Browsing by Author "Arslan E."

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    Genetical and histological investigation of Turkish siblings with spina bifida occulta who had neurosurgical intervention
    (2009) Altintas N.; Umur Ş.; Vatansever S.; Temiz C.; Selçuki M.; Selçuki D.; Örenay S.; Arslan E.
    Spina bifida is the one of the most frequently occurring birth defects. More children have spina bifida than muscular dystrophy, multiple sclerosis, and cystic fibrosis combined. Occulta present type is a mild very common form of spina bifida. The reported frequency of occurrence of spina bifida occulta (SBO) varies widely, depending largely on the age groups included in a particular study. The most accurate estimate of occurrence rate is 17% of examined spines. In present study we have examined and compared two Turkish siblings with spina bifida occulta who had neurosurgical intervention. Clinical, histopathological and cytogenetical analyses had been performed on mother and both siblings (brother and sister) diagnosed with spina bifida occulta. Hypertrichosis on their low-backs was diagnosed in both siblings. Magnetic resonance imaging (MRI) studies revealed low conus medullaris and thick filum terminale in brother and sister. The brother somatosensory evoked potential (SEP) results showed lumbar conduction blockade which was not found in sister. Despite the brothers's thick and fatty filum terminale sisters's seemed to be normal. Filum terminale sections from both siblings had normal appearance but atypical structure with increased amount of connective tissue and hyalinization areas. Sections from 9 years old boy were also prominent in glial cells. Genetical analysis revealed normal caryotype in 13 years old sister (46,XX) , however deletions on chromosome 17 have been detected in 9 year-old brother [46,XY/46,XY,del(17)(q25) /47,+mar] and their mother [46,XX/46,XX,del(17)(q25)]. Our results show on strong correlation between the deletion of chromosome 17(q25) with genetical and histological results in both siblings with SBO. This is the first report of chromosome 17 (q25) deletion related to the SBO and its genetic connection with neural tube defects.
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    Effects of a 12-week structured circuit exercise program on physical fitness levels of children with autism spectrum condition and typically developing children
    (Taylor and Francis Ltd., 2022) Arslan E.; Ince G.; Akyüz M.
    Purpose: This study aimed to determine the effects of a circuit exercise program on the physical fitness parameters of children with atypical autism spectrum condition (ASC) and typically developing (TD) children. Method: Fourteen (14) boys with atypical autism (mean age: 10.07 ± 0.25 years; weight: 24.97 ± 0.64 kg; height: 126.79 ± 1.33 cm) and 14 typically developing boys (mean age: 10.07 ± 0.30 years; weight: 26.97 ± 0.55 kg; height: 126.50 ± 0.62 cm) participated in the study. The children were divided into four groups using a random coin toss: Autism Exercise Group (AEG), Autism Control Group (ACG), Typically Developing Exercise Group (TDEG), and Typically Developing Control Group (TDCG). Testing parameters from the Bruininks-Oseretsky test of gross motor proficiency (BOT-2) included running speed and agility, balance, bilateral coordination, and the standing long jump. Handgrip strength (both sides), reaction times (visual and auditory), and flexibility tests were also performed. The exercise program consisted of three 60-minute sessions per week for 12 weeks, using the most-to-least prompting method. Findings: Significant improvements were observed for AEG in running speed and agility, balance, standing long jump, reaction times, handgrip strength, and flexibility (p < 0.05). For TDEG, only the standing long jump scores failed to significantly improve (p <.05). Comparing AEG and TDEG pre- and post-test results, the former showed 30% greater development with respect to balance, standing long jump, auditory reaction time, and handgrip strength (p < 0.05). Conclusion: Based on the significant improvements in physical fitness parameters of AEG, we recommend that children with ASC start sports training immediately when diagnosed with autism and participate in structured physical activities with their peers. © The British Society of Developmental Disabilities 2020.
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    Evaluation of the Knowledge, Attitudes and Behaviors of Pregnant Women on Tetanus Vaccination; [Gebelerin Tetanos Aşısıyla İlgili Bilgi, Tutum ve Davranışlarının Değerlendirilmesi]
    (DOC Design and Informatics Co. Ltd., 2022) Çınar G.; Akdemir-Kalkan İ.; Yılmaz-Karadağ F.; Hocaoğlu M.; Deniz S.; Işık M.E.; Gülten E.; Erdem-Kıvrak E.; Tüzün T.; Torun A.; Ünlü G.; Uygun-Kızmaz Y.; Akgül F.; Arslan E.; Dindar K.; Doğan G.; Sarı S.; Bayındır Z.; Sarıcaoğlu E.M.; Kaplan-Atalay E.; Cavnar A.M.; Haliloğlu E.N.
    Objective: Tetanus, a vaccine-preventable disease, still has the potential to threaten human health. Immunization, especially in pregnant women, is critical as it protects both mother and baby. This study aims to evaluate the tetanus immunization status of pregnant women, their approach to the vaccine, and the factors affecting these. Methods: A 19-item questionnaire was applied to pregnant women from all over Turkey who applied to the hospital for any reason and agreed to participate. Results: A total of 5000 pregnant women from seven geographical regions, aged between 15 and 44 (mean 28±5.7) and whose gestational age was between 8 and 40 weeks (mean 22.07±8.5), participated in the study. %88.2 of them did not get vaccinated in their current pregnancy, and %23.2 of them didn’t plan to get vaccinated. When the reasons for not being vaccinated were questioned, %28.6 and %15.4 of them were afraid of side effects and harming the baby, respectively. In addition, %23.9 of them thought they didn’t need to be vaccinated, and %7.1 of them stated that the vaccine didn’t provide any protection. In univariate analysis, regions, age, gestational week, and the number of pregnancies resulting in delivery were found as factors that statistically significantly affected getting vaccinated, but in multivariate analysis, gestational week, education until secondary school, being followed by a family physician, history of more than three pregnancies, and being vaccinated in a previous pregnancy was found as an independent factor. Conclusions: Neonatal tetanus should be prevented not only because of its high mortality but also, the sequelae, and it can be prevented, minimized, or even completely eradicated by vaccination of pregnant women. For this purpose, every pregnant woman should be informed, and education and counseling support should be provided for vaccination against tetanus. © 2022, DOC Design and Informatics Co. Ltd.. All rights reserved.