Browsing by Author "Büyükyazi G."

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    Effects of continuous and interval running training on serum growth and cortisol hormones in junior male basketball players
    (2003) Büyükyazi G.; Karamizrak S.O.; Islegen Ç.
    Effects of two different eight-week aerobic training programs consisting of continuous (CR) or extensive interval running (IR) on serum growth (GH) and cortisol hormones in 33 male basketball players aged 15-16 were assessed. The CR group ran 4.8 km and the IR group ran 4 × 1.2 km, using equal work-to-rest ratio, three times per week. Aerobic power scores of all subjects and anaerobic power marks of the training subjects increased (p<0.01). Upon exertion, though serum GH levels increased in both exercise groups (p<0.01) prior to and following training; cortisol levels increased only in the IR group prior to training, and in both exercise groups following training (p<0.05). Following the eight week period, resting cortisol levels rose in the training (p<0.05) and control (p<0.01) groups. To conclude, an 8-week training program consisting of continuous or extensive interval running has been effective on acute GH and cortisol secretion in 15-16 year-old male athletes.
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    The effect of an eight-week walking program on bone turnover markers and sRANKL/osteoprotegerin levels in post-menopausal women; [Sekiz haftalik yürüme programinin menopoz sonrasi kadinlarda kemik döngüsügöstergeleri ve sRANKL/osteoprotegerin düzeyleri üzerine etkisi]
    (Turkiye Klinikleri, 2009) Büyükyazi G.
    Objective: To examine the effect of an eight-week moderate intensity walking program on bone turnover markers, serum osteoprotegerin (OPG) and soluble receptor-activator of nuclear factor- kappa β ligand (sRANKL) in postmenopausal women. Material and Methods: Twelve postmenopausal women (45-62 years) completed an eight-week walking program at moderate intensity (60-65% maximum heart rate reserve). Non-walking women served as the control group (CG; n= 11). Body weight, percent body fat, body mass index (BMI), estimated maximal oxygen consumption (estimated VO2max), bone turnover markers, sRANKL, serum OPG and sRANKL/OPG ratio were measured before and after the intervention. Results: Eight-week walking program produced significant increases in VO 2max and reductions in body weight and BMI. Serum intact parathyroid hormone (iPTH), and β- crosslaps (CTx) reduced (p< 0.01, for both), sRANKL/OPG ratio (p< 0.01) and sRANKL values (p< 0.05) increased in the exercise group (EG). We detected significant reductions in the serum OPG levels of EG and CG (p< 0.01). No significant differences were observed between the changes in EG and CG in terms of bone turnover markers, OPG and sRANKL values. Conclusion: Eight-week moderate intensity walking program is beneficial for improving cardiorespiratory function in postmenopausal women to enable them to lead a less risky and a more independent life; however, it seems not so effective in changing the bone turnover markers and the OPG/sRANKL system. Copyright © 2009 by Türkiye Klinikleri.
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    Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?
    (2009) Esen H.; Büyükyazi G.; Ulman C.; Taneli F.; Ari Z.; Gözlükaya F.; Tikiz H.
    Aim: To examine the effects of 10-week walking programs on maximal oxygen consumption, body composition, serum lipids, highly-sensitive C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand. Method: Twenty-seven middle-aged men (40-60years) walked for ten weeks, five days per week, 40-52min per day at either moderate or high intensity (∼5.95±0.26km/h and ∼7.64±0.36km/h; 50-55% and 70-75% maximum heart rate reserve, respectively). Non-walking, sedentary men served as controls (n=13). Estimated maximal oxygen consumption, body composition, lipid profile, highly-sensitive C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand were determined before and after the study. Results: After 10 weeks, estimated maximal oxygen consumption improved in both exercise groups (p<.05), favoring high-intensity group (p<.05). Body weight, percent body fat, and body mass index reduced significantly in both exercise groups (p<.05). Walking programs did not cause any significant changes in blood lipids, highly-sensitive Creactive protein, and osteoprotegerin levels; however, soluble receptor activator of nuclear factor-kappaβ ligand levels were found to decrease in high-intensity group (p<.05) and the change observed in both exercise groups was different from the change in control group (p<.05). Conclusion: For protective effects against cardiac risk factors and arterial calcification, high-intensity walking programs are advisable due to the greater improvements in soluble receptor activator of nuclear factor-kappaβ ligand and estimated maximal oxygen consumption. © TurkJBiochem.com.
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    Effects of Different Intensity Resistance Exercise Programs on Bone Turnover Markers, Osteoprotegerin and Receptor Activator of Nuclear Factor Kappa? Ligand in Post-Menopausal Women; [Farklı şiddetteki direnç egzersiz programlarının postmenopozal kadınların kemik turn-over markerleri, osteoprotegerin ve nükleer faktör kappa B reseptör aktivatör ligandı üzerine etkileri]
    (Turkiye Klinikleri, 2010) Karaarslan S.; Büyükyazi G.; Taneli F.; Ulmans C.; Tikiz C.; Gümüşer G.; Şahan P.
