Browsing by Author "Baena-Cagnani, CE"

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    Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA2LEN - ARIA Position Paper
    Bousquet, J; Anto, JM; Demoly, P; Schünemann, HJ; Togias, A; Akdis, M; Auffray, C; Bachert, C; Bieber, T; Bousquet, PJ; Carlsen, KH; Casale, TB; Cruz, AA; Keil, T; Carlsen, KCL; Maurer, M; Ohta, K; Papadopoulos, NG; Rodriguez, MR; Samolinski, B; Agache, I; Andrianarisoa, A; Ang, CS; Annesi-Maesano, I; Ballester, F; Baena-Cagnani, CE; Basagaña, X; Bateman, ED; Bel, EH; Bedbrook, A; Beghé, B; Beji, M; Ben Kheder, A; Benet, M; Bennoor, KS; Bergmann, KC; Berrissoul, F; Jensen, CB; Bleecker, ER; Bonini, S; Boner, AL; Boulet, LP; Brightling, CE; Brozek, JL; Bush, A; Busse, WW; Camargos, PAM; Canonica, GW; Carr, W; Cesario, A; Chen, YZ; Chiriac, AM; Costa, DJ; Cox, L; Custovic, A; Dahl, R; Darsow, U; Didi, T; Dolen, WK; Douagui, H; Dubakiene, R; El-Meziane, A; Fonseca, JA; Fokkens, WJ; Fthenou, E; Gamkrelidze, A; Garcia-Aymerich, J; van Wijk, RG; Gimeno-Santos, E; Guerra, S; Haahtela, T; Haddad, H; Hellings, PW; Hellquist-Dahl, B; Hohmann, C; Howarth, P; Hourihane, JO; Humbert, M; Jacquemin, B; Just, J; Kalayci, O; Kaliner, MA; Kauffmann, F; Kerkhof, M; Khayat, G; N'Goran, BK; Kogevinas, M; Koppelman, GH; Kowalski, ML; Kull, I; Kuna, P; Larenas, D; Lavi, I; Le, LT; Lieberman, P; Lipworth, B; Mahboub, B; Makela, MJ; Martin, F; Martinez, FD; Marshall, GD; Mazon, A; Melen, E; Meltzer, EO; Mihaltan, F; Mohammad, Y; Mohammadi, A; Momas, I; Morais-Almeida, M; Mullol, J; Muraro, A; Naclerio, R; Nafti, S; Namazova-Baranova, L; Nawijn, MC; Nyembue, TD; Oddie, S; O'Hehir, RE; Okamoto, Y; Orru, MP; Ozdemir, C; Ouedraogo, GS; Palkonen, S; Panzner, P; Passalacqua, G; Pawankar, R; Pigearias, B; Pin, I; Pinart, M; Pison, C; Popov, TA; Porta, D; Postma, DS; Price, D; Rabe, KF; Ratomaharo, J; Reitamo, S; Rezagui, D; Ring, J; Roberts, R; Roca, J; Rogala, B; Romano, A; Rosado-Pinto, J; Ryan, D; Sanchez-Borges, M; Scadding, GK; Sheikh, A; Simons, FER; Siroux, V; Schmid-Grendelmeier, PD; Smit, HA; Sooronbaev, T; Stein, RT; Sterk, PJ; Sunyer, J; Terreehorst, I; Toskala, E; Tremblay, Y; Valenta, R; Valeyre, D; Vandenplas, O; van Weel, C; Vassilaki, M; Varraso, R; Viegi, G; Wang, DY; Wickman, M; Williams, D; Wöhrl, S; Wright, J; Yorgancioglu, A; Yusuf, OM; Zar, HJ; Zernotti, ME; Zidarn, M; Zhong, N; Zuberbier, T
    Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies. Copyright (C) 2012 S. Karger AG, Basel
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    Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA2LEN and AllerGen)
    Bousquet, J; Khaltaev, N; Cruz, AA; Denburg, J; Fokkens, WJ; Togias, A; Zuberbier, T; Baena-Cagnani, CE; Canonica, GW; van Weel, C; Agache, I; Aït-Khaled, N; Bachert, C; Blaiss, MS; Bonini, S; Boulet, LP; Bousquet, PJ; Camargos, P; Carlsen, KH; Chen, Y; Custovic, A; Dahl, R; Demoly, P; Douagui, H; Durham, SR; van Wijk, RG; Kalayci, O; Kaliner, MA; Kim, YY; Kowalski, ML; Kuna, P; Le, LTT; Lemiere, C; Li, J; Lockey, RF; Mavale-Manuel, S; Meltzer, EO; Mohammad, Y; Mullol, J; Naclerio, R; Hehir, REO; Ohta, K; Ouedraogo, S; Palkonen, S; Papadopoulos, N; Passalacqua, G; Pawankar, R; Popov, TA; Rabe, KF; Rosado-Pinto, J; Scadding, GK; Simons, FER; Toskala, E; Valovirta, E; van