Browsing by Author "Arslan, D"

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    Opinions of university students about female genital mutilation in Sudan
    Akbas, M; Birge, O; Arslan, D; Ozbey, EG
    Background: Female genital mutilation/cutting (FGM/C) is an illegal tradition commonly practiced in Sub-Saharan Africa and the Middle East. Despite a globalized world and developing social media, this harmful practice is currently still being implemented. Aims: We aimed to evaluate the opinions of university students regarding FGM/C. Methods: This descriptive study included 821 students who studied at Nyala University, Sudan, in January 2016. The students were questioned for the following: age, faculty, reasons for female circumcision, effects of female circumcision on female sexual functions and their views about the circumcision for their daughter. Results: The rate of FGM/C among female university students was 80.1%. Although 73% of the male students prefer to marry uncircumcised women, they also reported that FGM/C should be continued to be performed, and their future daughters should be circumcised (64.5%). Female students were against FGM/C for their future daughters (77.6%). Conclusions: This study shows that even educated individuals demand FGM/C in spite of knowing the harm. It is therefore suggested continuing educational studies on this subject.
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    EFFECTS OF ENVIRONMENTALLY FRIENDLY FLUIDIZED BED DRYING ON THE QUALITY OF Viburnum opulus
    Bölek, S; Mercan, M; Vursavas, M; Arslan, D; Yurddas, A
    Owing to their high antioxidant activity, fiber, vitamin and mineral content, dried fruits are healthy and nutritious snacks. However, some quality characteristics of fruits are adversely affected by drying. Therefore, drying temperature is very important to obtain healthy and nutritious dried products. Recently, fluidized bed drying technology has been spread all over the world as it is an efficient and environmentally friendly technique. This study investigated the effects of fluidized bed drying, which is a thermodynamic equilibrium drying technique, on quality characteristics of Viburnum opulus. For this aim, the V. opulus fruits were dried at 60 degrees C, 70 degrees C and 80 degrees C with an air flow rate of around 60 m(3)/h for 5 h, 4 h and 3 h respectively. The moisture contents of V. opulus fruits were reduced by half (for medium-high temperature cases) after 90 min of drying process. Thanks to environmentally friendly fluidized bed drying system, V. opulus fruits moved on the bed during drying. As the fruits did not stay in the same place, heat and mass transfer increased and uniform drying was achieved. Color, rehydration capacity, shrinking ratio, antioxidant activity, pH and sensory analysis were conducted to compare the sensory, chemical and physical properties of dried V. opulus fruits. The drying temperature affected the quality characteristics of V. opulus fruits significantly (p<0.05). The V. opulus fruits dried at 60 degrees C has the highest rehydration capacity and they were the most appreciated samples with regards of appearance, flavor and overall impression among the dried fruits (p<0.05).
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    Investigation of mechanical and tribological behavior of SiC and B4C reinforced Al-Zn-Mg-Si-Cu alloy matrix surface composites fabricated via friction stir processing
    Ayvaz, SI; Arslan, D; Ayvaz, M
    In this study, SiC and B4C reinforced Al-Zn-Mg-Si-Cu alloy matrix surface composites (SCs) were produced by friction stir processing (FSP) technique. Microstructural, mechanical, and tribological properties of produced SCs, and those of non-reinforced samples were examined. In B4C and SiC reinforced SCs fabricated by friction stir processing, approximately a 20% increase in hardness was achieved as compared to the base metal. The maximum microhardness values of B4C and SiC reinforced surface composites were determined as 88.1 and 89.7 HV, respectively. The tensile strengths of these samples were measured as 166.42 and 174.74 N.mm(-2), respectively. As a result of the tests performed under 3, 5, and 10 N applied loads, it was observed that the friction coefficient decreased in general with the applied load. A higher coefficient of friction was obtained in SiC reinforced SCs than those of B4C reinforced SCs and non-reinforced samples. It was determined that the wear rate of B4C reinforced SCs decreased by similar to 30-40% and SiC reinforced SCs by similar to 50-55% compared to non-reinforced samples. In the examinations, it was revealed that mechanically mixed layer formation effectively reduced wear rate in these samples compared to non-reinforced samples.
