Browsing by Author "Başer K.H.C."
Now showing 1 - 5 of 5
Results Per Page
Sort Options
Item Traditional phytotherapy and trans-cultural pharmacy among Turkish migrants living in Cologne, Germany(2005) Pieroni A.; Muenz H.; Akbulut M.; Başer K.H.C.; Durmuşkahya C.This article reports on an ethnopharmaceutical field study carried out among Turkish migrants in Cologne, western Germany, which recorded 79 botanical taxa and 115 plant-based preparations, encompassing 167 folk phytotherapeutical uses, as well as a few other biological (animal and mineral derived) remedies. One-fourth of the recorded remedies were represented by food-medicines. Half of the ingredients quoted came originally from Turkey; only a few plants were gathered from the wild or cultivated in the Cologne area. This article discusses the Turkish migrants' frequent use of aerial parts of Sideritis species, the fruits of Pistacia terebinthus and the seeds of Peganum harmala from the perspective of modern phytopharmacology, phytotherapy and toxicology. It considers cultural adaptation related to the use of folk pharmaceuticals by analysing the ingredients of the Turkish folk pharmacopoeia and comparing them with those of the Turkish medical ethnobotany and of the phytotherapy of the host country (Germany). Only one third of the remedies mentioned by Turkish migrants living in Cologne are also known in German evidence-based phytotherapy, and less than 10% of the recorded phytotherapeutic uses are common to both pharmacopoeias. This article concludes by suggesting hypotheses on future changes affecting the knowledge and use of medicinal plants within the Turkish community of Cologne. © 2005 Elsevier Ireland Ltd. All rights reserved.Item Effect of a dietary essential oil mixture on performance of laying hens in the summer season(South African Bureau for Scientific Publications, 2006) Çabuk M.; Bozkurt M.; Alçiçek A.; Çatli A.U.; Başer K.H.C.The experiment was conducted to evaluate the effects of dietary supplements of either an essential oil mixture (EOM) or a mannan oligosaccharide (MOS) as alternatives to an antibiotic feed additive (avilamycin) for layers kept under hot summer conditions. Four hundred and eighty 54-week old Nick-Brown hens were assigned to four dietary treatments. Each treatment consisted of four replications of 10 cages (three hens per cage). The treatment groups were: 1) Control: Basal diet without additive; 2) Basal diet plus antibiotic (10 mg avilamycin/kg feed); 3) Basal diet plus 1 g MOS/kg feed; 4) Basal diet plus 24 mg EOM/kg feed. Performance of laying hens was affected by dietary treatments. Dietary supplementation of EOM and MOS significantly increased egg production compared with control and antibiotic groups. There were no significant differences in feed consumption between treatments. The EOM significantly improved feed conversion ratio above that of the control group. Egg weights were significantly different between treatments. Laying hens consuming MOS produced significantly lower egg weights than the other groups, while egg weights in the EOM, antibiotic and control groups did not differ significantly. Cracked-broken egg rate was decreased by dietary addition of EOM, MOS and antibiotic compared with the control. Number of deaths among hens was significantly affected by dietary treatments with the number of deaths in the MOS treatment being significantly lower than in the other treatments. The performance of laying hens during the summer season could be maintained with inclusions of EOM and MOS in the diet. © South African Society for Animal Science.Item Composition of the essential oil of endemic Haplophyllum megalanthum Bornm. from Turkey(2012) Ünver-Somer N.; Kaya G.I.; Sarikaya B.; Önür M.A.; Özdemir C.; Demircispi-Sup B.; Başer K.H.C.The composition of the essential oil produced from the flowering aerial parts of Haplophyllum megalanthum Bornm. (Rutaceae), endemic to Turkey, was analyzed by GC and GC-MS. Among the fifty-eight compounds constituting about 91.7% of the essential oil, the main components were characterized as palmito-γ-lactone (45.8%), octadecatrienoic acid (10.7%), linoleic acid (6.5%), octadecatetraenoic acid (6.3%) and nonacosane (4.8%). © 2011 Reproduction is free for scientific studies.Item Boswellia sacra essential oil manages colon cancer stem cells proliferation and apoptosis: a new perspective for cure(Bellwether Publishing, Ltd., 2021) Becer E.; Kabadayı H.; Başer K.H.C.; Vatansever H.S.Boswellia sacra Flueck essential oil is obtained from frankincense obtained from Boswellia sacra trees. The aim of this study was to investigate the in vitro anti-cancer activity of Boswellia sacra (BS) essential oil in CD133+ and CD133- Colo-320 cells. Essential oil was analyzed by GC-MS. CD133+ cells, cancer stem cells, were obtained from the Colo-320 by the MiniMACS system. Cytotoxicity were evaluated with MTT assay. Anti-cancer activity of BS essential oil was investigated by immunocytochemistry. 41 compounds were identified in the essential oil. 1:2 dilution BS essential oil was found to be active against all the cells for 24 h incubation. β-catenin immunoreactivity was significantly decreased in both BS essential oil-treated CD133+ and CD133- Colo-320 cells. Caspase-3 immunoreactivity significantly increased in BS essential oil-treated CD133- Colo-320 cells. We conclude that BS essential oil decreased β-catenin signaling molecules which play a crucial role in cancer cell proliferation. BS essential oil promoted apoptosis in CD133- Colo-320 cells. © 2020 Informa UK Limited, trading as Taylor & Francis Group.Item Cytotoxic activity and antioxidant effects of Origanum onites essential oil and its two major contents, carvacrol and p-cymene on human colorectal (HCT116) and hepatocelluler carcinoma (HepG2) cell lines(Taylor and Francis Ltd., 2022) Becer E.; Mutlu Altundag E.; Başer K.H.C.; Vatansever H.S.Origanum onites L. (O. onites) is one of the cultivated Origanum species in Turkey. The aim of this study was to determine the cytotoxicity and cellular antioxidant effects of O. onites essential oil, carvacrol and p-cymene on HCT116 and HepG2 cells. O. onites essential oil components were analyzed by GC/MS and GC/FID. Cytotoxicity was analyzed via the MTT assay in HCT116 and HepG2 cells. Cellular antioxidant activities of O. onites essential oil, carvacrol and p-cymene were determined with DCFH-DA method. GC/MS analysis identified carvacrol (%78.4) as the main constituent of O. onites essential oil. 400 µg/ml concentration of O. onites essential oil, carvacrol and p-cymene were found to be active against HCT116 and HepG2 cells. Also, carvacrol showed higher cellular antioxidant activity than O. onites essential oil and p-cymene. We conclude that O. onites essential oil and carvacrol may be a candidate for pharmaceutical products in treatment of cancer. © 2022 Informa UK Limited, trading as Taylor & Francis Group.