Browsing by Author "Aydin O."

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    A retrospective multicenter evaluation of cutaneous melanomas in Turkey
    (Asian Pacific Organization for Cancer Prevention, 2014) Gamsizkan M.; Yilmaz I.; Buyukbabani N.; Demirkesen C.; Demiriz M.; Cetin E.D.; Ince U.; Akalin T.; Demirkan N.C.; Lebe B.; Erdem O.; Gokoz O.; Sakiz D.; Demireli P.T.; Astarci H.M.; Adim S.B.; Zemheri I.E.; Acikalin A.; Yaman B.; Aydin O.; Bassorgun C.I.
    Background: We defined melanoma distribution in a large series of Turkish patients and evaluated the prognostic parameters of melanomas. Materials and Methods: A total of 1574 patients' data was retrospectively collected at 18 centers in Turkey. Demographic characteristics were questioned and noted. Prognostic parametres were evaluated based on sentinel lymph node involvement. Results: Mean age was 56.7 (4-99) years. While 844 (53.6%) cases were male, 730 (46.4%) cases were female. One thousand four hundred forty-seven (92%) cases were invasive melanoma and 127 (8%) cases were in-situ melanoma. The most common histopathological form was the superficial spreading melanoma (SSM) which was found in 549 patients (37.9%). It was followed by nodular melanoma in 379 (26.2%), acral lentiginous melanoma (ALM) in 191 (13.2%) and lentigo maligna melanoma in 132 (9.1%), respectively. On univariate analysis, lymphovascular invasion (p < 0.001), tumor thickness (p < 0.001), histopathological subtype (p < 0.001), Clark level (p = 0.001), ulceration (p < 0.001), ≥ 6/mm2 mitosis (p = 0.005), satellite formation (p = 0.001) and gender (p = 0.03) were found to be associated with sentinel lymph node positivity. Regression was associated with sentinel lymph node negativity (p = 0.017). According to multivariate analysis, lymphovascular invasion and tumor thickness were significant independent predictive factors of SLN positivity. Patient age, tumor localization, precursor lesions, lymphocytic infiltration and neurotropism were not related with sentinel lymph node involvement. Conclusions: In this retrospective analysis, it was found that the prevalence of SSM is at a lower rate while the prevalence of ALM is at a higher rate when compared to western countries. According to Breslow index; most of the melanoma lesions' thickness were greater than 2 mm, corresponding Clark IV. Vascular invasion and tumor thickness are the most important factors for sentinel lymph node involvement.
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    The relationship between schizophrenia and kavum septum pellucidum: A case study
    (Yerkure Tanitim ve Yayincilik, 2014) Ascibasi K.; Aydin O.; Kuzu D.; Deveci A.
    Septum pellucidum that forming the medial wall of the lateral ventricles, a thin layer is formed by two laminae. Cavum septum pellucidum (CSP), a space between the two leaflets of the septi pellucidi, is thought to be a neurodevelopmental anomaly associated with schizophrenia. In normal fetal development, the formation of septum pellucidum occurs at the same time with the development of the neighboring limbic system structures such as hippocampus, amygdala, corpus callosum, septal nucleus. Therefore, the anatomical differences that are detected in the septum pellucidum may reflect the embryonal development disorders of the adjacent anatomical structures. Several magnetic resonance imaging studies have reported a higher prevalence of enlarged CSP in patients with schizophrenia than in normal subjects. In the literature of psychiatric disorders, CSP is most associated with schizophrenia. Wide CSP may support the neurodevelopmental etiology of schizophrenia. In this report we present a schizophrenia case. And we tried to discuss the patient's clinical appearance and neurocognitive disability.
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    The effect of medical education on attitudes towards schizophrenia: A five-year follow-up study
    (Turkish Association of Nervous and Mental Health, 2016) Danaçi A.E.; Balikçi K.; Aydin O.; Cengisiz C.; Burak Uykur A.
    Objective: It has been widely acknowledged that the community and health professionals hold negative attitudes toward patients with impaired mental health. This constitutes a major obstacle for those patients in coping with their disease, managing their care, and hence regulating their lives. Although studies carried out in Turkey document the presence of stigma, they provide limited information about ways for solving this problem. Drawing on the literature, the present study investigated the effect of medical education on stigmatization. Method: During the 2008/2009 academic year, 106 freshmen who were majoring in the Medical School at Celal Bayar University volunteered to participate in the present study. Participants had not yet received any theoretical or practical training in psychiatry. At the beginning of the study, they were informed about the purpose of the study and accordingly were requested to fill out a consent form. The 32-item schizophrenia subscale of the Attitude Questionnaire developed by the Psychiatric Investigations and Education Center (PAREM) was administered to the participants. Along with the questionnaire, they were also asked to provide demographic information. After 5 years, the participants who completed their psychiatry internship were reassessed with the same instrument. Results: 106 volunteers participated in the present study. The majority of the participants were female (54.7%) with equal balance of income and expenditures (65.1%) and a mental disease percentage of 5.6%. Findings showed that students' attitudes towards schizophrenic patients significantly changed positively as they proceeded from the first year to the fifth year. Results demonstrated that as students move through the years, they report more positive attitudes in the areas of etiology of schizophrenia (p < 0.01), treatment options (p < 0.01), approach to schizophrenic patients (p < 0.01), and social interactions (p < 0.01). Conclusion: We claim that the development of positive attitudes should be integrated into the mental health curriculum not only in particular years but also throughout the entire years of education. Along this continuum, we believe that students would become more aware of the needs of schizophrenic patients and gain an ongoing intuition toward the difficulties that the patients encounter. Viewed together, at the stage of acquiring medical/ psychological skills, students should be given the opportunity to have direct contact with patients in order to give adequate response to patients' needs and thus observe the improvement at the end of the treatment.
