Browsing by Author "Aksu, F"

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    The Relationship between Basal Ganglia Volume and Audiovisual Reaction Time in Turkish Elite Athletes
    Karabekir, S; Aksu, F; Gunay, E; Karabekir, NG
    Background: In this study involving young adult elite athletes and healthy sedentary individuals, volumetric analyses were performed on basal ganglia (BG) involved in the coordination of motor movements. Aims and Objectives: In a group of athletes with high coordination speed, potential relationship between BG volumes and audiovisual reaction time of acquired-trained hand movements was explored by examining whether these individuals had significant differences in terms of BG volumes. Materials and Methods: Nineteen elite athletes aged between 19 and 25 years (9 male and 10 female) and 20 sedentary subjects (10 male, 10 female) were included. Gender, age, height, weight, and body-mass index (BMI) were recorded. In each group, audiovisual reaction time and stereological basal ganglia volumes were assessed and statistically analyzed. Results: Elite athletes react more rapidly to auditory stimuli than visual stimuli. As compared to sedentary individuals, elite athletes exhibited significantly shorter visual reaction time and only numerically shorter (statistically insignificant) visual reaction time. Left BG volume was higher in both groups, compared to right side). Conclusion: Our data may contribute to the construction of a database of normal BG morphology and provide useful information for clinicians and athletes.
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    The effects of some K+ channel blockers on scopolamine- or electroconvulsive shock-induced amnesia in mice
    Inan, SY; Aksu, F; Baysal, F
    The effects of three K+ channel blockers, 4-aminopyridine, 3,4-diaminopyridine and apamin, on scopolamine- or electroconvulsive shock-induced amnesia were investigated in mice by using a one-trial step-down passive avoidance system. Scopolamine and electroconvulsive shuck reduced the retention latency of passive avoidance, which indicated the amnestic effect of these treatments. 4-Aminopyridine, 3,4-diaminopyridine and apamin injected immediately after the acquisition trial, reversed the amnestic effect of scopolamine or electroconvulsive shuck in a dose-dependent manner. None of the drugs or electroconvulsive shock treatment affected the rotarod or activity cage performance of the mice. These results indicate that K+ channel blockers may improve cognitive deficits when memory is impaired by a drug or any other manipulation. (C) 2000 Elsevier Science B.V. All rights reserved.