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    Improving the abrasion resistance of AISI 304L metallic biomaterial by microwave boriding
    Arslan, D; Uzun, RO
    Metallic materials are used as biomaterials thanks to their high mechanical properties. However, their low resistance to corrosion and abrasion reduces the biocompatibility of them. In this study, the abrasion resistance of AISI 304L metallic biomaterial was improved by pack-boriding with microwave hybrid heating. For this purpose, AISI 304L material was pack-borided by using EKABOR II powder for two, four and six hours in a microwave oven with a power of 2.9 kW and a frequency of 2.45 GHz at temperatures of 850 degrees C, 900 degrees C and 950 degrees C. A boride layer with a thickness ranging between 12.1 mu m-56.6 mu m was obtained on the surface as a result of boriding. The specific wear rate of the AISI 304L material pack-borided for four hours at 950 degrees C, which exhibits the highest wear resistance, has been determined as 1.04656 x 10(-5) mm(3)/Nm. The abrasion resistance of AISI 304L metallic biomaterial was increased 28 times by microwave boriding.
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    Safety and efficacy of single-incision sling for female stress urinary incontinence: 3 years' results
    Yildiz, G; Ceylan, Y; Ucer, O; Arslan, D; Çelik, O; Gunlusoy, B
    The purpose of this study was to investigate the success and complication rates of single-incision sling for treating stress urinary incontinence (SUI), with a 3-year follow-up. This study comprised 173 female patients with SUI or mixed urinary incontinence (MUI) with dominant SUI who underwent minisling procedure. All patients had positive cough stress test preoperatively; they were followed up for 3 years after surgery (1, 3, 6, 12 months, and yearly). Total follow-up was 36 months, and mean age 51 years (44-77); 128 (74 %) patients presented SUI and 45 (26 %) MUI. Objective and subjective cure and failure rates were 83.8 % (145 cases), 6.4 % (11 cases), and 9.8 % (17 cases), respectively. There were no differences in cure rates between 1 and 3 years. Mean body mass index was 28.7 (26.1-35.2), and mean operating time 7.9 min. (6.5-11.9). There were no major intraoperative complications. Eleven patients (6.4 %) had de novo urge incontinence that resolved using anticholinergic drugs; no patient had urinary retention. Vaginal mesh extrusion was reported in nine (5.2 %) patients. The minisling system attained high success rates at 3 years' follow-up. The procedure was easy to learn and has lower complication rate.
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    The Frequency of Lysosomal Acid Lipase Deficiency in Children With Unexplained Liver Disease
    Kuloglu, Z; Kansu, A; Selbuz, S; Kalayci, AG; Sahin, G; Kirsaclioglu, CT; Demirören, K; Dalgiç, B; Kasirga, E; Önal, Z; Islek, A; Eren, E; Hosnut, FÖ; Urganci, N; Yaman, A; Özkan, T; Bozbulut, E; Dogan, G; Eksi Bozbulut, N; Dogan, G; Durmaz Ugurcan, Ö; Usta, AM; Arslan, D; Akçam, M; Isik, IA; Ecevit, ÇÖ; Usta, Y; Özgür, T; Özçay, F; Balamtekin, N; Öztürk, Y; Balamtekin, N; Öztürk, Y; Cantez, S; Gülerman, F; Üstündag, GH; Emiroglu, HH; Karacabey, N; Comba, A; Erdemir, G; Aydogan, AU; Gökçe, S; Kuyum, P; Gülsan, M; Tosun, MS; Tokgöz, Y; Güven, B; Yüksekkaya, H; Tümgör, G; Eren, M; Baran, M; Gümüs, M; Canan, O; Kocamaz, H; Gerenli, N; Çakir, M; Agin, M; Hizli, S; Dogan, Y; Çeltik, Ç; Deveci, U; Balci Sezer, O
