Browsing by Author "Baddal B."

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    Current situation of covid-19 in northern cyprus; [Situation actuelle de la covid-19 dans la partie nord de chypre]
    (World Health Organization, 2020) Sultanoglu N.; Baddal B.; Suer K.; Sanlidag T.
    Background: The public health burden of the novel coronavirus disease 2019 (COVID-19) is expected to increase and ur-gent strict measures by decision-makers is critical for the containment of the novel coronavirus (SARS-CoV-2) outbreak worldwide. Aims: This study aimed to give a real-time analysis of COVID-19 presence in northern Cyprus. Methods: All official SARS-CoV-2 positive cases were tracked and reported in terms of the origin, nationality, and transmission routes. Preventive measures taken after the first reported case were analyzed for their effectiveness as control strategies. Results: The index case of SARS-CoV-2 in northern Cyprus was identified as a female German tourist. First local case had travel history from the United Kingdom after which local transmission occurred. Rapid and strict containment measures have currently delayed a peak in observed cases. Conclusions: Rapid implementation of social-distancing measures, good hygiene measures and travel/gathering bans in northern Cyprus has been effective in controlling the outbreak. © World Health Organization (WHO) 2020.
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    In vitro Anti-Leishmanial Activity of Essential Oils Extracted from Plants Growing in Northern Cyprus Against Leishmania tropica; [Kuzey Kıbrıs’ta Yetişen Bitkilerden Elde Edilen Uçucu Yağlarda Leishmania tropica’ya Karşı in vitro Anti-leishmanial Etkinlik Araştırılması]
    (Galenos Publishing House, 2021) Güler E.; Özbilgin A.; Çavuş İ.; Baddal B.; Etikan İ.; Hüsnü Can Başer K.; Şanlıdağ T.
    Objective: Natural plant products are considered as a source of novel and effective compounds for the treatment of leishmaniasis. In this study, the in vitro activities of essential oils obtained from Origanum dubium (OD), Origanum majorana (OM), Salvia fruticosa (SF) and Laurus nobilis (LN) plants in Northern Cyprus were investigated against Leishmania tropica. Methods: Leishmania tropica strain (MHOM/TR/2012/CBCL-LT) was obtained. RPMI-1640 was added to 96-well plates in 100 µL aliquots, 100 µg/mL essential oil was added to the first well of each row and serial 2-fold dilutions were performed. A promastigote suspension was pipetted into all wells, and the plates were incubated. The promastigotes were enumerated using a haemocytometer. Results: OD essential oil was effective at killing all promastigotes at a minimum inhibitor height (MIC)=0.2 μg/mL and had high activity at the lowest concentrations. Both SF and LN oils had MIC=1.56 μg/mL and LD50 =0.78 μg/mL. SF was observed to impair promastigote morphology at the lowest concentrations, while LN did not exert any effect at concentrations <0.2 μg/mL. OM essential oil was found to have a MIC=3.13 μg/mL and a LD50 =1.56 μg/mL. Conclusion: All tested essential oils inhibited promastigotes of Leishmania tropica. OD essential oil demonstrated the highest anti-leishmanial activity. © 2021 Turkish Society for Parasitology.