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    The developmental origins of metacognitive deficits in schizophrenia
    (Elsevier Ireland Ltd, 2016) Aydin O.; Balikci K.; Tas C.; Aydin P.U.; Danaci A.E.; Brüne M.; Lysaker P.H.
    The deficits in metacognition have been observed in schizophrenia but developmental roots of impaired metacognition are not well understood. Accordingly, this study compared metacognitive abilities of patients with schizophrenia and healthy group and examined the relationship between childhood trauma, attachment style and caregiver attitudes with metacognitive capacity which might contribute to metacognitive deficits in patient group. 35 patients with schizophrenia and 35 healthy people were included in the study. Metacognitive capacity was measured using the Metacognition Assessment Scale Abbreviated (MAS-A). This scale comprises four domains: self-reflectivity, understanding other's mind, decentration and mastery. Group comparisons revealed that schizophrenia patients had greater deficits in metacognitive ability. We found that the report of childhood emotional abuse, a pattern of anxious attachment and over protection by caregivers were uniquely related to metacognitive capacity. © 2016 Elsevier Ireland Ltd
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    Micro controller and computer based reactive power compensation; [Kompenzacija jalove snage zasnovana na mikro regulatoru i računalu]
    (Strojarski Facultet, 2017) Yilmaz E.N.; Aydin O.
    Reactive power compensation methods are one of the most effective methods to improve the efficiency of energy systems. Therefore, the designs and implementations of these systems are important. The aim of this study is to design and implement the most appropriate reactive power compensation systems in electrical power systems. Reactive power compensation can be realized using capacitors or the synchronous motors. In this study, a microcontroller and computer-controlled compensation applications are done by capacitors and synchronous motors under the same load conditions has been performed. By means of this designed system, it has been tried to determine what type of reactive power compensation is suitable in the existing system. In this respect, it is aimed to avoid unnecessary investments for existing systems and to establish a quality compensation system. In addition, the designed system is easy to update against all kinds of load changes and does not require additional equipment. © 2017, Strojarski Facultet. All rights reserved.
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    Reliability and validity of Turkish form of severity of acute stress symptoms scale; [DSM-5 Akut Stres Belirti Şiddeti Ölçeği Türkçe Formunun geçerliliği ve güvenilirliği]
    (Cukurova University, Faculty of Medicine, 2017) Aşçibaşi K.; Çökmüş F.P.; Aydemir Ö.; Aydin Aşik E.; Herdem A.; Alçi D.; Öztekin S.; Sarikavak T.; Aydin O.; Balikçi K.; Çöldür E.Ö.; Yüzeren S.; Sücüllüoğlu Dikici D.; Akdeniz F.; Köroğlu E.
    Objective: This study demonstrates the reliability and validity of the Turkish Form of Acute Stress Symptoms Scale which was developed according to DSM-5 criteria to measure the severity of acute stress disorder. Methods: This research was carried out with the patients who fulfilled the criteria of any stress related disorders according to DSM-5 criterion in inpatient and outpatient psychiatric clinics of Celal Bayar University, School of Medicine. Except for acute or post-traumatic stress disorders, patients with any other mental or physical disease were excluded. Fifty patients were included in the study. As the control group, 150 volunteers without any mental or physical diseases were invited. Beside Acute Stress Symptoms Scale, Peritraumatic Dissociative Experiences Questionnaire (PDEQ) which is the most commonly used self-rated instrument to rate the experience of recent trauma is utilized for concur-rent validity. In reliability analyses, internal consistency coefficient and item-total correlation coefficients were calcu-lated. In validity analyses, factor analysis and correlation analysis with PDEQ were performed. Results: The mean age of the study group was 32.1±12.0 years, and 57.7% of the sample group (n=116) were female. 31.3% of the group were college graduates, 36.3% primary school graduates, 29.9% is high school graduates. Disease duration in acute stress disorder group was 4.08±4.57 years. For the internal consistency of Acute Stress Symptoms Severity Scale, Cronbach’s alpha coefficient was found to be 0.95. Item-total score correlation coefficients were between 0.76 and 0.88 and all were statistically significant. For the exploratory factor analysis, sample adequacy was tested, Kaiser-Meier-Olkin (KMO) coefficients was 0.91 and Bartlett coefficient was 1388. Single-factor solution was obtained and the eigenvalue was 5.40, representing 77.8% of the total variance. Factor loadings of the items were between 0.82-0.92. The coefficient of correlation analysis with PDEQ was calculated as r=0.88. Area under the curve is found 0.99 as the result of ROC analysis. Conclusion: With these findings, it is shown that the severity of Acute Stress Symptoms Scale is reliable and valid for Turkish. © 2017 Anadolu Psikiyatri Derg. All rights reserved.
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    Reliability and validity of Turkish form of level 2 anxiety scale; [DSM-5 düzey 2 anksiyete ölçeği Türkçe formunun geçerliliği ve güvenilirliği]
    (Cukurova University, Faculty of Medicine, 2017) Aydin Aşik E.; Çökmüş F.P.; Aydemir Ö.; Aşçibaşi K.; Herdem A.; Çöldür E.Ö.; Alçi D.; Sarikavak T.; Öztekin S.; Balikçi K.; Yüzeren S.; Aydin O.; Akdeniz F.; Sücüllüoğlu Dikici D.; Köroğlu E.