    Objectives: Evidence suggests that lysosomal acid lipase deficiency (LAL-D) is often underdiagnosed because symptoms may be nonspecific. We aimed to investigate the prevalence of LAL-D in children with unexplained liver disease and to identify demographic and clinical features with a prospective, multicenter, cross-sectional study. Methods: Patients (aged 3 months-18 years) who had unexplained transaminase elevation, unexplained hepatomegaly or hepatosplenomegaly, obesity-unrelated liver steatosis, biopsy-proven cryptogenic fibrosis and cirrhosis, or liver transplantation for cryptogenic cirrhosis were enrolled. A Web-based electronic data collection system was used. LAL activity (nmol/punch/h) was measured using the dried blood spot method and classified as LAL-D(<0.02), intermediate (0.02-0.37) or normal (>0.37). Asecond dried blood spot sample was obtained from patients with intermediate LAL activity for confirmation of the result. Results: A total of 810 children (median age 5.6 years) from 795 families were enrolled. The reasons for enrollment were unexplained transaminase elevation (62%), unexplained organomegaly (45%), obesity-unrelated liver steatosis (26%), cryptogenic fibrosis and cirrhosis (6%), and liver transplantation for cryptogenic cirrhosis (<1%). LAL activity was normal in 634 (78%) and intermediate in 174 (21%) patients. LAL-D was identified in 2 siblings aged 15 and 6 years born to unrelated parents. Dyslipidemia, liver steatosis, and mild increase in aminotransferases were common features in these patients. Moreover, the 15-year-old patient showed growth failure and microvesicular steatosis, portal inflammation, and bridging fibrosis in the liver biopsy. Based on 795 families, 2 siblings in the same family were identified as LAL-D cases, making the prevalence of LAL-D in this study population, 0.1% (0.125%-0.606%). In the repeated measurement (76/174), LAL activity remained at the intermediate level in 38 patients. Conclusions: Overall, the frequency of LAL-D patients in this study (0.1%) suggests that LAL-D seems to be rare even in the selected high-risk population.
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    An Observational Study from the Perspective of Rheumatology in the Management of Patients with Psoriatic Arthritis in Turkey - LOOP Study
    Dalkilic, E; Solmaz, D; Kucuksahin, O; Capkin, E; Derin, ME; Arslan, D; Noyan, F; Coskun, NB; Murat, S; Sendur, OF; Melikoglu, MA; Gursoy, S; Kaya, T; Sahin, A; Karkucak, M; Pirildar, T; Terzioglu, ME; Bes, C; Akar, S
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    Evaluation of 601 children with multisystem inflammatory syndrome (Turk MISC study)
    Yilmaz, D; Keles, YE; Emiroglu, M; Duramaz, BB; Ugur, C; Kocabas, BA; Celik, T; Ozdemir, H; Bayturan, S; Turel, O; Erdeniz, EH; Cakici, O; Taskin, EC; Erbas, IC; Genceli, M; Sari, EE; Caymaz, C; Kizil, MC; Sutcu, M; Demirbuga, A; Alkan, G; Bagci, Z; Dayar, GT; Ozkan, EA; Yilmaz, AT; Akca, M; Yesil, E; Kara, SS; Akturk, H; Yasar, B; Umit, Z; Uygun, H; Erdem, N; Buyukcam, A; Oncel, EK; Oz, SKT; Cetin, HS; Anil, AB; Yilmaz, R; Zengin, N; Uzuner, S; Albayrak, H; Borakay, O; Topal, S; Arslan, G; Yazar, A; Ozer, A; Kendirli, T; Kara, EM; Demirkol, D; Battal, F; Kosker, M; Akcan, OM; Kihtir, HS; Gul, D; Zararci, K; Alakaya, M; Kula, N; Celik, E; Petmezci, E; Evren, G; Aksay, AK; Konca, C; Sert, A; Arslan, D; Bornaun, H; Tekeli, O; Bal, A; Sahin, IO; Demir, S; Sap, F; Akyol, MB; Tanidir, IC; Donmez, YN; Ucar, T; Coban, S; Arga, G; Torun, SH; Karpuz, D; Celik, SF; Varan, C; Elmali, F; Oncel, S; Belet, N; Hatipoglu, N; Karabulut, ND; Turgut, M; Somer, A; Kuyucu, N; Dinleyici, EC; Ciftci, E; Kara, A
    Purpose Due to its link with the 2019 coronavirus, the multisystem inflammatory syndrome in children (MISC) has garnered considerable international interest. The aim of this study, in which MISC patients were evaluated multicenter, and the data of the third period of the Turk-MISC study group, to compare the clinical and laboratory characteristics and outcomes of MISC patients who did and did not require admission to an intensive care unit (ICU).Methods This retrospective multicenter observational study was carried out between June 11, 2021, and January 01, 2022. The demographics, complaints, laboratory