan, G; Güner, DC; Yabul, FÇ; Karabekmez, LG; Tutar, B; Göktas, M; Bugdayci, O; Suner, A; Özdemir, N
    PURPOSE The clinical management of high-risk lesions using image-guided biopsy is challenging. This study aimed to evaluate the rates at which such lesions were upgraded to malignancy and identify possible predictive factors for upgrading high-risk lesions. METHODS This retrospective multicenter analysis included 1.343 patients diagnosed with high-risk lesions using an image-guided core needle or vacuum-assisted biopsy (VAB). Only patients managed using an excisional biopsy or with at least one year of documented radiological follow-up were included. For each, the Breast Imaging Reporting and Data System (BI-RADS) category, number of samples, needle thickness, and lesion size were correlated with malignancy upgrade rates in different histologic subtypes. Pearson's chi-squared test, the Fisher-Freeman-Halton test, and Fisher's exact test were used for the sta-tistical analyses. RESULTS The overall upgrade rate was 20.6%, with the highest rates in the subtypes of intraductal papilloma (IP) with atypia (44.7%; 55/123), followed by atypical ductal hyperplasia (ADH) (38.4%; 144/375), lobular neoplasia (LN) (12.7%; 7/55), papilloma without atypia (9.4%; 58/611), flat epithelial atypia (FEA) (8.7%; 10/114), and radial scars (RSs) (4.6%; 3/65). There was a significant relationship between the upgrade rate and BI-RADS category, number of samples, and lesion size Lesion size was the most predictive factor for an upgrade in all subtypes.CONCLUSION ADH and atypical IP showed considerable upgrade rates to malignancy, requiring surgical excision. The LN, IP without atypia, pure FEA, and RS subtypes showed lower malignancy rates when the BI-RADS category was lower and in smaller lesions that had been adequately sampled using VAB. After being discussed in a multidisciplinary meeting, these cases could be managed with follow-up instead of excision.