    Objective: To investigate the effects of 12-week two-different intensity resistance training programs on bone turnover markers, bone mineral density (BMD), osteoprotogerin (OPG), and soluble receptor activator of nuclear factor kappa β ligand (sRANKL) in postmenopausal women. Material and Methods: Forty healthy women (aged 45-60 years) participated in the study. High-intensity group (HIG; n=14) worked 4 days a week and performed two sets of 8-10 repetitions at ~70-80% of 1 repeat maximum (RM). Low-intensity group (LIG; n= 13) worked in the same duration, with 13-17 repetitions, at ~40-50% of 1RM. Control group (CG; n = 13) did not perform any exercises. Body composition, 1RM value for 10 exercises, repetitions of sit-ups for 30 seconds, bone formation and resorption markers, serum osteocalcine (OC), bone alkaline phosphatase (BAP), βCrossLabs, OPG, and sRANKL levels were measured before and after the training program. BMD was measured via dual energy X-ray absorptiometry. Results: Resistance training caused increases in spine BMD in HIG and LIG (p< 0.05), and OC levels increased in the HIG (p< 0.05). We observed a significant difference between the percent change in HIG versus the percent change in CG in the spine BMD values (p< 0.01). sRANKL levels decreased significantly in all three groups. Strength measures increased in both exercise groups (p< 0.001), favoring the HIG. Conclusion: High-intensity resistance training may be more effective for increasing muscle strength and protecting against osteoporosis and fractures. Due to insignificant changes in OPG levels and significant reductions in sRANKL in all groups, measures of circulating OPG and sRANKL levels seem not to be so useful to predict BMD or bone turnover status after resistance training programs. Therefore, these parameters remain to be determined directly in the bone microenvironments together with BMD measures and bone turnover markers.
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    Examining acute changes in some serum biochemical markers of brain tissue damage after free and Greco-Roman style wrestling; [serbest ve grekoromen güreşi takiben beyin doku hasarını gösteren bazı serum biyokimyasal markerlerindeki akut deǧişimin i̇ncelenmesi]
    (Turkish Biochemistry Society, 2010) Arslan F.; Büyükyazi G.; Ulman C.; Taneli F.; Gözlükaya F.; Çalkan M.
    Purpose: This study aimed to examine the acute changes in some serum biochemical markers due to overloading in one match of Greco-Roman and free style wrestling competitions. Method: In a repeated measures design, serum samples were collected before and 20 minutes after the first matches of the wrestlers during local wrestling competitions; subsequently analyzed for S-100B and heart-type fatty acid-binding protein. Study groups composed of Greco-Roman (n=15) and free style (n=16) wrestling groups of ≥19 year-old, healthy, male wrestlers. All matches were video-recorded for trauma analyses for each player. Results: Study results showed increments of 109% (p=.007) and 145% (p=.001) in serum S-100B; 63% (p=.023) and 198% (p=.002) in heart-type fatty acid-binding protein levels from pre to post match in the free and Greco-Roman style groups, respectively. The comparison of the increases obtained in the measured parameters did not reveal significant differences between the groups. Conclusion: Due to the significant increases in serum markers, there may be a possible additive effect of traumas in causing brain injuries/head traumas in free and Greco-Roman style wrestling. However, different style wrestling did not affect serum markers indicating brain tissue damage differently. © TurkJBiochem.com.
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    Comparison of some plasma inflammation markers in elite master athletes, recreational athletes and sedentary males; [Elit Master Atletler, Rekreasyonal Atletler ve Sedanter Erkeklerde Bazı Plazma İnflamasyon Markerlerinin Karşilaştinlmasi]
    (Turkiye Klinikleri, 2019) Gİrgİner F.; Büyükyazi G.; Ulman C.; Doğru Y.; Taneli F.; Yildiz R.; Taş M.; Keskİnoğlu P.
    Objective: It is known that high-intensity exercises lead to muscle damage and fibrosis. This study aims to compare some plasma inflammation markers in elite master athletes, recreational athletes and sedentary males to determine muscle injury. Material and Methods: 60 healthy male participants (min-max 45-65 years) were divided into 3 groups: Elite master athletes performing high intensity training (EMAG; n=22), recreational athletes performing moderate intensity training (RG; n=21) and sedentary controls (CG; n=17). Resting serum levels of the monocyte chemoattractant protein-1 (MCP-1), High-Sensitivity C-Reactive Protein (hsCRP), Tumor Necrosis Factor Alfa (TNF-α), Transforming Growth Factor Beta-1 (TGF-β-1), and Klotho hormone were compared among the groups. Results: Body weight, fat percentages, body mass index were lower and MaxVO2 was higher in EMAG than those of both RG and CG. TGF-β-1 and Klotho Hormone levels of EMAG and RG were higher than CG. Vitamin D levels of EMAG were found higher than those of CG. Conclusion: Regular long-term endurance training has a long-term positive impact on the regeneration of muscle damage and inflammation. The high levels of Klotho hormone determined in EMAG provides a longer and healthier life by extending the initiation process of many illnesses including metabolic diseases. © 2019 by Türkiye Klinikleri.