Browsing by Author "Akyuz M."

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    The hydration status and thyroid hormones levels among elite wrestlers
    (Mattioli 1885, 2019) Yagmur R.; Isik O.; Kilic Y.; Akyuz M.
    Study Objectives: Dehydration causes various loss of physical and physiological functions and also thyroid hormones are important for maintaining the normal physiological function of the body and regulate basic metabolism in the human body. The aim of this study was to examine the effect of pre-competition dehydration on elite wrestlers' thyroid hormones levels. Sixty-nine elite wrestlers participated in the study. Methods: The retrospective research model was used in the study. In previously obtained blood samples were determined Sodium (Na+), Blood Urea Nitrogen (BUN), Glucose, Potassium (K), Triiodothyronine (T3), Thyroxine (T4) and Thyroid Stimulating Hormone (TSH) levels. The wrestlers Posm levels were calculated using a mathematical formula and Posm levels >290 who wrestlers as the dehydration group and Posm levels ≤290 who wrestlers as the euhydration group were divided into two groups. The Kolmogorov-Smirnov test was used for the normality test of the data. The independent samples t-test was used in the analysis of the obtained data. Significance was set at 0.05. Results: According to the results of this study, it was determined that ∼45% of pre-competition wrestlers were exposed to dehydration. When the dehydration and euhydration groups were compared, there was a significant difference in BUN and Na+ levels as the hydration markers and there was no difference in Glucose and K levels. When the difference between thyroid hormones levels was examined, it was found that there was a statistical difference between T3 levels and there was no difference between T4 and TSH levels. Conclusion: T3 levels of elite wrestlers were lower in dehydration group than the euhydration group, whereas T4 and TSH levels were not different between both groups. © 1885 Mattioli.
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    Comparison of blood carbonic anhydrase activity of athletes performing interval and continuous running exercise at high altitude
    (Taylor and Francis Ltd, 2019) Tas M.; Senturk E.; Ekinci D.; Demirdag R.; Comakli V.; Bayram M.; Akyuz M.; Senturk M.; Supuran C.T.
    The effects of high-intensity interval and continuous exercise on erythrocytes carbonic anhydrase (CA, EC 4.2.1.1) activity levels were scarcely investigated up until now. Here we present a study focused on the CA activity from erythrocytes of athletes experiencing interval and continuous training for 6 weeks, during cold weather and at high altitude (> 1600 m). We observed a 50% increase in the blood CA activity at the second week after initiation of the training in both interval and continuos running groups, whereas the control group did not experience any variation in the enzyme activity levels. In the trained individuals a mild decrease in their body mass, BMI and an increased (Formula presented.) were also observed. The CA activity returned at the basal values after 4–6 weeks after the training started, probably proving that a metabolic compensation occurred without the need of an enhanced enzyme activity. The unexpected 50% rise of activity for an enzyme which acts as a very efficient catalyst for CO2 hydration/bicarbonate dehydration, such as the blood CA, deserves further investigations for better understanding the physiologic basis of this phenomenon. © 2018, © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
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    Effects of eccentric exercise-induced delayed onset muscle soreness on endoplasmic reticulum stress-related markers; [Eksantrik egzersize bagli gecikmis kas agrisinin endoplazmik retikulum stresle iliskili belirteçler üzerindeki etkileri]
    (De Gruyter Open Ltd, 2021) Dogru Y.; Varol S.R.; Nalcakan G.R.; Akyuz M.; Tas M.; Ulman C.
    Short Communications: Apelin, pentraxin3 (PTX3), and interleukin6 (IL6) parameters are known as inflammation markers and found to be related to endoplasmic reticulum (ER) stress. The aimof the studywas to investigate the effect of eccentric exercise-induced delayed onset muscle soreness (DOMS) on ER stress-related markers in young athletes. Objectives and Methods: ER stress and DOMS-related blood markers, maximal strength level, and rate of perceived exertion using the visual analog scale (VAS) were assessed before, immediately after, 24, 48, and 72 h after the muscle damage protocol. Results: IL6 peaked 24 h after while creatine kinase and lactate dehydrogenase enzyme levels reached their peaks at 72 h after the protocol. The level of apelin continued to increase throughout the four measurements, and PTX3 peaked at 24 h, and then declined to the levels before the protocol but the differences were not significant. The significant decrease in the strength and the significant increase in VAS continued 48 h after the protocol. Conclusion: ER is activated and ER stress occurred, due to increases in IL6, PTX3 and apelin levels after the test protocol concluded that a single vigorous eccentric exercise should be avoided in harmful effect on health as parallel with Physical Activity Guidelines Open Access. 2020 Yeliz Dogru et al. © 2021 De Gruyter. All rights reserved.