    Objective: This study aims to demonstrate the reliability and validity of the Turkish Form of Level 2 Anxiety Scale developed according to DSM-5 criteria to measure the severity of panic disorder. Methods: This study was carried out with patients with a diagnosis of any anxiety disorder according to DSM-5 criteria who are under treatment in Celal Bayar University Faculty of Medicine Psychiatry inpatient or outpatient clinics. Patients with any mental or physical disease except for anxiety disorders were excluded. Accordingly, 54 patients with anxiety disorder were included in the study and these were distributed as panic disorder in seven patients, generalized anxiety disorder in two patients, agoraphobia in three patients, specific phobia in one patient, obsessive-compulsive disorder in two patients, somatization disorder in one patient and not otherwise specified anxiety disorder in 38 patients. As the healthy control group in 104 volunteers without any mental or physical disease were included. Beside Level 2 Anxiety Scale the most widely used self-rated scale, Spielberger’s State-Trait Anxiety Inventory was used for concurrent validity. In reliability analysis internal consistency coefficient and item-total correlation analysis; in validity analyses factor analysis and correlation analysis with the Spearman Correlation Analysis (SCA) was performed for validation. Results: The mean age of the study group was 28.23±11.7 years and 58.9% of the sample group (n=93) were female. 64.6% of the group were college graduates, 19.0% primary school graduates, 12.7% is also high school graduates. Disease duration of anxiety disorder group was 17.2±11.2 years. The internal consistency of the Level 2 Anxiety Scale was 0.94 and, item-total correlation coefficients of the Level 2 Anxiety Scale were between 0.68 and 0.88. In the exploratory factor analysis, for sample adequacy Kaiser- Meier-Olkin (KMO) coefficient was calculated as 0.90 and Bartlett coefficient was 1.08. Single-factor solution was obtained and the eigenvalue was 5.26, explaining 75.2% of the total variance. Factor loadings of the items were between 0.75 and 0.92. Coefficient of correlation analysis with SCA was calculated as r=0.45. Conclusion: These findings have been shown that the Level 2 Anxiety Scale is reliable and valid for Turkish. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
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    Reliability and validity of the Turkish version of DSM-5 level 2 anger scale; [DSM-5 İkinci Düzey Öfke Ölçeği Türkçe Formunun geçerliliği ve güvenilirliği]
    (Cukurova University, Faculty of Medicine, 2017) Çöldür E.Ö.; Öztekin S.; Aydemir Ö.; Sücüllüoğludikici D.; Akdeniz F.; Yüzeren S.; Alçi D.; Balikçi K.; Çökmüş F.P.; Aydin O.; Sarikavak T.; Aşçibaşi K.; Herdem A.; Aydin Aşik E.; Köroğlu E.
    Objective: The purpose of the present study was to investigate the reliability and validity of the Turkish Form of Level 2 Anger Scale. The scale was originally developed to measure the severity of anger regarding the DSM-5 criteria. Methods: This study was conducted in the Department of Psychiatry in Celal Bayar University Hospital. The participants were in- or out-patients diagnosed with any psychotic disorders according to the DSM-5. The exclusion criteria were comorbidity of other psychiatric disorders and/or physical diseases. The participants were 49 patients who were diagnosed with schizophrenia (n=40), schizoaffective disorder (n=3), and not otherwise specified psychotic disorder (n=6). One hundred and one volunteers without any mental or physical disease were also included to represent the healthy control. In the assesment beside Level 2 Anger Scale, 18-item Brief Psychiatric Rating Scale was used. In reliability analysis internal consistency coefficient and item-total correlation analysis were performed; for validity analysis exploratory factor analysis was performed. In concurrent validity correlation analyses between Level 2 Anger Scale and BPRS tension, hostility, uncooperativeness, and elated mood subscales were computed. In order to discriminate between the psychosis and the control group, group means of Anger Scale were compared with t-test. Results: The mean age of the study group was 26.0±10.3 and 52.7% of the sample group were female (n=79). 69.3% of them were graduated from university (n=104), 19.3% from high school (n=29), and 8% from elementary school. Disease duration of psychotic disorder group was 17.1±9.7 years. The internal consistency of the Level 2 Anger Scale was 0.91 and, item-total correlation coefficients were between 0.74-0.83. For the exploratory factor analysis of sample adequacy of Level 2 Anger Scale Kaiser-Meğer-Olkin (KMO) coefficients 0.81 and Bartlett coefficient 1.03 was found. Single-factor solution was obtained and the eigenvalue is 3.79, representing 75.80% of the total variance. Factor loadings of the items of the scale were between 0.83-0.90.The mean of score was 5.09±0.72 in the psychosis group while it was calculated as 3.65±0.36 in the control group. There was a statistically significant difference between the groups. There were moderate to high correlations between Level 2 Anger Scale and BPRS tension, hostility, uncooperativeness, and elated mood. Conclusion: Results demonstrated that the Turkish version of Level 2 Anger Scale is a valid and reliable. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
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    Reliability and validity of Turkish form of DSM-5 mania scale; [DSM-5 mani ölçeği Türkçe formunun geçerliliği ve güvenilirliliği]
    (Cukurova University, Faculty of Medicine, 2017) Öztekin S.; Alçi D.; Aydemir Ö.; Çökmüş F.P.; Aydin O.; Balikçi K.; Sarikavak T.; Akdeniz F.; Sücüllüoğlu Dikici D.; Aşçibaşi K.; Çöldür E.Ö.; Yüzeren S.; Herdem A.; Aşik E.A.; Köroğlu E.