Cauwenberge, P; Wang, DY; Wickman, M; Yawn, BP; Yorgancioglu, A; Yusuf, OM; Zar, H; Annesi-Maesano, I; Bateman, ED; Ben Kheder, A; Boakye, DA; Bouchard, J; Burney, P; Busse, WW; Chan-Yeung, M; Chavannes, NH; Chuchalin, A; Dolen, WK; Emuzyte, R; Grouse, L; Humbert, M; Jackson, C; Johnston, SL; Keith, PK; Kemp, JP; Klossek, JM; Larenas-Linnemann, D; Lipworth, B; Malo, JL; Marshall, GD; Naspitz, C; Nekam, K; Niggemann, B; Nizankowska-Mogilnicka, E; Okamoto, Y; Orru, MP; Potter, P; Price, D; Stoloff, SW; Vandenplas, O; Viegi, G; Williams, D
    Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an IgE-mediated inflammation of the membranes lining the nose. It is a global health problem that causes major illness and disability worldwide. Over 600 million patients from all countries, all ethnic groups and of all ages suffer from allergic rhinitis. It affects social life, sleep, school and work and its economic impact is substantial. Risk factors for allergic rhinitis are well identified. Indoor and outdoor allergens as well as occupational agents cause rhinitis and other allergic diseases. The role of indoor and outdoor pollution is probably very important, but has yet to be fully understood both for the occurrence of the disease and its manifestations. In 1999, during the Allergic Rhinitis and its Impact on Asthma (ARIA) WHO workshop, the expert panel proposed a new classification for allergic rhinitis which was subdivided into 'intermittent' or 'persistent' disease. This classification is now validated. The diagnosis of allergic rhinitis is often quite easy, but in some cases it may cause problems and many patients are still under-diagnosed, often because they do not perceive the symptoms of rhinitis as a disease impairing their social life, school and work. The management of allergic rhinitis is well established and the ARIA expert panel based its recommendations on evidence using an extensive review of the literature available up to December 1999. The statements of evidence for the development of these guidelines followed WHO rules and were based on those of Shekelle et al. A large number of papers have been published since 2000 and are extensively reviewed in the 2008 Update using the same evidence-based system. Recommendations for the management of allergic rhinitis are similar in both the ARIA workshop report and the 2008 Update. In the future, the GRADE approach will be used, but is not yet available. Another important aspect of the ARIA guidelines was to consider co-morbidities. Both allergic rhinitis and asthma are systemic inflammatory conditions and often co-exist in the same patients. In the 2008 Update, these links have been confirmed. The ARIA document is not intended to be a standard-of-care document for individual countries. It is provided as a basis for physicians, health care professionals and organizations involved in the treatment of allergic rhinitis and asthma in various countries to facilitate the development of relevant local standard-of-care documents for patients.
