Browsing by Author "Bagci, M"
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Item Impact effect on different sized reinforced concrete specimens(NATL INST SCIENCE COMMUNICATION-NISCAIR) Erdem, RT; Gucuyen, E; Kantar, E; Bagci, MBehavior of structural members under various loads has been a major interest. However, impact loading type is the least known one among them. Researchers have investigated the behavior of structural members under impact effect recently. For this reason, a well-instrumented experimental program is used to understand the impact behavior of six different sized reinforced concrete specimens. All specimens both have longitudinal and transverse reinforcements. A testing apparatus is developed to perform tests under impact loading. Accelerometers, optic photocells, dynamic force sensor, a data logger and connecting cables are used as well as testing apparatus. Free falling height and mass of steel hammer are taken constant in the study. Test program has been successful to provide several data to understand the impact behavior. Drop numbers and rebound movements of the hammer are determined according to damage situations. Acceleration values are measured from four different points of the specimens. The change of velocity and displacement values is determined for all specimens. Impact force is also measured for each free falling movement and absorbed energy values are calculated according to the area under the curve of impact force-displacement graphs. Test results give substantial information about impact resistances of reinforced concrete members.Item RC beam strengthening using precast RC plate bonding technique(CROATIAN SOC CIVIL ENGINEERS-HSGI) Demir, A; Bagci, M; Tekin, M; Nuhoglu, AThe behaviour of RC beams strengthened with precast RC plates of rectangular and U cross-section is studied in the paper. An experimental investigation was conducted to assess effectiveness of strengthening with precast plates. The investigation was supported with the 2-D nonlinear finite element analysis (NLFEA). The NLFEA results showed a good level of correlation with test results. The proposed technique is considered to be a good alternative to RC jacketing and the technique is practical, economical and reliable for buildings or bridges with a greater number sisof similar beams.Item Experimental and numerical investigation of walls strengthened with fiber plaster(TECHNO-PRESS) Basaran, H; Demir, A; Bagci, M; Ergun, SThe topic of this study is to investigate behaviors of masonry walls strengthened with reinforced fiber plaster under diagonal tensile loads. Full blend brick 100x50x30 mm in dimensions were used to make masonry walls with dimensions of 400x400x100 mm. Three different samples were manufactured by plastering masonry walls with traditional style, with 3% polypropylene or with 5% steel fiber. All the samples were tested using ASTM 1391- 81 standards. The propagation of damage on samples caused by diagonal tensile load was observed and load-displacement graphs were plotted for each sample. A finite element software (ABAQUS) was used to obtain numerical values for all samples and crack patterns and load-displacement responses were obtained. Experimental and numerical results were compared.Item Shaking table study of masonry buildings with reinforced plaster(CROATIAN SOC CIVIL ENGINEERS-HSGI) Basaran, H; Demir, A; Bagci, M; Ercan, EThe objective of this study is to determine seismic behaviour of masonry buildings with reinforced plaster mortar, with a particular focus on the modification of structural response due to application of the polypropylene and steel reinforced plaster, as compared to an ordinary type of plaster. The resistance of one-storey single-span masonry buildings subjected to seismic load on the shaking table is investigated in the study. Experimental results revealed natural periods, response acceleration spectrums, and spectrum interactions of masonry buildings. In addition, finite element models of test buildings were established, and their results were compared with those obtained during experimental study.Item NEURAL NETWORK MODEL FOR MOMENT-CURVATURE RELATIONSHIP OF REINFORCED CONCRETE SECTIONS(ASSOC SCI RES) Bagci, MThe analysis of moment-curvature relationship of reinforced concrete sections is complex due to large number of variables as well as non-linear material behavior involved. Artificial Neural Networks (ANNs) are found to be a tool capable of solving such problems. This has led to increasing use of ANN for analyzing the behavior of reinforced concrete sections. This paper reports the details of a study conducted using ANN for predicting moment-curvature relationship of a reinforced concrete section. Using data generated based on the analytical solutions, the ANN model was trained. The trained model was tested for a different set of input parameters and the output values were compared with the values based on analytical results. The agreement was found to be good.Item The Behavior of Masonry Walls with Reinforced Plaster Mortar(HINDAWI LTD) Basaran, H; Demir, A; Bagci, MThe purpose of this study is the improvement of the behaviors of walls constructed with masonry bricks using reinforced plaster mortars. In this study, 400 x 400 x 100 mm sized walls were constructed using 1 : 2 scaled 100 x 50 x 30 mm sized masonry bricks. The walls were plastered using normal and various proportions of polypropylene and steel fiber reinforced plaster