    Objective: This study aimed to demonstrate the reliability and validity of the Turkish form of DSM-5 Mania Scale which was developed according to DSM-5 criteria to measure the severity of mania. Methods: This study was conducted with 50 patients who meet the diagnostic criteria of bipolar disorders according to DSM-5 criteria who are within manic or euthymic episode. The patients were under treatment at inpatient and outpatient clinics of Psychiatry Department of Celal Bayar University, Medicine Faculty. Patients with any mental or physical disease except bipolar disorders were excluded. Sixty-three volunteers without any mental or physical disease were in- cluded as healthy control group. Beside DSM-5 Mania Scale the most widely used scale Young Mania Rating Scale (YMRS) was used for concurrent validity. In reliability analyses internal consistency coefficient and item-total correlation analysis; in validity analyses factor analysis and correlation analysis with the Pearson Correlation Analysis were performed. Results: The mean ages of the bipolar disorders group (n=50) and healthy control group (n=63) were respectively 30.9±13.6 and 22.4±5.8. 53.7% of the sample group (n=58) were female. Disease duration of bipolar disorder group was 7.2±7.9 years. The internal consistency of the DSM-5 Mania Scale was 0.91 and, item-total correlation coefficients of the DSM-5 Mania Scale were between 0.67 and 0.85. In the explanatory factor analysis, for sample adequacy Kaiser- Meier-Olkin (KMO) coefficient was calculated as 0.85 and Bartlett coefficient was 389.51. Single-factor solution was obtained and the eigenvalue was 3.69, explaining 73.8% of the total variance. Factor loadings of the items were between 0.77-0.91. Significant and high levels of correlation were determined between YMRS and DSM-5 Mania Scale (r=0.78). Conclusion: These findings have been shown that the DSM-5 Mania Scale is reliable and valid for Turkish. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
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    Reliability and validity of turkish form of DSM-5 self-rated level 1 cross-cutting symptom scale-adult version; [DSM-5 birinci düzey kesitsel belirti ölçeği türkçe erişkin formunun geçerliliği ve güvenilirliği]
    (Cukurova University, Faculty of Medicine, 2017) Çökmüş F.P.; Balikçi K.; Aydemir Ö.; Akdeniz F.; Sücüllüoğlu Dikici D.; Yüzeren S.; Alçi D.; Öztekin S.; Çöldür E.Ö.; Aydin O.; Sarikavak T.; Aşçibaşi K.; Herdem A.; Aydin Aşik E.; Köroğlu E.
    Objective: The aim of this study is to demonstrate the reliability and validity of the Turkish Form of DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Scale Adult Version which is developed according to DSM-5 criteria to measure the severity of general symptomatology. Methods: This research was carried out with patients and their relatives who fulfilled the criteria of any psychiatric disorder according to DSM-5 criteria in inpatient and outpatient psychiatric clinics of Manisa Celal Bayar University, School of Medicine and healthy control group without any mental or physical disease. Accordingly, the distribution of psychiatric diagnosis of the patients were as follows: 39 patients with major depressive disorder, three patients with panic disorder, two patients with obsessive-compulsive disorder, four patients with schizophrenia, two patients with schizoaffective disorder, seven patients with BTA anxiety disorder, two patients with conversion disorder and post-traumatic stress disorder in one patient. Beside Level 1 Cross-Cutting Symptom Scale, the most widely used for general semptomatology self-rated scale, Symptom Check List-90-Revised Form (SCL-90-R) was used for concurrent validity. In reliability analysis internal consistency coefficient and item-total correlation analysis; in validity analyses exploratory factor analysis and correlation analysis with the SCL-90-R and subscales was performed for validation. Results: This research was carried out with 206 volunteers. 61.2% of the sample group (n=126) were female and the mean age of the study group was 35.1±11.2 years. 29.6% of the group were college graduates, 36.4% primary school graduates, 7.8% middle school graduates and 23.3% were also high school. The internal consistency of the Level 1 Cross-Cutting Symptom Scale was 0.94 and, item-total score correlation coefficients of the Level 1 Cross-Cutting Symptom Scale were between 0.30-0.79. In the exploratory factor analysis, for sample adequacy Kaiser-Meier-Olkin (KMO) coefficient was calculated as 0.92 and Bartlett coefficient was 3007.76. Three-factor solution was obtained, representing 60.8% of the total variance. In the analysis of the correlation between the subscales of SCL-90-R and subscales of the Level 1 Cross-Cutting Symptom Scale were as follows; for depression r=0.72, for anxiety r=0.80, for somatization r=0.72, for psychosis r=0.70, for obsessive compulsive symptoms r=0.68, for personality r=0.72, for suicide r=0.53, for sleep r=0.76, for anger r=0.64 and for the total score r=0.87 was obtained. Conclusion: These findings show that the Level 1 Cross-Cutting Symptom Scale is reliable and valid for Turkish. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
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    Reliability and validity of Turkish version of DSM-5 level 2 depression adult scale; [DSM-5 düzey 2 depresyon erişkin ölçeği Türkçe formunun geçerliliği ve güvenilirliği]
    (Cukurova University, Faculty of Medicine, 2017) Aydin Aşik E.; Çöldür E.Ö.; Aydemir Ö.; Aşçibaşi K.; Herdem A.; Alçi D.; Sarikavak T.; Çökmüş F.P.; Öztekin S.; Balikçi K.; Yüzeren S.; Aydin O.; Akdeniz F.; Sücüllüoğlu Dikici D.; Köroğlu E.
