Browsing by Author "Aksoy, F"

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    Lack of Association between the Glu298Asp Polymorphism of Endothelial Nitric Oxide Synthase and Slow Coronary Flow
    Yücel, H; Dogan, A; Türker, Y; Içli, A; Akçay, S; Ersoy, I; Aksoy, F; Sütçü, R
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    No Association between the Methyleletetrahydrofolate Reductase A1298C Variants and Atrial Fibrillation with Ischemic Stroke in Turkish Population
    Içli, A; Erten, N; Arslan, A; Yücel, H; Akçay, S; Yasar, E; Uysal, BA; Bas, HA; Aksoy, F; Sütçü, R
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    GENETIC POLYMORPHISMS OF THE HUMAN PLATELET ANTIGENS-1 IN ISOLE CORONARY ARTERY ECTASIA
    Içli, A; Altinbas, A; Türker, Y; Yücel, H; Akçay, S; Aksoy, F; Sütçü, R; Bas, HA
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    Production of waste tyre oil and experimental investigation on combustion, engine performance and exhaust emissions
    Uyumaz, A; Aydogan, B; Solmaz, H; Yilmaz, E; Hopa, DY; Bahtli, TA; Solmaz, Ö; Aksoy, F
    In this study, waste tyre was pyrolyzed at different conditions such as temperature, heating rate and inert purging gas (N-2) flow rate. Pyrolysis parameters were optimized. Optimum parameters were determined. The main objective of this study was to investigate combustion, performance and emissions of diesel and waste tyre oil fuel blend. Experimental investigation was performed in a single cylinder, direct injection, air cooled diesel engine at maximum engine torque speed of 2200 rpm and four different engine load including 3.75, 7.5, 11.25 and 15 Nm. The effects of waste tyre oil on combustion characteristics such as cylinder pressure, heat release rate, ignition delay (ID), combustion duration, engine performance were investigated. In-cylinder pressure and heat release rate increased with waste tyre oil fuel blend (W10) with the increase of engine load. In addition, ID was shortened with the increase of engine load for test fuels but it increased with the addition of waste tyre oil. Lower imep values were obtained because of the lower calorific value of waste tyre oil fuels. Maximum thermal efficiencies were determined as 28.27% and %25.12 with diesel and W10 respectively at 11.25 Nm engine load. When test results were examined, it was seen that waste tyre oil highly affected combustion characteristics, performance and emissions. (C) 2018 Energy Institute. Published by Elsevier Ltd. All rights reserved.
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    Increased Mean Platelet Volume in Hypertrophic Cardiomyopathy
    Icli, A; Aksoy, F; Dogan, A; Arslan, A; Akcay, S; Yücel, H; Ersoy, I; Gorgulu, O
    Thromboembolic events may be seen in patients with hypertrophic cardiomyopathy (HCM). We investigated the mean platelet volume (MPV), an indicator of platelet activation in patients with HCM. This study included 112 patients with HCM, in which 40 were patients with hypertrophic obstructive cardiomyopathy (HOCM), and 106 were control participants. The MPV was significantly higher in patients with HCM than in controls (9.1 +/- 0.3 vs 7.9 +/- 0.3 fL, P = .01). In the subgroup analyses, MPV was also higher in patients with HOCM compared to those with hypertrophic nonobstructive cardiomyopathy (HNCM; 9.3 +/- 0.3 vs 9.0 +/- 0.2 fL, P = .01). Similarly, patients with HNCM had higher MPV values than controls (9.0 +/- 0.2 vs 7.9 +/- 0.3 fL, P = .01). The MPV was significantly and positively correlated with left ventricular outflow tract (LVOT) obstruction (r = .42, P = .001) and septal thickness (r =.62, P = .001). In linear regression analysis, MPV was independently associated only with septal thickness (beta = .07, 95% confidence interval: 0.04-0.09, P = .001). The MPV can be elevated in patients with HCM regardless of the obstruction of LVOT and may be associated with the severity of septal thickness.
