Browsing by Author "Alpdogan, G"

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    Polarographic determination of fluvoxamine maleate in tablets
    Elmali, F; Alpdogan, G; Sungur, S; Aycan, S
    The differential pulse polarographic (DPP) method was developed for the determination of fluvoxamine maleate (I). At pH = 3. 7, (I) give a peak at - 0. 73 V in aqueous solution. The developed method was applied to the assay of the drug substance in commercial tablet formulations. The results were statistically compared with those obtained by reference methods (HPLC and direct current polarographic method) using t- and F- tests at 95 % confidence level.
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    Differential pulse polarographic determination of enalapril maleate
    Elmali, F; Alpdogan, G; Aycan, S; Sungur, S
    A differential pulse polarographic (DPP) method has been developed for the quantitative analysis of enalapril maleate. Enalapril maleate gives a peak at -1.4 V in methanol. A calibration curve was constructed for the 20 -100 mug ml(-1) concentration range. As a reference method, a reversed phase high performance liquid chromatographic procedure has been developed. Commercially available tablets were analysed by the two methods. Statistical evaluations indicated that there was no significant difference between the mean values and precisions of the two methods at a 95% confidence level.