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    Development and implementation of guidelines in allergic rhinitis - an ARIA-GA2LEN paper
    Bousquet, J; Schunemann, HJ; Zuberbier, T; Bachert, C; Baena-Cagnani, CE; Bousquet, PJ; Brozek, J; Canonica, GW; Casale, TB; Demoly, P; Gerth van Wijk, R; Ohta, K; Bateman, ED; Calderon, M; Cruz, AA; Dolen, WK; Haughney, J; Lockey, RF; Lotvall, J; O'Byrne, P; Spranger, O; Togias, A; Bonini, S; Boulet, LP; Camargos, P; Carlsen, KH; Chavannes, NH; Delgado, L; Durham, SR; Fokkens, WJ; Fonseca, J; Haahtela, T; Kalayci, O; Kowalski, ML; Larenas-Linnemann, D; Li, J; Mohammad, Y; Mullol, J; Naclerio, R; O'Hehir, RE; Papadopoulos, N; Passalacqua, G; Rabe, KF; Pawankar, R; Ryan, D; Samolinski, B; Simons, FER; Valovirta, E; Yorgancioglu, A; Yusuf, OM; Agache, I; Ait-Khaled, N; Annesi-Maesano, I; Beghe, B; Ben Kheder, A; Blaiss, MS; Boakye, DA; Bouchard, J; Burney, PG; Busse, WW; Chan-Yeung, M; Chen, Y; Chuchalin, AG; Costa, DJ; Custovic, A; Dahl, R; Denburg, J; Douagui, H; Emuzyte, R; Grouse, L; Humbert, M; Jackson, C; Johnston, SL; Kaliner, MA; Keith, PK; Kim, YY; Klossek, JM; Kuna, P; Le, LT; Lemiere, C; Lipworth, B; Mahboub, B; Malo, JL; Marshall, GD; Mavale-Manuel, S; Meltzer, EO; Morais-Almeida, M; Motala, C; Naspitz, C; Nekam, K; Niggemann, B; Nizankowska-Mogilnicka, E; Okamoto, Y; Orru, MP; Ouedraogo, S; Palkonen, S; Popov, TA; Price, D; Rosado-Pinto, J; Scadding, GK; Sooronbaev, TM; Stoloff, SW; Toskala, E; van Cauwenberge, P; Vandenplas, O; van Weel, C; Viegi, G; Virchow, JC; Wang, DY; Wickman, M; Williams, D; Yawn, BP; Zar, HJ; Zernotti, M; Zhong, N
    P>The links between asthma and rhinitis are well characterized. The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines stress the importance of these links and provide guidance for their prevention and treatment. Despite effective treatments being available, too few patients receive appropriate medical care for both diseases. Most patients with rhinitis and asthma consult primary care physicians and therefore these physicians are encouraged to understand and use ARIA guidelines. Patients should also be informed about these guidelines to raise their awareness of optimal care and increase control of the two related diseases. To apply these guidelines, clinicians and patients need to understand how and why the recommendations were made. The goal of the ARIA guidelines is to provide recommendations about the best management options for most patients in most situations. These recommendations should be based on the best available evidence. Making recommendations requires the assessment of the quality of available evidence, deciding on the balance between benefits and downsides, consideration of patients' values and preferences, and, if applicable, resource implications. Guidelines must be updated as new management options become available or important new evidence emerges. Transparent reporting of guidelines facilitates understanding and acceptance, but implementation strategies need to be improved.
