Browsing by Author "Altun, E"

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    Effects of Different Treatment Modalities on Lung Injury in Experimental Pulmonary Contusion Model
    Kuzucuoglu, M; Balta, C; Altun, E; Yekdes, AC; Acar, A
    Introduction: The study experimentally evaluated the efficacies of different agents in treating pulmonary contusion. Methods: In our study, 42 Wistar albino rats were divided into six groups of seven animals each. A model of lung contusion with blunt chest trauma was performed in five groups, except for the control group. One group with pulmonary contusion was considered an untreated group, and saline was administered. For other groups, prednisolone, tranexamic acid, N-acetylcysteine, and vitamin E were applied to determine their efficacy in treatment. The rats were sacrificed 24 h after trauma, and their injured lungs were collected for histopathological examination and blood samples for blood gas analysis. Histopathologically, bronchial damage, alveolar hemorrhage, emphysema, and leukocyte infiltration were assessed using the scoring system. Results: In our study, statistically significant differences were detected between the rat groups in terms of intraalveolar hemorrhage, leukocyte infiltration, and bronchial damage. In post hoc analysis, intraalveolar hemorrhage was significantly higher in the untreated group compared to the control group (P = 0.012). A near-significant difference was observed between the untreated group and the N-acetylcysteine group (P = 0.061). Regarding leukocyte infiltration, the tranexamic acid group showed significantly higher values compared to both the prednisolone and control groups (P = 0.007; P = 0.016, respectively). For bronchial damage, the levels observed in the vitamin E and tranexamic acid groups were significantly higher than those in the control group (P = 0.08 and P = 0.037, respectively). Conclusions: Many agents are used to treat pulmonary contusion, but no gold standard treatment exists. Prednisolone and N-acetylcysteine play significant roles in treatment. These two drugs contributed to the regression of the findings in pulmonary contusion treatment. 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
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    Developing a Science Process Skills Test for Secondary Students: Validity and Reliability Study
    Feyzioglu, B; Demirdag, B; Akyildiz, M; Altun, E
    Science process skills are claimed to enable an individual to improve their own life visions and give a scientific view/literacy as a standard of their understanding about the nature of science. The main purpose of this study was to develop a test for measuring a valid, reliable and practical test for Science Process Skills (SPS) in secondary education at basic and integrated levels. The test was developed according to the renewed 9th and 10th and 11th grades chemistry curriculum acquisitions of content, chemistry-technotogy-society-environment, communication, attitude value Participants of this study are 222 students from a vocational high school and the Anatolian school of Izmir, Turkey. The test consisted of 30 multiple-choice questions and the KR20 reliability coefficient of this test was calculated as 0.83. The test consisted of sub-dimensions as, observing, classifying, measuring, communicating, inferring, predicting, formulating hypotheses, identifying variables, designing investigations, acquiring data, organizing data, and interpreting it. The test is compatible with a model which consists of observing, measuring, acquiring data, formulating problems, designing investigations, organizing data, interpreting factors of literature. The results of the confirmatory factor analysis supported validity and reliability of the test.