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    HUMAN PLATELET ALLOANTIGENS HPA-1 POLYMORPHISMS ASSOCIATED WITH CORONARY ARTERY DISEASE
    Içli, A; Altinbas, A; Türker, Y; Yücel, H; Aksoy, F; Ersoy, I; Akçay, S; Sütçü, R; Arslan, A
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    THE RELATIONSHIP BETWEEN ENDOTHELIAL NITRIC OXIDE SYNTHASE GENE POLYMORPHISM (T-786 C) AND ISOLE CORONARY ARTERY ECTASIA
    Içli, A; Altinbas, A; Türker, Y; Yücel, H; Akçay, S; Aksoy, F; Ersoy, I; Sütçü, R
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    Evaluation of the Apolipoprotein B R3500Q Gene Mutation in Nonvalvular Atrial Fibrillation with Ischemic Stroke in Turkish Population
    Icli, A; Erten, N; Sütcü, R; Akcay, S; Yasar, E; Yücel, H; Aksoy, F; Arslan, A
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    EVALUATION OF LYMPHOTOXIN-ALPHA C804A GENE POLYMORPHISMS IN PATIENTS WITH ISOLE CORONARY ARTERY ECTASIA
    Içli, A; Altinbas, A; Türker, Y; Akçay, S; Yücel, H; Aksoy, F; Sütçü, R; Uysal, BA
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    POLYMORPHISMS OF THE APOLIPOPROTEIN B GENE R3500Q IN PATIENTS WITH CORONARY ARTERY DISEASE
    Içli, A; Aksoy, F; Yücel, H; Akçay, S; Sütçü, R; Arslan, A; Adali, MK; Altinbas, A
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    Is Nurse Workforce Sufficient in Intensive Care Units in Turkey. Results of the Multicenter Karia Study
    Uyan, A; Durmus, G; Sezak, N; Pepe, F; Kaygusuz, T; Öztoprak, N; Özdemir, K; Aksoy, F; Erol, S; Koç, MM; Öncül, A; Çagan Aktas, S; Çaskurlu, H; Çelebi, G; Kandemir, O; Özger, S; Harman, R; Demiray, K; Ari, A; Alkan Çeviker, S; Esen Yildiz, I; Menekse, S; Senol, G; Sari, S; Dogan, M; Ugurlu, K; Arslan, M; Akdemir, I; Firat, P; Kürekçi, Y; Çaglayan, D; Uçar, M; Gözüküçük, R; Elmaslar Mert, HT; Alay, H; Erdogan, H; Demirel, A; Dogan, N; Koçak, F; Güven, E; Ünsal, G; Sipahi, H; Isikgöz Tasbakan, M; Arda, B; Ulusoy, S; Sipahi, OR
    Introduction: In this multicenter study, we analysed the magnitude of healthcare worker (HCW) [infection control practitioner (ICP), nurses and others] workforce in hospitals participated in the study. Materials and Methods: This study was performed in 41 hospitals (with intensive care units-ICU) located in 22 cities from seven regions of Turkey. We analysed the ICP workforce, nursing and auxiliary HCW (AHCW) workforce in ICUs, number of ICU beds and occupied beds in four different days [two of which were in summer during the vacation time (August 27 and 31, 2016) and two others in autumn (October 12 and 15, 2016)]. The Turkish Ministry of Health (TMOH) requires two patients per nurse in level 3 ICUs, three patients per nurse in level 2 ICUs and five patients per nurse in level 1 ICUs. There is no standardization for the number of AHCW in ICUs. Finally, one ICP per 150 hospital beds is required by TMOH. Results: The total number of ICUs, ICU beds and ICPs were 214, 2377 and 111, respectively in he 41 participated centers. The number ICPs was adequate only in 12 hospitals. The percentage of nurses whose working experience was <1 year, was; 19% in level 1 ICUs, 25% in level 2 ICUs and 24% in level 3 ICUs. The number of patients per nurse was mostly <5 in level 1 ICUs whereas the number of patients per nurse in level 3 ICUs was generally >2. The number of patients per other HCW was minimum 3.75 and maximum 4.89 on weekdays and on day shift while it was minimum 5.02 and maximum 7.7 on weekends or on night shift. When we compared the number of level 1, 2 and 3 ICUs with adequate nursing workforce vs inadequate nursing workforce, the p value was <0.0001 at all time points except summer weekend night shift (p=0.002). Conclusion: Our data suggest that ICP workforce is inadequate in Turkey. Besides, HCW workforce is inadequate and almost 1/4 of nurses are relatively inexperienced especially in level 3 ICUs. Turkish healthcare system should promptly make necessary arrangements for adequate HCW staffing.