    Objective: This study aims to demonstrate the reliability and validity of Turkish version of DSM-5 Level 2 Depression Adult Scale which was developed to measure the severity of depression. Methods: The study group included 51 in or out-patients who met the criteria for major depressive disorder according to DSM-5. Sixty-five volunteers without any mental or physical disease were also recruited as a control group. Beck Depression Inventory (BDI), which is the most widely used self-report scale, was used for concurrent validity. Internal consistency coefficient and item-total correlation analysis were performed for reliability. Exploratory factor analysis was used for validity, as BDI was used for concurrent validity. Results: Mean age was 40.5±11.4 in the patient group and 21.8±4.9 years in the control group, respectively. 62.1% of the sample group (n=72) were female. 59.5% of the group were college graduates, 16.4% were primary school graduates and 14.7% were high school graduates. Disease duration for major depressive disorder was 13.5±10.5 years for the patient group. The internal consistency of the Level 2 Depression Adult was 0.96. Item-total correlation coefficients were between 0.71 and 0.90. For the exploratory factor analysis of sample adequacy of DSM-5 Level 2 Depression Adult Scale, Kaiser-Meger-Olkin (KMO) coefficient and Bartlett coefficient was calculated as 0.91 and 1026.62, respectively. Single-factor solution was obtained with an eigen value of 6.27, representing 78.3% of the variance. Factor loadings of the items were between 0.77 and 0.92. Correlation coefficient of Level 2 Depression Adult Scale with BDI was found as r=0.76. Conclusion: The Turkish version of DSM-5 Level 2 Depression Adult Scale is reliable and valid. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
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    Reliability and validity of Turkish form of repetitive thoughts and behaviors scale; [DSM-5 Yineleyici Düşünceler ve Davranışlar Ölçeği Türkçe Formunun geçerliliği ve güvenilirliği]
    (Cukurova University, Faculty of Medicine, 2017) Aşçibaşi K.; Öztekin S.; Aydemir Ö.; Aydin Aşik E.; Poyraz Çökmüş F.; Herdem A.; Alçi D.; Sarikavak T.; Aydin O.; Balikçi K.; Çöldür E.Ö.; Yüzeren S.; Sücüllüoğlu Dikici D.; Akdeniz F.; Köroğlu E.
    Objective: This study demonstrates the reliability and validity of the Turkish form of Repetitive Thoughts and Behaviors Scale (RTBS) which is developed according to DSM-5 criteria to measure the severity of obsessive-compulsive disorders (OCD). Methods: This research was carried out with 30 patients who fulfilled the criteria of obsessive compulsive disorders according to DSM-5 criterion in inpatient and outpatient psychiatric clinics of Celal Bayar University, School of Medicine. As the control group, 30 volunteers without any mental or physical diseases were invited. Besides RTBS, Maudsley Obsessive Compulsive Questionnaire (MOCQ) which is the most commonly used self-report scale was used for concurrent validity. In reliability analyses, internal consistency coefficient and item-total correlation coefficients were calculated. In validity analyses, factor analysis and correlation analysis with MOCQ were performed as well as ROC analysis. Results: The mean age of the study group was 31.2±9.7 years, and 65% of the sample group (n=39) were female. 56.7% of the group were college graduates, 25% high school graduates, 18.3% primary school graduates. Disease duration in the obsessive-compulsive disorder group was 7.5±6.1 years. The internal consistency of the RTBS 0.97 and, item-total correlation coefficients of the RTBS be-tween 0.86 and 0.95 was obtained. For the exploratory factor analysis, sample adequacy was tested, Kaiser-Meier-Olkin (KMO) coefficient was 0.87 and Bartlett’s coefficient was 436.89. Single-factor solution was obtained and the eigenvalue was 4.50, representing 90.1% of the total variance. Factor loadings of the items were between 0.91-0.97. The coefficient of correlation analysis with MOCQ was calculated as r=0.71. The area under the curve in ROC analysis was 0.93. Conclusion: With these findings, it is shown that RTBS is reliable and valid for Turkish Form. © 2017 Anadolu Psikiyatri Derg. All rights reserved.
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    Reliability and validity of Turkish form of sleep disorder scale; [DSM-5 Uyku Bozukluğu Ölçeği Türkçe Formunun geçerliliği ve güvenilirliği]
    (Cukurova University, Faculty of Medicine, 2017) Yüzeren S.; Herdem A.; Aydemir Ö.; Aydin O.; Balikçi K.; Sarikavak T.; Akdeniz F.; Sücüllüoğlu Dikici D.; Aşçibaşi K.; Çöldür E.; Alçi D.; Öztekin S.; Aydin Aşik E.; Köroğlu E.
    Objective: This study, demonstrate the reliability and validity of the Turkish form of DSM-5 Sleep Disorder Scale which improved according to DSM-5 criteria to measure the intensity of sleep disorder. Methods: This study were carried out with patients fulfilling the diagnosis of any sleep disorder according to DSM-5 criteria and who are undergoing treatment in Celal Bayar University Hospital sleep medicine inpatient or outpatient clinic. Patients with any mental or physical disease except for anxiety disorders were excluded. As a result, 50 patients with sleep disorder were included in the study and diagnoses of OSAS in 41 patients, primer insomnia in five patients, parasomnia in three patients and narcolepsia in one patient were made. Without any mental or physical disease in 50 volunteers formed the control group. Beside the DSM-5 Sleep Disorder Scale, the most widely used scale for sleep disorders, Pittsburgh Sleep Disorder Index (PSQI), was used for validation. Internal consistency coefficient and item-total score correlation analysis for reliability analysis; factor analysis and correlation analysis with the PSQI, and ROC analysis for discrimination between the sleep disorder and healthy control group for validity were performed. Results: The mean age of the study group was 39.3±15.8 years and 47.0% of the sample group (n=47) were female. 55.0% of the group were college graduates, 22.0% primary school graduates, 18.0% were high school graduates. Disease duration of sleep disorder group was 16.8±12.6 years. The internal consistency of the DSM-5 Sleep Disorder Scale was 0.91 and, item-total score correlation coefficients of the DSM-5 Sleep Disorder Scale were between 0.61 and 0.81. For the factor analysis, the sample adequacy of DSM-5 Sleep Disorder Scale was determined with Kaiser-Meier-Olkin (KMO) analysis where the coefficient was 0.91 and Bartlett analysis where chi-square was 1.54. Single-factor solution was obtained and the eigenvalue is 5.07 representing 63.4% of the total variance. Factor loadings of the items of the scale were between 0.69-0.87. Coefficient of correlation analysis with PSQI was calculated as r=0.727. In the ROC analysis, the area under the curve was obtained as 0.76. Conclusion: These findings have been shown that the DSM-5 Sleep Disorder Scale is reliable and valid for Turkish. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
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    Reliability and validity of Turkish form of agoraphobia scale; [DSM-5 agorafobi ölçeği Türkçe formunun geçerliliği ve güvenilirliği]
    (Cukurova University, Faculty of Medicine, 2017) Aydin O.; Çöldür E.Ö.; Aydemir Ö.; Balikçi K.; Çökmüş F.P.; Öztekin S.; Herdem A.; Aşçibaşi K.; Sarikavak T.; Akdeniz F.; Alçi D.; Yüzeren Başsivri S.; Sücüllüoğlu Dikici D.; Aydin Aşik E.; Köroğlu E.
