Browsing by Author "Avci E."

Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    An important source of preanalytical error in medical laboratories: Centrifugation
    (De Gruyter Open Ltd, 2021) Sonmez C.; Gümüs A.; Senes M.; Aykal G.; Taneli F.; Aksungar F.; Avci E.; Coskun C.; Çinaroglu I.; Colak A.; Eker P.; Güçel F.; Hakligor A.; Inal B.B.; Orhan B.; Yilmaz C.
    Centrifugation separates particles within the specimen according to their shape, dimensions, and density and basically can be defined as a separation method. The centrifuge is an essential device in medical laboratories to prepare the serum, plasma, and urine samples for analysis. It is basically an electric device composed of the stationary (motor) and the motile (rotor) part. The centrifugation depends on two main variables: relative centrifugal force (RCF) and centrifugation time. The physical impact separating the specimen into its components in the centrifuge known as RCF is expressed as the multiples of gravitational acceleration (×g). RPM, defined as the number of rotations of the centrifuge perminute, shows the speed of the centrifuge. RCF value can be calculated by using RPM, and the centrifuge radius. Because models and sizes of centrifuges vary considerably, the use of gravity (g) forces instead of RPM is suggested. The centrifuges can be classified according to their usage, speed, technical specifications, and rotor type. An accurate and precise centrifugation process is essential to prevent errors in the preanalytical phase. The purpose of this document is to ensure the standardization of a good, precise protocol for the centrifugation process among the medical laboratories. © 2021 De Gruyter. All rights reserved.
  • No Thumbnail Available
    Item
    Seasonality in bipolar disorder: Impact on mood symptoms, psychosocial functioning, neurocognition, and biological rhythm; [Bipolar Bozuklukta Mevsimsellik: Duygudurum Belirtilerine, Psikososyal İşlevselliğe, Nörokognisyon ve Biyolojik Ritim Üzerine Etkisi]
    (Turkish Neuropsychiatric Society, 2021) Çökmüş F.P.; Aşçibaşi K.; Sücüllüoğlu Dikici D.; Çöldür E.Ö.; Avci E.; Aydemir Ö.
    Introduction: Even though an increase in the number of hospital admissions for manic and depressive periods at certain times of the year is reported in bipolar disorder (BD), mood symptoms do not show a seasonal variation. We aimed to find out the possible causes of increased hospital admissions of BD patients in certain periods of the year. Methods: The study was carried out in four centers in Turkey. The patient group consisted of 41 persons with a diagnosis of BD in remission. The healthy control (HC) group consists of 37 persons. The selected evaluation times are fall equinox (September 23), spring equinox (March 21), summer solstice (June 21) and winter solstice (December 21). For mood symptoms, Hamilton Depression Rating Scale and Young Mania Rating Scale; for functioning Functioning Assessment Short Test; for neurocognition Stroop Test (ST) and Rey Auditory Verbal Learning Test (RAVLT), for biological rhythm Biological Rhythms Interview of Assessment in Neuropsychiatry, and Seasonal Pattern Assessment Questionnaire were used. Results: In terms of mood symptoms no seasonal variation was found. Across all four periods of assessment of BD group, statistically significant variation was only observed in the instant recall, learning and recognition domains of RAVLT and word test and color test domains of ST; however, it was not sufficient to distinguish the BD group separating from the control group. Conclusions: In terms of mood symptoms, psychosocial functionality, biological rhythm, neurocognition, no seasonal variation was demonstrated that could distinguish the BD group from the HC group. © 2020 by Turkish Association of Neuropsychiatry.