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    Are Soap, Paper Towel and Alcohol-based Disinfectants Easily Accessible in Intensive Care Units in Turkey?: Results of the Phokai Study
    Uyan, A; Durmus, G; Sezak, N; Özdemir, B; Kaygusuz, T; Öztoprak, N; Özdemir, K; Aksoy, F; Özgültekin, A; Koç, MM; Öncül, A; Çagan Aktas, S; Isik, B; Çelebi, G; Evik, G; Özger, S; Harman, R; Dindar Demiray, EK; Özkören Çalik, S; Alkan Çeviker, S; Yildiz, IE; Isik, ME; Senol, G; Sari, S; Dogan, M; Ugurlu, K; Arslan, M; Akgül, F; Koç, F; Kürekçi, Y; Çaglayan, D; Uçar, M; Gözüküçük, R; Elmaslar Mert, HT; Alay, H; Erdogan, H; Demirel, A; Dogan, N; Koçak, F; Güven, E; Ünsal, G; Sipahi, H; Yamazhan, T; Arda, B; Ulusoy, S; Sipahi, OR
    Introduction: Hand hygiene is one of the most effective infection control measures to prevent the spread of healthcare-associated infections (HCAI). Water, soap, paper towel and hand disinfectant must be available and adequate in terms of effective hand hygiene. The adequacy of hand hygiene products or keeping water-soap and paper towel is still a problem for many developing countries like Turkey. In this multicenter study, we analyzed the adequacy in number and availability of hand hygiene products. Materials and Methods: This study was performed in all intensive care units (ICUs) of 41 hospitals (27 tertiary-care educational, 10 state and four private hospitals) from 22 cities located in seven geographical regions of Turkey. We analyzed water, soap, paper towel and alcohol-based hand disinfectant adequacy on four different days, two of which were in summer during the vacation time (August, 27th and 31st 2016) and two in autumn (October, 12th and 15th 2016). Results: The total number of ICUs and intensive care beds in 41 participating centers were 214 and 2357, respectively. Overall, there was no soap in 3-11% of sinks and no paper towel in 10-18% of sinks while there was no alcohol-based hand disinfectant in 1-4.7% of hand disinfectant units on the observation days. When we compared the number of sinks with soap and/or paper towel on weekdays vs. weekends, there was no significant difference in summer. However, on autumn weekdays, the number of sinks with soap and paper towel was significantly lower on weekend days (p<0.0001, p<0.0001) while the number of hand disinfectant units with alcohol-based disinfectant was significantly higher (p<0.0001). Conclusion: There should be adequate and accessible hand hygiene materials for effective hand hygiene. In this study, we found that soap and paper towels were inadequate on the observation days in 3-11% and 10-18% of units, respectively. Attention should be paid on soap and paper towel supply at weekends as well.
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    The Relationship between Endothelial Nitric Oxide Synthase Gene Polymorphism (G894T) and Isole Coronary Artery Ectasia
    Içli, A; Altinbas, A; Türker, Y; Yücel, H; Akçay, S; Sütçü, R; Aksoy, F; Arslan, A; Tayyar, S; Uysal, BA
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    The Beta-Fibrinogen 455 G/A Gene Polymorphism Associated with Coronary Artery Disease
    Içli, A; Altinbas, A; Türker, Y; Sütçü, R; Akçay, S; Yücel, H; Görgülü, Ö; Bas, HA; Aksoy, F; Uysal, BA
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    Beta Fibrinogen-455 G>A Gene Polymorphism in Coronary Artery Ectasia
    Içli, A; Altinbas, A; Yücel, H; Türker, Y; Akçay, S; Sütçü, R; Görgülü, Ö; Bas, HA; Aksoy, F
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    EVALUATION OF LYMPHOTOXIN-ALPHA C804A GENE POLYMORPHISMS IN PATIENTS WITH CORONARY HEART DISEASE
    Içli, A; Altinbas, A; Türker, Y; Yücel, H; Akçay, S; Sütçü, R; Arslan, A; Aksoy, F