    Objective: The purpose of the present study was to investigate the validity and reliability of the Turkish Form of the Agoraphobia Scale. The scale was originally developed to measure the severity of agoraphobia regarding the DSM- 5 criteria. Methods: This study was conducted at the Department of Psychiatry in Celal Bayar University Hospital. The participants were in- or out-patients diagnosed with any anxiety disorder according to the DSM-5. The exclusion criteria were comorbidity of other psychiatric disorders and/or physical diseases. Accordingly, 50 patients with anxiety disorder were included in the study and these were distributed as panic disorder in 14 patients, generalized anxiety disorder in 10 patients, agoraphobia and obsessive-compulsive disorder in four patients, post-traumatic stress disorder in one patient and not otherwise specified anxiety disorder in 17 patients. One hundred and three volunteers without any mental or physical disease were also included to represent the healthy control. Additionally the most widely used self-rated scale of the Spielberger’s State-Trait Anxiety Inventory was used for concurrent validity. Reliability analysis was performed to examine the internal consistency of the Turkish version of the scale. Additionally, item-total correlations were reported. In terms of examining the validity of the scale, subgroup validity analysis was conducted to investigate whether two groups of patients differ in their scores on the scale. ROC analysis was also performed. Results: The mean age of the study group was 29.0±11.8 and 60.1% of the sample group (n=92) were female. 66.0% of the group were college graduates, 19.0% primary school graduates, 15.0% is also high school graduates. Disease duration of anxiety disorder group was 17.1±9.7 years. The internal consistency of the Agoraphobia Scale was 0.95 and, item-total score correlation coefficients of the Agoraphobia Scale were between 0.66 and 0.87. In the explanatory factor analysis, for sample adequacy Kaiser-Meier-Olkin (KMO) coefficient was 0.92 and Bartlett coefficient was 1.57. Single-factor solution was obtained and the eigenvalue was 7.16, explaining 71.68% of the total variance. Factor loadings of the items were between 0.71 and 0.90. Coefficient of Spearman correlation analysis was r=0.31. Conclusion: Results demonstrated that the Turkish version of the Agoraphobia Scale was a valid and reliable instrument which may serve as useful in guiding future research that aims to measure agoraphobia severity. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
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    Validity and reliability of the turkish version of the clinician rated severity of autism spectrum and social communication disorders scale; [DSM-5 klinisyen tarafından puanlanan otizm spektrum ve toplumsal İletişim bozukluğu Şiddeti Ölçeği türkçe formunun geçerliliği ve güvenilirliği]
    (Cukurova University, Faculty of Medicine, 2017) Aydin O.; Çökmüş F.P.; Aydemir Ö.; Herdem A.; Balikçi K.; Sücüllüoğlu Dikici D.; Öztekin S.; Akdeniz F.; Sarikavak T.; Aşçibaşi K.; Çöldür E.; Alçi D.; Aşik E.A.; Yüzeren S.; Köroğlu E.
    Objective: The purpose of the present study was to investigate the validity and reliability of the Turkish form of the Clinician Rated Severity of Autism Spectrum and Social Communication Disorders Scale. The scale was originally developed to measure the severity of autism spectrum and social communication disorders regarding the DSM-5 criteria. Methods: The study was conducted in the Department of Psychiatry at Celal Bayar University Hospital. The participants were in- or out-patients diagnosed with any psychotic disorders according to DSM-5. The exclusion criteria were comorbidity of other psychiatric disorders and/or physical diseases. The study was carried out with a total of 49 patients who were diagnosed with schizophrenia (n=40), schizoaffective disorder (n=3), and not otherwise specified psychotic disorder (n=3). One hundred and one volunteers without any mental or physical disease were also included to represent the healthy control. Reliability analysis was performed to examine the internal consistency of the Turkish version of the scale. Additionally, item-total correlations were reported. In validity analyses, comparison of the total score of the scale in the patient and control groups was evaluated for the discriminative validity. ROC analysis was also performed. Results: 52.7% of the sample were male (n=79). 69.3% of them were graduated from university (n=104), 19.3% from high school (n=29), and 8% from elementary school (n=12). The mean age of the study group was 26.3±10.3 years. Disease duration of psychotic disorder group was 18,29±6.43 years. The internal consistency of the Autism Spectrum and Social Communication Disorder Scale was 0.81. Furthermore, item-total correlations revealed that all items in the scale contributed to the consistency of scores with item-total correlations approaching 0.70. The mean score of the scale in the patient group on the scale was 1.42 whereas the mean score of the healthy group was 0.0. The t-test analysis indicated that there was a statistically significant difference between the sample group and the healthy group in their scores on the scale. In the ROC analysis, the area under the curve was 0.84. Conclusion: Results demonstrated that the Turkish version of Autism Spectrum and Social Communication Disorder Scale was a valid and reliable instrument which may serve as useful in guiding future research that aims to understand autism spectrum and social communication disorder. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
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    Reliability and validity of Turkish form of DSM-5 severity measure for specific phobia; [DSM-5 Özgül Fobi Şiddet Ölçeği Türkçe Formunun geçerliliği ve güvenilirliği]
    (Cukurova University, Faculty of Medicine, 2017) Öztekin S.; Aydin O.; Aydemir Ö.; Çökmüş F.; Sarikavak T.; Sücüllüoğludikici D.; Aşçibaşi K.; Akdeniz F.; Alçı D.; Çöldür E.Ö.; Yüzeren S.; Herdem A.; Aydinaşik E.; Köroğlu E.
