Browsing by Author "Akyil, FT"

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    Prognosis of hospitalized patients with community-acquired pneumonia
    Akyil, FT; Yalcinsoy, M; Hazar, A; Cilli, A; Celenk, B; Kilic, O; Sayiner, A; Kokturk, N; Coskun, AS; Filiz, A; Edis, EC
    Introduction: The long-term prognosis of patients with community-acquired pneumonia (CAP) has attracted increasing interest in recent years. The objective of the present study is to investigate the short and long-term outcomes in hospitalized patients with CAP and to identify the predictive factors associated with mortality. Patients and methods: The study was designed as a retrospective, multicenter, observational study. Hospitalized patients with CAP, as recorded in the pneumonia database of the Turkish Thoracic Society between 2011 and 2013, were included. Short-term mortality was defined as 30-day mortality and long-term mortality was assessed from those who survived 30 days. Predictive factors for short- and long-term mortality were analyzed. Results: The study included 785 patients, 68% of whom were male and the mean age was 67 +/- 16 (18-92). The median duration of follow-up was 61.2 +/- 11.8 (37-90) months. Thirty-day mortality was 9.2% and the median survival of patients surviving 30 days was 62.8 +/- 4.4 months. Multivariate analysis revealed that advanced age, the absence of fever, a higher Charlson comorbidity score, higher blood urea nitrogen (BUN)/albumin ratios and lower alanine aminotransferase (ALT) levels were all predictors of long-term mortality. Conclusion: Long-term mortality following hospitalization for CAP is high. Charlson score and lack of fever are potential indicators for decreased long-term survival. As novel parameters, baseline BUN/albumin ratios and ALT levels are significantly associated with late mortality. Further interventions and closer monitoring are necessary for such subgroups of patients. (C) 2017 Sociedade Portuguesa de Pneumologia. Published by Elsevier Espana, S.L.U.
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    Factors affecting short and long-term mortality after community-acquired pneumonia
    Akyil, FT; Hazar, A; Yalçinsoy, M; Çilli, A; Çelenk, B; Kilinç, O; Kilinç, Ö; Sayiner, A; Tasbakan, S; Köktürk, N; Coskun, AS; Havlucu, Y; Filiz, A; Edis, EÇ
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    Turkish Thoracic Society Early Career Members Task Force Group's Virtual Congress Notes: European Respiratory Society International Congress 2020
    Kizilirmak, D; Karadogan, D; Yildirim, H; Akyil, FT; Eyüboglu, TS; Emiralioglu, N; Sertçelik, ÜÖ; Günaydin, FE; Ataoglu, Ö; Oguz, MS; Çakmakci, S; Özçelik, N; Öncel, A; Firincioglulari, A; Kara, BY; Ömer, D; Karaoglanoglu, S; Cetin, N; Karakas, FG; Gurkan, CG; Marim, F; Önyilmaz, T; Yulug, DP; Öztürk, NAA; Güçlü, ÖA; Küsbeci, TÇ; Serifoglu, I; Arikan, H; Töreyin, ZN; Çelik, P; Akgün, M
    In this article, Early Career Task Force Group members of the Turkish Thoracic Society summarize the European Respiratory Society 2020 virtual congress. Current developments in the field of respiratory diseases were compiled with the addition of sessions specific to coronavirus disease 2019 this year. Almost all of the congress sessions were examined, and the important and striking results of the congress were highlighted. Congress sessions were attended by expert researchers, and the prominent messages of each session were highlighted in short summaries. They were then grouped under relevant titles and ranked in order of meaning and relation. It was finalized by a team of researchers.
