Browsing by Author "Arslan F."

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    Examining acute changes in some serum biochemical markers of brain tissue damage after free and Greco-Roman style wrestling; [serbest ve grekoromen güreşi takiben beyin doku hasarını gösteren bazı serum biyokimyasal markerlerindeki akut deǧişimin i̇ncelenmesi]
    (Turkish Biochemistry Society, 2010) Arslan F.; Büyükyazi G.; Ulman C.; Taneli F.; Gözlükaya F.; Çalkan M.
    Purpose: This study aimed to examine the acute changes in some serum biochemical markers due to overloading in one match of Greco-Roman and free style wrestling competitions. Method: In a repeated measures design, serum samples were collected before and 20 minutes after the first matches of the wrestlers during local wrestling competitions; subsequently analyzed for S-100B and heart-type fatty acid-binding protein. Study groups composed of Greco-Roman (n=15) and free style (n=16) wrestling groups of ≥19 year-old, healthy, male wrestlers. All matches were video-recorded for trauma analyses for each player. Results: Study results showed increments of 109% (p=.007) and 145% (p=.001) in serum S-100B; 63% (p=.023) and 198% (p=.002) in heart-type fatty acid-binding protein levels from pre to post match in the free and Greco-Roman style groups, respectively. The comparison of the increases obtained in the measured parameters did not reveal significant differences between the groups. Conclusion: Due to the significant increases in serum markers, there may be a possible additive effect of traumas in causing brain injuries/head traumas in free and Greco-Roman style wrestling. However, different style wrestling did not affect serum markers indicating brain tissue damage differently. © TurkJBiochem.com.
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    Variables determining mortality in patients with Acinetobacter baumannii meningitis/ventriculitis treated with intrathecal colistin
    (Elsevier B.V., 2017) Ceylan B.; Arslan F.; Sipahi O.R.; Sunbul M.; Ormen B.; Hakyemez İ.N.; Turunc T.; Yıldız Y.; Karsen H.; Karagoz G.; Tekin R.; Hizarci B.; Turhan V.; Senol S.; Oztoprak N.; Yılmaz M.; Ozdemir K.; Mermer S.; Kokoglu O.F.; Mert A.
    Aim To examine the variables associated with mortality in patients with Acinetobacter baumannii-related central nervous system infections treated with intrathecal colistin. Materials and methods This multi-centre retrospective case control study included patients from 11 centres in Turkey, as well as cases found during a literature review. Only patients with CNS infections caused by multidrug-resistant or extensively drug-resistant Acinetobacter baumannii treated with intrathecal colistin were included in this study. The variables associated with mortality were determined by dividing the patients into groups who died or survived during hospitalisation, and who died or survived from Acinetobacter meningitis. Results Among the 77 cases enrolled in the study, 35 were found through a literature review and 42 were cases from our centres. Forty-four cases (57.1%) were male and the median age was 48 years (range: 20–78 years). Thirty-seven patients (48%) died during hospitalisation. The variables associated with increased all-cause mortality during hospitalisation included old age (odds ratio, 1.035; 95% confidence interval (CI), 1.004–1.067; p = 0.026) and failure to provide cerebrospinal fluid sterilisation (odds ratio, 0.264; 95% confidence interval, 0.097–0.724; p = 0.01). There is a trend (P = 0.062) towards higher mortality with using of meropenem during meningitis treatment. Fifteen cases (19%) died from meningitis. There were no significant predictors of meningitis-related mortality. Conclusions The mortality rate for central nervous system infections caused by multidrug-resistant or extensively drug-resistant Acinetobacter baumannii is high. Old age and failure to provide CSF sterilisation are associated with increased mortality during hospitalisation. © 2016