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    Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs
    Bousquet, J; Schünemann, HJ; Samolinski, B; Demoly, P; Baena-Cagnani, CE; Bachert, C; Bonini, S; Boulet, LP; Bousquet, PJ; Brozek, JL; Canonica, GW; Casale, TB; Cruz, AA; Fokkens, WJ; Fonseca, JA; van Wijk, RG; Grouse, L; Haahtela, T; Khaltaev, N; Kuna, P; Lockey, RF; Carlsen, KCL; Mullol, J; Naclerio, R; O'Hehir, RE; Ohta, K; Palkonen, S; Papadopoulos, NG; Passalacqua, G; Pawankar, R; Price, D; Ryan, D; Simons, FER; Togias, A; Williams, D; Yorgancioglu, A; Yusuf, OM; Aberer, W; Adachi, M; Agache, I; Aït-Khaled, N; Akdis, CA; Andrianarisoa, A; Annesi-Maesano, I; Ansotegui, IJ; Baiardini, I; Bateman, ED; Bedbrook, A; Beghé, B; Beji, M; Bel, EH; Ben Kheder, A; Bennoor, KS; Bergmann, KC; Berrissoul, F; Bieber, T; Jensen, CB; Blaiss, MS; Boner, AL; Bouchard, J; Braido, F; Brightling, CE; Bush, A; Caballero, F; Calderon, MA; Calvo, MA; Camargos, PAM; Caraballo, LR; Carlsen, KH; Carr, W; Cepeda, AM; Cesario, A; Chavannes, NH; Chen, YZ; Chiriac, AM; Pérez, TC; Chkhartishvili, E; Ciprandi, G; Costa, DJ; Cox, L; Custovic, A; Dahl, R; Darsow, U; De Blay, F; Deleanu, D; Denburg, JA; Devillier, P; Didi, T; Dokic, D; Dolen, WK; Douagui, H; Dubakiene, R; Durham, SR; Dykewicz, MS; El-Gamal, Y; El-Meziane, A; Emuzyte, R; Fiocchi, A; Fletcher, M; Fukuda, T; Gamkrelidze, A; Gereda, JE; Diaz, SG; Gotua, M; Guzmán, MA; Hellings, PW; Hellquist-Dahl, B; Horak, F; Hourihane, JO; Howarth, P; Humbert, M; Ivancevich, JC; Jackson, C; Just, J; Kalayci, O; Kaliner, MA; Kalyoncu, AF; Keil, T; Keith, PK; Khayat, G; Kim, YY; N'Goran, BK; Koppelman, GH; Kowalski, ML; Kull, I; Kvedariene, V; Larenas-Linnemann, D; Le, LT; Lemière, C; Li, J; Lieberman, P; Lipworth, B; Mahboub, B; Makela, MJ; Martin, F; Marshall, GD; Martinez, FD; Masjedi, MR; Maurer, M; Mavale-Manuel, S; Mazon, A; Melen, E; Meltzer, EO; Mendez, NH; Merk, H; Mihaltan, F; Mohammad, Y; Morais-Almeida, M; Muraro, A; Nafti, S; Namazova-Baranova, L; Nekam, K; Neou, A; Niggemann, B; Nizankowska-Mogilnicka, E; Nyembue, TD; Okamoto, Y; Okubo, K; Orru, MP; Ouedraogo, S; Ozdemir, C; Panzner, P; Pali-Schöll, I; Park, HS; Pigearias, B; Pohl, W; Popov, TA; Postma, DS; Potter, P; Rabe, KF; Ratomaharo, J; Reitamo, S; Ring, J; Roberts, R; Rogala, B; Romano, A; Rodriguez, MR; Rosado-Pinto, J; Rosenwasser, L; Rottem, M; Sanchez-Borges, M; Scadding, GK; Schmid-Grendelmeier, P; Sheikh, A; Sisul, JC; Solé, D; Sooronbaev, T; Spicak, V; Spranger, O; Stein, RT; Stoloff, SW; Sunyer, J; Szczeklik, A; Todo-Bom, A; Toskala, E; Tremblay, Y; Valenta, R; Valero, AL; Valeyre, D; Valiulis, A; Valovirta, E; Van Cauwenberge, P; Vandenplas, O; van Weel, C; Vichyanond, P; Viegi, G; Wang, DY; Wickman, M; Wöhrl, S; Wright, J; Yawn, BP; Yiallouros, PK; Zar, HJ; Zernotti, ME; Zhong, N; Zidarn, M; Zuberbier, T
