Browsing by Author "Atci I.B."

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    Comparison of the histopathologic outcome of three different allograft used for the repair of spinal dural defect in rats; [Ratlarda spinal dura defekt tamirinde kullanılan üç farklı allogreftin histopatolojik sonuçlarının karşılaştırılması]
    (Ege University Press, 2013) Atci I.B.; Demirçivi Özer F.; Mete M.; Çamlar M.; Kocaman Ü.; Akçay E.; Erşahin y.; Öner Ö.; Küpelioǧlu A.
    Purpose: Repairing of the duramater is one of the major factor that effects the mortality and morbidity of patients after neurosurgical approaches. The gold standard for repairing of duramater is watertight suture or duraplasty with autografts such as pericranium and/or temporal fascia. Sometimes edges of the dura mater generally are shrunken and the watertight suture of the dura becomes impossible especially in emergency conditions. In the present study, we aimed to determine the most effective artificial dural graft in experimental dural defect in rats. Materials and Methods: Twenty eights wistar albino rats weight ranging from 280-320 grams and equal numbers of male and female were used. The animals were divided into four groups. Control (n=7 Group-1), collagen matrix graft (n=7 Group-2), cellulose graft (n=7 Group-3) and teflon graft (n=7 Group-4). Rats were sacrificed after 30 days and their damaged dura were removed and sections were taken. All histological preparations examined using light microscope. Histological analysis focused on fibroblastic activation, new capillary formation, inflammatory reaction, foreign body reaction and capsule formation and results were compared. Results: While fibroblastic activation was observed most frequently in teflon graft group, new capillary formation, inflammatory reactions and capsule formation were most frequently seen in cellulose grafts group. Conclusion: This animal model for artificial dural grafts suggest that cellulose was the most effective dural substitute for repairing of defective dura.
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    Hemorrhagic Risk in Vestibular Schwannoma Surgeries: Insights and Implications
    (International Scientific Information, Inc., 2024) Tabanli A.; Yilmaz H.; Akçay E.; Benek H.B.; Atci I.B.; Mete M.
    Background: Vestibular schwannoma is a slow-growing benign tumor arising from the 8th cranial nerve. It can originate in the cerebellopontine angle (CPA). This retrospective study aimed to investigate the factors associated with outcomes following surgical resection of vestibular schwannoma in the CPA in 30 patients at a single center in Turkey, focusing on postoperative intratumoral hemorrhage. Material/Methods: Thirty patients (mean age 42.8 years, range 17-81) underwent vestibular schwannoma surgery via a lateral suboccipital retrosigmoid approach. Patients were categorized as ‘less bleeding’ (n=15) or ‘more bleeding’ (n=15) based on the intraoperative nature of the tumor. Demographic characteristics, tumor size, extent of resection, postoperative intratumor bleeding rates, morbidity, and mortality were evaluated. Results: Mean tumor size was significantly larger in highly hemorrhagic tumors (3.8 cm, range 2.1-5 cm) compared with less hemorrhagic tumors (2.1 cm, range 1.8-3 cm) (P<0.001). Total resection was achieved in 60% of patients with highly hemorrhagic tumors >3 cm and chronic diseases, compared with 80% in less hemorrhagic tumors (P=0.02). Postoperative intratumoral hemorrhage occurred in 83.3% of subtotal resections in highly hemorrhagic tumors, versus 6.7% in less hemorrhagic tumors (P<0.001). Conclusions: Larger vestibular schwannoma size is associated with increased hemorrhagic nature, complicating total resection. Subtotal resection in hemorrhagic tumors significantly increases the risk of postoperative bleeding and edema. When possible, total removal should be attempted to minimize complications. In cases requiring subtotal excision, careful postoperative management of coagulation and blood pressure is crucial. © Med Sci Monit, 2024.