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    COVID-19 Pandemic and the Global Perspective of Turkish Thoracic Society
    Köktürk, N; Itil, BO; Altinisik, G; Adigüzel, N; Akgün, M; Akyildiz, L; Altin, S; Arikan, H; Ates, G; Ay, P; Aykaç, N; Babayigit, C; Bostan, P; Cinel, G; Çalisir, HC; Çelik, P; Çetinkaya, PD; Dagli, E; Demir, AU; Demir, C; Dikensoy, Ö; Edis, EÇ; Elbek, O; Erdinç, M; Ergan, B; Eyüboglu, AFÖ; Gemicioglu, B; Göksel, T; Gülhan, E; Gültekin, Ö; Gürkan, CG; Gürgün, A; Havlucu, Y; Basoglu, OK; Karakurt, S; Karkurt, Z; Kilinç, O; Kocabas, A; Kul, S; Müsellim, B; Nayci, S; Özkan, M; Pinarer, Ö; Saltürk, C; Sandal, A; Sayiner, A; Sen, E; Simsek, GÖ; Karadag, BT; Akyil, FT; Töreyin, ZN; Uçan, ES; Küçük, FÇU; Varol, A; Yasin, Y; Yildiz, T; Yorgancioglu, AA; Bayram, H
    It has been more than 3 months now since the first case of COVID-19 was reported in Turkey. Globally, the number of confirmed cases and deaths reached 9,653,048 and 491,128 respectively, as reported by 216 countries by June 27, 2020. Turkey had 1,396 new cases, 194,511 total cases, and 5,065 deaths by the same date. From the first case until today, the Turkish Thoracic Society (TTS) has been very proactive in educating doctors, increasing public awareness, undertaking academic studies, and assisting with public health policies. In the present report, social, academic, and management perspectives of the pandemic are presented under appropriate subtitles. During this critical public health crisis, TTS has once again demonstrated its readiness and constructive stance by supporting public health, healthcare workers, and the environment. This review summarizes the perspective of TTS on each aspect of the COVID-19 pandemic and casts light on its contributions.
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    What We Learned about COVID-19 So Far? Notes from Underground
    Akyil, FT; Karadogan, D; Gürkan, CG; Yüksel, A; Arikan, H; Eyüboglu, TS; Emiralioglu, N; Gürsoy, TR; Serifoglu, I; Toreyin, ZN; Marim, F; Kara, BY; Özakinci, H; Develi, E; Çakmakci, S; Kusbeci, TC; Karcioglu, O; Gulhan, PY; Erçelik, M; Er, B; Ataoglu, Ö; Polat, D; Kaya, I; Önyilmaz, TA; Aydin, A; Kizilirmak, D; Er, AB; Kilinç, M; Günaydin, FE; Gürz, S; Karaoglanoglu, S; Çelik, S; Esendagli, D; Toptay, H; Sertçelik, UÖ; Akgün, M
    The novel coronavirus pandemic poses a major global threat to public health. Our knowledge concerning every aspect of COVID-19 is evolving rapidly, given the increasing data from all over the world. In this narrative review, the Turkish Thoracic Society Early Career Taskforce members aimed to provide a summary on recent literature regarding epidemiology, clinical findings, diagnosis, treatment, prevention, and control of COVID-19. Studies revealed that the genetic sequence of the novel coronavirus showed significant identity to SARS-CoV and MERS-CoV. Angiotensin-converting enzyme 2 receptor is an important target of the SARS-CoV-2 while entering an organism. Smokers were more likely to develop the disease and have a higher risk for ICU admission. The mean incubation period was 6.4 days, whereas asymptomatic transmission was reported up to 25 days after infection. Fever and cough were the most common symptoms, and cardiovascular diseases and hypertension were reported to be the most common comorbidities among patients. Clinical manifestations range from asymptomatic and mild disease to severe acute respiratory distress syndrome. Several patients showed typical symptoms and radiological changes with negative RT-PCR but positive IgG and IgM antibodies. Although radiological findings may vary, bilateral, peripherally distributed, ground-glass opacities were typical of COVID-19. Poor prognosis was associated with older age, higher Sequential Organ Failure Assessment score, and high D-dimer level. Chloroquine was found to be effective in reducing viral replication in vitro. Likewise, protease inhibitors, including lopinavir/ritonavir, favipiravir, and nucleoside analogue remdesivir were proposed to be the potential drug candidates in COVID-19 management. Despite these efforts, we still have much to learn regarding the transmission, treatment, and prevention of COVID-19.