Browsing by Author "Ayhan, A"

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    OVARIAN IMMATURE TERATOMA IN PREGNANCY
    Hasdemir, P; Guvenal, T; Kandiloglu, A; Menekse, S; Ayhan, A
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    Effect of surgical staging on 539 patients with borderline ovarian tumors: A Turkish Gynecologic Oncology Group study
    Guvenal, T; Dursun, P; Hasdemir, PS; Hanhan, M; Guven, S; Yetimalar, H; Goksedef, BP; Sakarya, DK; Doruk, A; Terek, MC; Saatli, B; Guzin, K; Corakci, A; Deger, E; Celik, H; Cetin, A; Ozsaran, A; Ozbakkaloglu, A; Kolusari, A; Celik, C; Keles, R; Sagir, FG; Dilek, S; Uslu, T; Dikmen, Y; Altundag, O; Ayhan, A
    Objective. The objectives of this study were to examine demographic and clinicopathologic characteristics and to determine the effects of primary surgery, surgical staging and the extensiveness of staging. Methods. In a retrospective Turkish multicenter study, 539 patients, from 14 institutions, with borderline ovarian tumors were investigated. Some of the demographic, clinical and surgical characteristics of the cases were evaluated. The effects of type of surgery, surgical staging; complete or incomplete staging on survival rates were calculated by using Kaplan-Meier method. Results. The median age at diagnosis was 40 years (range 15-84) and 71.1% of patients were premenopausal. The most common histologic types were serous and mucinous. Majority of the staged cases were in Stage IA (735%). 242 patients underwent conservative surgery. Recurrence rates were significantly higher in conservative surgery group (8.3% vs. 3%). Of all patients in this study, 294 (545%) have undergone surgical staging procedures. Of the patients who underwent surgical staging, 228 (77.6%) had comprehensive staging including lymphadenectomy. Appendectomy was performed on 204 (37.8%) of the patients. The median follow-up time was 36 months (range 1-120 months). Five-year survival rate was 100% and median survival time was 120 months. Surgical staging, lymph node sampling or dissection and appendectomy didn't cause any difference on survival. Conclusion. Comprehensive surgical staging, lymph node sampling or dissection and appendectomy are not beneficial in borderline ovarian tumors surgical management. (C) 2013 Elsevier Inc. All rights reserved.
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    A Turkish Gynecologic Oncology Group study of fertility-sparing treatment for early-stage endometrial cancer
    Dursun, P; Erkanli, S; Güzel, AB; Gultekin, M; Tarhan, NC; Altundag, O; Demirkiran, F; Bese, T; Yildirim, Y; Bozdag, G; Yarali, H; Simsek, T; Ozcelik, B; Ortaç, F; Taskin, S; Guvenal, T; Ozgul, N; Haberal, A; Vardar, MA; Dede, M; Yenen, M; Altintas, A; Arvas, M; Ayhan, A
    Objective: To analyze the results of fertility-sparing treatment of early-stage endometrial cancer (EC) in patients treated at Turkish gynecologic oncology centers, and to present a review of the literature. Methods: Thirteen healthcare centers in Turkey were contacted to determine if they were eligible to participate in the study. Centers that were eligible and agreed to participate were sent a database form to record the demographic characteristics, clinicopathologic findings, and follow-up results for their EC patients. Results: Eleven Turkish healthcare centers provided data on 43 EC patients. Mean duration of treatment was 5 months and mean follow-up was 49 months. In total, 35 (81.4%) patients were tumor free following primary progesterone therapy. Mean time from the end of progesterone therapy to pregnancy was 10.6 +/- 4.3 months (range, 3-18 months). Two patients had tumor recurrence during follow-up. The pregnancy rate among the 31 women who actively sought pregnancy was 41.9% (n = 13). Conclusion: Conservative management of early-stage EC in women of reproductive age using oral progestins was effective and did not compromise oncological outcome. Pregnancy in the study patients was achieved spontaneously and artificially. (C) 2012 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
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    CLINICOPATHOLOGIC AND SURGICAL ANALYSIS OF 1090 PATIENTS WITH BORDERLINE OVARIAN TUMORS: A TURKISH SOCIETY GYNECOLOGIC ONCOLOGY (TRSGO) MULTI-INSTITUTIONAL RETROSPECTIVE TRIAL
    Guvenal, T; Demirkiran, F; Simsek, E; Yalcin, Y; Khatib, G; Gokulu, SG; Simsek, T; Dolapcioglu, K; Onan, A; Ozgul, N; Ortac, F; Yuksel, H; Altintas, A; Boso, B; Seyfettinoglu, S; Celik, C; Ureyen, I; Yalcin, I; Gungorduk, K; Senturk, B; Ayhan, A