mortars and were subjected to vertical loads at 30 degrees, 45 degrees, 60 degrees, and 90 degrees angles. As a result of the experiments, attempts were made to present the strength, stiffness, and ductility of all of the walls. At the end of the study, an evaluation concerning failure envelope curve (sigma-tau) obtained from test results according to plastered masonry walls types was performed.Item A Real-Life Turkish Experience of Ruxolitinib in Polycythemia Vera(GALENOS PUBL HOUSE) Serin, I; Dogu, MH; Ekinci, O; Cagliyan, GA; Bastürk, A; Aras, MR; Demircioglu, S; Turgut, B; Merter, M; Hacioglu, SK; Bagci, M; Albayrak, M; Korkmaz, S; Erkurt, MA; Dal, MS; Dursun, FE; Tombak, A; Aydogdu, I; Ulas, T; Altuntas, FIntroduction: Ruxolitinib is a small -molecule inhibitor of the JAK1/2 pathway. This study aimed to reveal the results and side-effect profile of the use of ruxolitinib as a treatment option in polycythemia vera (PV). Methods: A total of 34 patients with PV from 18 different centers were included in the study. The evaluation of the response under treatment with ruxolitinib was determined as a reduction in spleen volume (splenomegaly size: >= 35%) by imaging and control of hematocrit levels (<= 45%) compared to baseline. Results: While the number of patients in which a reduction in spleen volume and hematocrit control was achieved was 19 (55.9%) at 3 months of treatment, it was 21 (61.8%) at 6 months. Additionally, while the number of side effects was negatively correlated with the reduction in spleen volume (Spearman's rho: -0.365, p=0.034), a decrease in the hematocrit level was positively correlated (Spearman's rho: 0.75, p=0.029). Those without a reduction in spleen volume experienced more constipation (chi-square: 5.988, Fisher's exact test: p=0.033). Conclusion: This study shed light on the use of ruxolitinib in PV and the importance of splenomegaly on studies planned with larger patient groups.Item Artificial neural network analysis of infilled planar frames(THOMAS TELFORD PUBLISHING) Bagci, M; Altintas, GIn this study, infilled planar frames have been analysed using an artificial neural network. The data used were provided by a finite element model (FEM) in which non-linearity of materials and the structural interface were taken into account under increasing lateral load. For the skeleton frame, the panel was modelled by a two-noded frame element and a four-noded isoparametric element respectively. The Von Mises failure criterion was used for the infill wall. Values obtained from FEM were used in training the network established. An artificial neural network (ANN) architecture was chosen in which a multilayer, feed-forward and back-propagation algorithm was used. The controls conducted in the test phase showed that training was satisfactory. The study has proved that the ANN could be successfully used for analysis of infilled planar frames.Item The clinicopathological features and survival of Castleman disease: a multicenter Turkish study(VERDUCI PUBLISHER) Yildiz, J; Bagci, M; Sayin, S; Kaya, A; Yilmaz, F; Ekinci, O; Dal, MS; Basturk, A; Aydogdu, I; Albayrak, M; Dogan, A; Erkurt, MA; Korkmaz, S; Ulas, T; Eser, B; Altuntas, FOBJECTIVE: In this study, we aimed to investigate the clinicopathological features and survival of CD, which is quite rare and has many unknowns. PATIENTS AND METHODS: This study was conducted by retrospectively evaluating patients diagnosed with CD in six different centers in Turkey. RESULTS: The median age of 33 patients included in the study was 49 and 51.5% (n = 17) of these patients were women. 18 (54.5%) patients were in the hyaline vascular subtype and most of the patients were UCD (n = 20, 60.6%). The most common involvement region was head and neck (n = 19, 57.5%). The UCD group was younger than the MCD group (p=0.027). Visceral lymph node involvement was higher in MCD than in UCD (p=0.001). Similarly, it was observed that there was more hepatomegaly (p=0.035) and splenomegaly (p=0.013) in the MCD group. During the median 19.5 months follow-up period, there were no patients who died. CONCLUSIONS: It was observed that UCD and MCD are different clinical entities. Promising survival times can be achieved with surgical and systemic treatments in both subtypes of this extremely rare disease. However, this re- suit should be supported by well-designed prospective comprehensive studies.Item Strengthening of RC beams with prefabricated RC U cross-sectional plates(TECHNO-PRESS) Demir, A; Tekin, M; Turali, T; Bagci, MThe topic of this study is to strengthen cracked beams with prefabricated RC U cross-sectional plates. The damaged beams were repaired by epoxy based glue. The repaired beams were strengthened using prefabricated plates. The strengthening plates were bonded to the bottom and side faces of the beams by anchorage rods and epoxy. The strengthened beams were incrementally loaded up to maximum load capacities. The experimental results were satisfactory since the load carrying capacities of damaged beams were increased approximately 76% due to strengthening. It was observed that strengthening plates had a dominant effect on the performance of beams in terms of both the post-elastic strength enhancement and the ductility. The experimental program was supported by a three-dimensional nonlinear finite element analysis. The experimental results were compared with the results obtained from the beam modeled with ANSYS finite element program.Item EFFECTS