    Allergic rhinitis (AR) and asthma represent global health problems for all age groups. Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact on Asthma (ARIA) was initiated during a World Health Organization workshop in 1999 (published in 2001). ARIA has reclassified ARas mild/moderate-severe and intermittent/persistent. This classification closely reflects patients' needs and underlines the close relationship between rhinitis and asthma. Patients, clinicians, and other health care professionals are confronted with various treatment choices for the management of AR. This contributes to considerable variation in clinical practice, and worldwide, patients, clinicians, and other health care professionals are faced with uncertainty about the relative merits and downsides of the various treatment options. In its 2010 Revision, ARIA developed clinical practice guidelines for the management of AR and asthma comorbidities based on the Grading of Recommendation, Assessment, Development and Evaluation (GRADE) system. ARIA is disseminated and implemented in more than 50 countries of the world. Ten years after the publication of the ARIAWorld Health Organization workshop report, it is important to make a summary of its achievements and identify the still unmet clinical, research, and implementation needs to strengthen the 2011 European Union Priority on allergy and asthma in children. (J Allergy Clin Immunol 2012;130:1049-62.)
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    ARIA (Allergic rhinitis and its impact on asthma) Achievements in 10 years and future needs
    Yorgancioglu, A; Özdemir, C; Kalayci, Ö; Kalyoncu, AF; Bachert, C; Baena-Cagnani, CE; Casale, TB; Chen, YZ; Cruz, AA; Demoly, P; Fokkens, WJ; Carlsen, KCL; Mohammad, Y; Mullol, J; Ohta, K; Papadopoulos, NG; Pawankar, R; Samolinski, B; Schüemann, HJ; Yusuf, OM; Zuberbier, T; Bousquet, J
    Allergic rhinitis and asthma represent global health problems for all age groups. Asthma and rhinitis frequently co-exist in the same subjects. Allergic Rhinitis and its Impact on Asthma (ARIA) was initiated during a World Health Organization (WHO) workshop in 1999 and was published in 2001. ARIA has reclassified allergic rhinitis as mild/moderate-severe and intermittent/persistent. This classification schema closely reflects the impact of allergic rhinitis on patients. In its 2010 Revision, ARIA developed clinical practice guidelines for the management of allergic rhinitis and asthma co-morbidities based on GRADE (Grading of Recommendation, Assessment, Development and Evaluation). ARIA has been disseminated and implemented in over 50 countries of the world. In Turkey, it is important to make a record of ARIA achievements and to identify the still unmet clinical, research and implementation needs in order to strengthen the 2011 EU Priority on allergy and asthma in children.
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    A strategy for measuring health outcomes and evaluating impacts of interventions on asthma and COPD-common chronic respiratory diseases in Global Alliance against Chronic Respiratory Diseases (GARD) countries
    To, T; Cruz, AA; Viegi, G; McGihon, R; Khaltaev, N; Yorgancioglu, A; Camargos, PA; La Grutta, S; Baena-Cagnani, CE; Haahtela, T; Billo, NE; Schraufngael, DE; Bousquet, J
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    What we should learn from the London Olympics
    Bonini, M; Bachert, C; Baena-Cagnani, CE; Bedbrook, A; Brozek, JL; Canonica, GW; Cruz, AA; Fokkens, WJ; van Wijk, RG; Grouse, L; Hellings, PW; Howarth, P; Kalayci, O; Khaltaev, N; Kuna, P; Linnemann, DL; Nekam, K; Palkonen, S; Papadopoulos, NG; Popov, TA; Price, D; Pinto, JR; Rasi, G; Ryan, D; Samolinski, B; Scadding, GK; Schünemann, HJ; Thomas, DM; Triggiani, M; Yorgancioglu, A; Yusuf, OM; Zuberbier, T; Pawankar, R; Bousquet, J; Bonini, S