    Objective: This study aimed to demonstrate the reliability and validity of the Turkish form of DSM-5 Severity Measure for Specific Phobia Scale which was developed according to DSM-5 criteria to measure the severity of specific phobia. Methods: This study was carried out with patients with a diagnosis of any anxiety disorder according to DSM-5 criteria who are under treatment in Celal Bayar University Faculty of Medicine Psychiatry Inpatient or Outpatient Clinics. Patients with any mental or physical disease except for anxiety disorders were excluded. Accordingly, 50 patients with anxiety disorder were included in the study. One hundred and three volunteers without any mental or physical disease were included as healthy control group. Beside DSM-5 Severity Measure for Specific Phobia Scale the most widely used self-rated scale, Spielberger’s State-Trait Anxiety Inventory was used for concurrent validity. In reliability analyses internal consistency coefficient and item-total correlation analysis; in validity analyses factor analysis and correlation analysis with the Pearson Correlation Analysis were performed. Results: The mean age of the study group was 29.0±11.8 and 60.1% of the sample group (n=92) were female. 66.0% of the sample group were college graduates, 12.4% high school graduates, 21.6% were also primary school graduates. Disease duration of anxiety disorder group was 5.8±7.0 years. The internal consistency of the DSM-5 Severity Measure for Specific Phobia Scale was 0.79 and item-total correlation coefficients were between 0.33 and 0.78. In the explanatory factor analysis, for sample adequacy Kaiser-Meier-Olkin coefficient was calculated as 0.88 and Bartlett coefficient was 1.01. Double-factor solution was obtained and the eigenvalues were 5.45 and 1.26, explaining 67.20% of the total variance. Factor loadings of the items were between 0.43 and 0.88. Coefficient of correlation analysis with Spielberger’s State-Trait Anxiety Inventory was calculated as r=0.36. Conclusion: These findings have been shown that the DSM-5 Severity Measure for Specific Phobia Scale is reliable and valid for Turkish. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
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    The comparison of executive functions, social cognition and plasma oxytocin level between mothers' of schizophrenia patients and healthy control: Searching for a new endophenotype; [Şizofreni hastalarının anneleri ile sağlıklı kontrollerin yürütücü işlev, sosyal biliş ve plazma oksitosin düzeylerinin karşılaştırılması: Yeni bir endofenotip arayışı]
    (Cukurova University, Faculty of Medicine, 2017) Aydin O.; Balikçi K.; Taş C.; Ünal Aydin P.; Çökmüş F.P.; Esen Danaci A.
    Objective: Previous studies documented that there were a variety of endophenotypes that helped to diagnose as well as to predict functionality and treatment response. There is little, if any research that focused on investigating biochemical endophenotypes. Besides, the studies that include executive functions and social cognition, which were accepted as endophenotypes, have different results. In studies involving schizophrenia patients, the deficiency of oxytocin was found to be the most important hormone that would affect the treatment process. However, there have been no endophenotype studies that investigated the role of oxytocin hormone in the treatment process of schizophrenia patients. The purpose of the present study was twofold: (a) to detect new endophenotypes, and (b) to test endophenotypes that were previously found by focusing on the schizophrenia patients’ mothers. Methods: The participants were the healthy mothers of schizophrenia patients and healthy control group. They took the Reading the Mind in the Eyes Test, Wisconsin Card Sorting Test, and Wechsler Adult Intelligence Scale vocabulary subtest, respectively. In addition, participants’ blood samples were collected to include the level of plasma oxytocin as a biochemical in the data analyses. Results: Results revealed that there was a significant difference in plasma oxytocin levels for the healthy mother’s of schizophrenia patients and the healthy control group. Low level of plasma oxytocin level was found to be the only significant factor that differentiates the patients’ mothers and the healty control group. When the results of the Reading the Mind in the Eyes Test that measures executive functions, and the Wisconsin Card Sorting Test that measures social cognition were analyzed, no significant differences were found between the groups. Discussion: Our findings showed that oxytocin hormone could be a new endophenotype for schizophrenia. However, there is still a need for studies that focus on the investigation of detecting new endophenotypes. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
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    Reliability and validity of Turkish form of panic disorder scale; [DSM-5 panik bozukluğu ölçeği Türkçe formunun geçerliliği ve güvenilirliği]
    (Cukurova University, Faculty of Medicine, 2017) Balikçi K.; Herdem A.; Aydemir Ö.; Aydin O.; Çökmüş F.P.; Sücüllüoğlu Dikici D.; Öztekin S.; Akdeniz F.; Sarikavak T.; Aşçibaşi K.; Çöldür E.Ö.; Alçi D.; Aydin Aşik E.; Yüzeren S.; Köroğlu E.