results, system involvements, and outcomes of the patients were documented.Results A total of 601 patients were enrolled; 157 patients (26.1%) required hospitalization in the intensive care unit (ICU). Median age was 8 years (interquartile range (IQR) 4.5-11.3 years. The proportion of Kawasaki disease-like features in the ICU group was significantly higher than in the non-ICU group (56.1% vs. 43.2% p = 0.006). The ICU group had considerably lower counts of both lymphocytes and platelets (lymphocyte count 900 vs. 1280 cells x mu L, platelet count 153 vs. 212 cells x 10(3)/ mu L, all for p< 0.001). C-reactive protein, procalcitonin, and ferritin levels were significantly higher in the ICU group (CRP 164 vs. 129 mg/L, procalcitonin 9.2 vs. 2.2 mu g/L, ferritin 644 vs. 334 mu g/L, all for p< 0.001). Being between ages 5-12 and older than 12 increased the likelihood of hospitalization in the ICU by four [95% confidence intervals (CI)1.971-8.627] and six times (95% CI 2.575-14.654), respectively, compared to being between the ages 0-5. A one-unit increase in log d-dimer (mu g/L) and log troponin (ng/L) was also demonstrated to increase the need for intensive care by 1.8 (95% CI 1.079-3.233) and 1.4 times (95% CI 1.133-1.789), respectively. Conclusion: By comparing this study to our other studies, we found that the median age of MISC patients has been rising. Patients requiring an ICU stay had considerably higher levels of procalcitonin, CRP, and ferritin but significantly lower levels of lymphocyte and thrombocyte. In particular, high levels of procalcitonin in the serum might serve as a valuable laboratory marker for anticipating the need for intensive care.
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    Familial Mediterranean Fever Mutation Analysis in Pediatric Patients With Inflammatory Bowel Disease: A Multicenter Study
    Urganci, N; Ozgenc, F; Kuloglu, Z; Yüksekkaya, H; Sari, S; Erkan, T; Önal, Z; Çaltepe, G; Akçam, M; Arslan, D; Arslan, N; Artan, R; Aydogan, A; Balamtekin, N; Baran, M; Baysoy, G; Çakir, M; Dalgiç, B; Dogan, Y; Durmaz, Ö; Ecevit, Ç; Eren, M; Gökçe, S; Gülerman, F; Gürakan, F; Hizli, S; Isik, I; Kalayci, AG; Kansu, A; Kutlu, T; Karabiber, H; Kasirga, E; Kutluk, G; Hosnut, FÖ; Özen, H; Özkan, T; Öztürk, Y; Soylu, ÖB; Tutar, E; Tümgör, G; Ünal, F; Ugras, M; Ustundag, G; Yaman, A
    Background: the aim of the study was to evaluate familial Mediterranean fever (FMF) mutation analysis in pediatric patients with inflammatory bowel disease (IBD). The relation between MEFV mutations and chronic inflammatory diseases hos been reported previously. Methods: Children with IBD (334 ulcerative colitis (UC), 224 Crohn's disease (CD), 39 indeterminate colitis (IC)) were tested for FMF mutations in this multicenter study. The distribution of mutations according to disease type, histopathological findings, and disease activity indexes was determined. Results: A total of 597 children (mean age: 10.8 +/- 4.6 years, M/F: 1.05) with IBD were included in the study. In this study, 41.9% of the patients had FMF mutations. E148Q was the most common mutation in UC and CD, and M694V in IC (30.5%, 34.5%, 47.1%, respectively). There was a significant difference in terms of endoscopic and histopathological findings according to mutation types (homozygous/heterozygous) in patients with UC (P <.05). There was a statistically significant difference between colonoscopy findings in patients with or without mutations (P=.031, P=.045, respectively). The patients with UC who had mutations had lower Pediatric Ulcerative Colitis Activity Index (PUCAI) scores than the patients without mutations (P=.007). Conclusion: Although FMF mutations are unrelated to CD patients, but observed in UC patients with low PUCAI scores, it was established that mutations do not hove a high impact on inflammatory response and clinical outcome of the disease.