OF FIBER REINFORCED PLASTER ON THE EARTHQUAKE BEHAVIOR OF MASONRY BUILDINGS(SPRINGER INTERNATIONAL PUBLISHING AG) Basaran, H; Demir, A; Bagci, M; Ercan, EIn this paper the traditional covering plaster of masonry buildings is supplied with Polypropylene and steel fiber to enhance their seismic behavior. The plaster mix proportion is determined by some initial mortar tests. Also, one story, single span masonry building specimen plastered with different mortars is tested on a shaking table 8 times under a seismic input and the performance of the specimens with the above types of mortar is evaluated. The specimen plastered with a traditional plaster was regarded as control and its earthquake behavior was compared to that reinforced by fiber plaster. Steel fiber or polypropylene addition significantly increased stiffness, displacement ability and energy consumption ability of specimens as compared to control. The suggested reinforcement method was proven to strengthen masonry buildings in a fast, reliable and economical way. Moreover, it can easily be adapted to any masonry building without causing any negative impact. The suggested method is fire and corrosion resistant.Item Impact behaviour of concrete beams(CROATIAN SOC CIVIL ENGINEERS-HSGI) Erdem, RT; Gucuyen, E; Kantar, E; Bagci, MThe determination of behaviour of structural members under load has become increasingly prominent with current advances in technology. The effect of impact on solids should not be ignored. The impact behaviour of non-reinforced concrete beams is investigated in this study both experimentally and using the finite element analysis. Members are tested in laboratory, and the ABAQUS software is used in the analysis. Accelerations, velocities, displacements, impact forces, and energy absorption capacities, have been obtained in the scope of these analyses.Item The Real-World Experience With Single Agent Ibrutinib in Relapsed/Refractory CLL(CIG MEDIA GROUP, LP) Akpinar, S; Dogu, MH; Celik, S; Ekinci, O; Hindilerden, IY; Dal, MS; Davulcu, EA; Tekinalp, A; Hindilerden, F; Ozcan, BG; Hacibekiroglu, T; Erkurt, MA; Bagci, M; Namdaroglu, S; Korkmaz, G; Bilgir, O; Cagliyan, GA; Ozturk, HBA; Serin, I; Tiryaki, TO; Ozatli, D; Korkmaz, S; Ulas, T; Eser, B; Turgut, B; Altuntas, FWe evaluated the safety and efficacy of single-agent ibrutinib in 200 patients presenting with relapsed/refractory CLL in real-world settings. With an estimated median OS of 52 months, 146 patients (75%) achieved at least PR; 16 (8.7%) patients discontinued ibrutinib due to adverse events. The results indicate good safety and efficacy for single-agent ibrutinib in R/R CLL in daily practice. Introduction/Background: The emergence of novel agents targeting the B-cell receptor pathway and BCL-2 has significantly changed the therapeutic landscape of CLL. We evaluated the safety and efficacy of single-agent ibrutinib in relapsed/refractory CLL in real-world settings. Patients/Methods: A total of 200 relapsed/refractory CLL patients with a median age of 68 were included in this retrospective, multicenter, non-interventional study. Data of the study were captured from the patient charts of the par ticipating centers. Results: The median for lines of previous chemotherapy was 2 (1-6); 62 (31.8%) patients had del17p and/or p53 mutations (del17p+ /p53mut). Of the study group, 146 (75%) patients achieved at least PR, while 16 (8.7%) patients discontinued ibrutinib due to TEA. The most common drug-related adverse events were neutropenia (n: 31; 17.4%) and thrombocytopenia (n: 40; 22.3%), which were >= grade 3 in 9 (5%) and 5 (3.9%) patients, respectively. Pneumonia (n: 42; 23.7%) was the most common nonhematologic TEA. Atr ial fibrillation (n: 5; 2.8%) and bleeding (n: 11; 6.3%) were relatively rare dur ing the study period. Within a median follow-up period of 17 (1-74) months, 42 (21%) patients died. The estimated median OS of the study cohort was 52 months. Only the response to ibrutinib (CR/PR vs. SD/PD) was significantly associated with OS. Conclusion: Our results indicate good safety and efficacy for single-agent ibrutinib in R/R CLL in daily practice. (C) 2021 Elsevier Inc. All rights reserved.Item Determination of the steady-state response of viscoelastically supported rectangular orthotropic mass loaded plates by an energy-based finite difference method(SAGE PUBLICATIONS LTD) Altintas, G; Bagci, MA method based on a variational procedure in conjunction with a finite difference method is used to examine the free vibration characteristics and steady-state response to a sinusoidally varying force applied orthotropic elastic rectangular plate carrying masses, Using the energy-based finite difference method, the problem reduced to the solution of a system of algebraic equations. Due to the significance of the fundamental natural frequency of the plate, its variation is investigated with respect to the mechanical properties of the plate material, the translational spring coefficient of the supports, the mass distribution, the mass locations and the quantity of mass. The steady-state response of the viscoelastically supported plates was also investigated numerically for the damping coefficient of the supports and the force distribution in addition to the characteristics of the plate system. Many new results are presented and the validity of the present approach is demonstrated by comparing the results with other solutions based on the Kirchhoff-Love plate theory.