    Objective: This study is to demonstrate the reliability and validity of the Turkish form of Panic Disorder Scale developed according to DSM-5 criteria to measure the severity of panic disorder. Methods: This study was carried out with patients with a diagnosis of any anxiety disorder according to DSM-5 criteria who are under treatment in Celal Bayar University Faculty of Medicine Psychiatry Inpatient or Outpatient Clinics. Patients with any mental or physical disease except for anxiety disorders were excluded. Accordingly, 50 patients with anxiety disorder were included in the study and these were distributed as panic disorder in 14 patients, generalized anxiety disorder in 10 patients, agoraphobia and obsessive-compulsive disorder in four patients, post-traumatic stress disorder in one patient and not otherwise specified anxiety disorder in 18 patients. As the healthy control group 103 volunteers without any mental or physical disease were included. Beside Panic Disorder Scale the most widely used self-rated scale, Spielberger’s State-Trait Anxiety Inventory was used for concurrent validity. In reliability analysis internal consistency coefficient and item-total correlation analysis; in validity analyses factor analysis and correlation analysis with the Spearman Correlation Analysis (SCA) was performed for validation. Results: The mean age of the study group was 29.0±11.8 years and 60.1% of the sample group (n=92) were female. 66.0% of the group were college graduates, 19.0% primary school graduates, 15.0% is also high school graduates. Disease duration of anxiety disorder group was 17.1±9.7 years. The internal consistency coefficient of the Panic Disorder Scale was 0.96 and, item-total correlation coefficients of the Panic Disorder Scale were between 0.68 and 0.88.In the exploratory factor analysis, for sample adequacy Kaiser-Meier-Olkin (KMO) coefficient was calculated as 0.92 and Bartlett coefficient was 1.57. Single-factor solution was obtained and the eigenvalue was 7.38, explaining 73.8% of the total variance. Factor loadings of the items were between 0.73 and 0.91. Coefficient of correlation analysis with SCA was calculated as r=0.32. Conclusion: These findings have been shown that the Panic Disorder Scale is reliable and valid for Turkish. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
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    Reliability and validity of Turkish version of DSM-5 depression scale; [DSM-5 depresyon ölçeği Türkçe formunun geçerliliği ve güvenilirliği]
    (Cukurova University, Faculty of Medicine, 2017) Sücüllüoğlu Dikici D.; Aşçibaşi K.; Aydemir Ö.; Balikçi K.; Akdeniz F.; Çöldür E.Ö.; Yüzeren S.; Alçi D.; Çökmüş F.P.; Öztekin S.; Aydin O.; Sarikavak T.; Herdem A.; Aydin Aşik E.; Köroğlu E.
    Objective: This study aims to demonstrate the reliability and validity of Turkish version of DSM-5 Depression Scale which was developed to measure the severity of depression. Methods: The study group included 50 in- or out-pa- tients who met the criteria for major depressive disorder according to DSM-5. Sixty-three healthy volunteers without any mental or physical disease were also recruited as a control group. Beck Depression Inventory (BDI), which is the most widely used self-report scale, was used for concurrent validity. Internal consistency coefficient Cronbach alfa and item-total correlation analysis were performed for reliability. Exploratory factor analysis was used for validity, as BDI was used for concurrent validity. Results: Mean age was 39.2±11.3 and 22.4±5.8 years in the patient and control group, respectively. Sixty-one percent of the sample group (n=66) were female. 64.8% of the group were college graduates, 19% were primary school graduates and 18.5% were high school graduates. Disease duration for major depressive disorder was 3.3±5.6 years for the patient group. For the internal consistency Cronbach alfa coefficient of the DSM-5 Depression Scale was 0.91. Item-total correlation coefficients were between 0.60-0.83. For the exploratory factor analysis of sample adequacy of DSM-5 Depression Scale, Kaiser-Meier-Olkin (KMO) coefficient and Bartlett coefficient was calculated as 0.91 and 608.18, respectively. Single-factor solution was obtained with an eigenvalue of 5.44, representing 60.4% of the variance. Factor loadings of the items were between 0.66-0.80. Correlation coefficient of DSM-5 Depression Scale with BDI was found as r=0.88. Conclusion: The Turkish version of DSM-5 Depression Scale is reliable and valid. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.
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    Reliability and validity of Turkish version of DSM-5 psychosis scale; [DSM-5 psikoz ölçeği Türkçe formunun geçerliliği ve güvenilirliliği]
    (Cukurova University, Faculty of Medicine, 2017) Herdem A.; Sücüllüoğlu Di̇ki̇ci D.; Aydemi̇r Ö.; Aydin O.; Aşçibaşi K.; Aydin Aşik E.; Sariikavak T.; Akdeni̇balikçi K.; Çöldür E.Ö.; Alçi D.; Çökmüş F.P.; Yüzeren S.; Öztekïn S.; Akdenïz F.; Köroğlu E.
    Objective: In this study we evaluated the reliability and validity of the Turkish version of DSM-5 Psychosis Scale developed in order to evaluate severity of psychosis in adult patients. Methods: This study was carried out with patients who met the diagnostic criteria for any psychotic disorder according to DSM-5 criteria and who are undergoing treatment in the inpatient and outpatient wards of Psychiatry Department of Celal Bayar University Medical School. Except for psychotic disorders patients with any mental or physical disease were excluded. A total of 49 patients (40 patients with schizophrenia, six patients with not otherwise specified psychotic disorder, three patients with schizoaffective disorder) were included in the study. One hundred and one volunteers without any mental or physical disease were included as the healthy control group. Reliability analysis was based on internal consistency and item-total score correlation. Validity analysis was based on exploratory factor analysis, comparison of mean scores of the patient and healthy control groups and ROC analysis. Results: The mean age of the study group was 26.0±10.3 years and 52.7% of the sample group (n=79) were female. Sixty-nine point three percent of the study group were college graduates, 8% primary school graduates, 19.3% is also high school graduates. Mean disease duration was 17.1±9.7 years in the psychotic disorder group. The internal consistency of the Psychosis Scale was 0.91 and, item-total correlation coefficients of the Psychosis Scale were between 0.25 and 0.82. In the factor analysis, for sample adequacy Kaiser- Meier-Olkin (KMO) coefficient was found as 0.81 and Bartlett coefficient as 1.03. Single-factor solution was obtained and the eigenvalue is 5.12, representing 64.0% of the total variance. Factor loadings of the items of the scale were between 0.33 and 0.88. The mean of score was 11.00±5.20 in patient group while it was calculated as 0.21±1.21 in control group. The area under the curve was calculated as 0.98 in the ROC analysis. Conclusion: These results indicate that the Turkish version of Psychosis Scale is reliable and valid. © 2017, Cukurova University, Faculty of Medicine. All rights reserved.